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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Gesteland, Raymond F.; Atkins, John F.; Baranov, Pavel V. | P-site tRNA is a crucial initiator of ribosomal frameshifting | The expression of some genes requires a high proportion of ribosomes to shift at a specific site into one of the two alternative frames. This utilized frameshifting provides a unique tool for studying reading frame control. Peptidyl-tRNA slippage has been invoked to explain many cases of programmed ... | Translation; Recoding; Kinetic Model; Frameshifting; Ribosome | 2004 |
| 2 |
 | Gesteland, Raymond F.; Ivanov, Ivaylo P.; Atkins, John F. | Programmed frameshifting in the synthesis of mammalian antizyme is +1 in mammals, predominantly +1 in fission yeast but "2 in budding yeast | The coding sequence for mammalian ornithine decarboxylase antizyme is in two different partially overlapping reading frames with no independent ribosome entry to the second ORF. Immediately before the stop codon of the first ORF, a proportion of ribosomes undergo a quadruplet translocation event t... | Antizyme; Frameshifting; Ornithine decarboxylase antizyme; Recoding; S. pombe | 1998 |
| 3 |
 | Gesteland, Raymond F.; Atkins, John F.; Howard, Michael T. | Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides | Evidence is presented that morpholino, 2_x0001_-O-methyl, phosphorothioate, and RNA antisense oligonucleotides can direct sitespecific âˆ'1 translational frameshifting when annealed to mRNA downstream from sequences where the P- and A-site tRNAs are both capable of re-pairing with âˆ'1 frame c... | Recoding; Frameshifting; Antisense; Morpholino; Phosphorothioate; 2_x0001_-O-methyl | 2004 |
| 4 |
 | Gesteland, Raymond F.; Atkins, John F. | Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression | Translating ribosomes can shift reading frame at specific sites with high efficiency for gene expression purposes. The most common type of shift to the 1 frame involves a tandem realignment of two anticodons from pairing with mRNA sequence of the form X XXY YYZ to XXX YYY Z where the spaces indicate... | 1 frameshifting; 39 context effect; Codon anticodon interaction; Escherichia coli ; Recoding; tRNALys; XXXY YYZ frameshift motifs | 2002 |
| 5 |
 | Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M. | Upstream stimulators for recoding | Recent progress in elucidation of 5' stimulatory elements for translational recoding is reviewed. A 5' Shine-Dalgarno sequence increases both +l and ? I frameshift efficiency in several genes; examples cited include the E. coli prfB gene encoding release factor 2 and the thuiX gene encoding the y an... | Recoding; Frameshifting; Peptide factor; Stimulatory elements | 1995 |
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