Filters: Collection: "ir_uspace" Subject: "Kidney"
1 - 25 of 2
| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
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Capecchi, Mario R. | Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. | We have used site-specific mutagenesis to change the anticodon of a Xenopus laevis tyrosine tRNA gene so that it would recognize ochre codons. This tRNA gene is expressed when amplified in monkey cells as part of a SV40 recombinant and efficiently suppresses termination at both the ochre codon separ... | Xenopus; Nucleic Acid Conformation; Kidney; DNA Restriction Enzymes | 1984-11 |
| 2 |
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Capecchi, Mario R. | Lessons from angiotensin-converting enzyme-deficient mice. | Mice which lack ACE have low systolic blood pressure, reduced male fertility and a renal abnormality characterized by medullary hypoplasia and the inability to concentrate urine. The diverse phenotypes caused by inactivation of a single gene emphasize the many functional roles of ACE and the renin-q... | Blood Pressure; Cell Line;Fertility; Kidney; Testis | 1991-11-01 |
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