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Bernstein, Paul S.; Gellermann, Werner | Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions. | We have developed a CCD-camera-based nonmydriatic instrument that detects fluorescence from retinal lipofuscin chromophores ("autofluorescence") as a means to indirectly quantify and spatially image the distribution of macular pigment (MP). The lipofuscin fluorescence intensity is reduced at all ret... | Cytology; Sensitivity and Specificity | 2006-10 |
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Bernstein, Paul S.; Gellermann, Werner | Macular pigment Raman detector for clinical applications | Clinical studies of carotenoid macular pigments (MP) have been limited by the lack of noninvasive, objective instruments. We introduce a novel noninvasive optical instrument, an MP Raman detector, for assessment of the carotenoid status of the human retina in vivo. The instrument uses resonant excit... | Diagnosis, Computer-Assisted; Equipment Failure Analysis; Sensitivity and Specificity | 2004 |