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CreatorTitleDescriptionSubjectDate
1 Christensen, Douglas A.; Herron, James N.Rapid clinical diagnostics assays using injection-molded planar waveguidesThe goal of our research program is to develop an evanescent wave immunoassay system that can be used in point-of-care and critical care settings. Several key attributes are required to accomplish this goal: (i) the assay system should be at least as sensitive as present day immunoassays; (ii) assay...Planar waveguides; Creatine phosphokinase MB (CK-MB); Cardiac troponin I (cTnl); Diagnostics; Evanescence; Fluorescence; Human chorionic gonadotropin (hCG)1998
2 Sokolsky, PierreFirst observation of the Greisen-Zatsepin-Kuzmin suppressionThe High Resolution Fly's Eye (HiRes) experiment has observed the Greisen-Zatsepin-Kuzmin suppression (called the GZK cutoff) with a statistical significance of five standard deviations. HiRes' measurement of the flux of ultrahigh energy cosmic rays shows a sharp suppression at an energy of 6 x 10^1...Extensive air showers; Suppression; Energy spectrum; Fluorescence; GZK cutoff2008-03
3 Sokolsky, PierreEnergy estimation of UHE cosmic rays using the atmospheric fluorescence techniqueWe use the CORSIKA air shower simulation program to review the method for assigning energies to ultra-high energy (UHE) cosmic rays viewed with the air fluorescence technique. This technique uses the atmosphere as a calorimeter, and we determine the corrections that must be made to the calorimetric ...Fluorescence; Energy estimation; Ultra-high energy cosmic rays2000-08
4 Sokolsky, PierreMeasurement of the flux of ultrahigh energy cosmic rays from monocular observations by the High Resolution Fly's Eye experimentWe have measured the cosmic ray spectrum above 1017.2 eV using the two air-fluorescence detectors of the High Resolution Fly's Eye observatory operating in monocular mode.We describe the detector, phototube, and atmospheric calibrations, as well as the analysis techniques for the two detectors.We fi...Extensive air showers; Fluorescence; Energy spectrum2004-04
5 Sokolsky, PierreMeasurement of the flux of ultra high energy cosmic rays by the stereo techniqueThe High Resolution Fly's Eye (HiRes) experiment has measured the flux of ultrahigh energy cosmic rays using the stereoscopic air fluorescence technique. The HiRes experiment consists of two detectors that observe cosmic ray showers via the fluorescence light they emit. HiRes data can be analyzed i...Ultrahigh energy cosmic rays; Fluorescence; Energy spectrum; GZK cutoff2009-08
6 Christensen, Douglas A.; Herron, James N.Rapid single nucleotide polymorphism detection for personalized medicine applications using planar waveguide fluorescence sensorsPersonalized medicine is an emerging field in which clinical diagnostics information about a patient's genotype or phenotype is used to optimize his/her pharmacotherapy. This article evaluates whether planar waveguide fluorescent sensors are suitable for determining such information from patient tes...Personalized medicine; Planar waveguides; Fluorescence sensors; Evanescent excitation; Fluorescence; Hybridization; Molecular diagnostics; Peptide nucleic acid; Point of care; Single base extension; Single nucleotide polymorphism2006
7 Sokolsky, PierreEffect of clouds on apertures of space-based air fluorescence detectorsSpace-based ultra-high-energy cosmic ray detectors observe fluorescence light from extensive air showers produced by these particles in the troposphere. Clouds can scatter and absorb this light and produce systematic errors in energy determination and spectrum normalization. We study the possibilit...Fluorescence; Cloud detection; Extensive air showers2004-01
8 Sokolsky, PierreHighest energy cosmic rays and results from the HiRes experimentThe status of the field of ultrahigh energy cosmic ray physics is summarized, from the point of view of the latest results of the High Resolution Fly's Eye (HiRes) Experiment. HiRes results are presented, and compared with those of the Akeno Giant Air Shower Array (AGASA), plus the Telescope Array ...Fluorescence; Energy spectrum; GZK cutoff; Extensive air showers; Anisotropy2007-11-01
9 Sokolsky, PierreEvidence for changing of cosmic ray composition between 10^17 and 10^18 eV from multicomponent measurementsThe average mass composition of cosmic rays with primary energies between 1017 and 1018 eV has been studied using a hybrid detector consisting of the High Resolution Fly's Eye (HiRes) prototype and the MIA muon array. Measurements have been made of the change in the depth of shower maximum and the...Extensive air showers; Fluorescence; Energy spectrum; Muon density; Cherenkov light2000-05
10 Christensen, Douglas A.; Herron, James N.Comparison of robust coupling techniques for planar waveguide immunosensorsWe have analyzed and fabricated two different coupling schemes to meet the requirements for a convenient means of coupling into a planar waveguide immunosensor that is relatively insensitive to beam alignment. These are the "launch" coupler and the grating coupler. Each possesses advantages and dis...Planar waveguide immunosensors; Fluorescence; Launch coupler; Grating coupler1993
11 Sokolsky, PierreUltra high energy ντ detection with a cosmic ray tau neutrino telescope used in fluorescence/Cerenkov light detectionWe have investigated the possibility of ντ detection using Cosmic Ray Tau Neutrino Telescope (CRTNT) based on air shower fluorescence/Cerenkov light detector techniques. This approach requires an interaction of a νг with material such as a mountain or the earth's crust. lepton produced in th...Tau neutrino; Tau lepton; Fluorescence; Cerenkov light2005-07-01
12 Christensen, Douglas A.Planar waveguide biosensors for nucleic acid hybridization reactionsOligonucleotide probes derived from (1) the T3 RNA polymerase promoter sequence (T3) and (2) prostate-specific antigen messenger RNA (PSA) were prepared and labeled with a red-emitting fluorescent dye (Cy5). The complimentary oligonucleotides (anti T3 and anti PSA) were prepared and labeled with bio...Planar waveguides; Evanescence; Fluorescence; Glandular kallikrein; MDx; Molecular diagnostics; Nucleic acid; PSA; Oligonucleotide probes2000
13 Sokolsky, PierreObserving the ultrahigh energy universe with OWL eyesThe goal of the Orbiting Wide-field Light-collectors (OWL) mission is to study the origin and physics of the highest energy particles known in nature, the ultrahigh energy cosmic rays (UHECRs). The OWL mission consists of telescopes with UV sensitive cameras on two satellites operating in tandem to ...Ultra-high energy cosmic rays; Fluorescence; Air showers2004-11
14 Sokolsky, PierreHigh Resolution Fly's Eye - status and preliminary results on cosmic ray composition above 10^18 eVWe describe the current status of the High Resolution Fly's Eye detector. Event reconstruction and associated systematics for stereo reconstruction are discussed and recent preliminary results on the study of the composition of ultra-high energy cosmic rays by the Xmax method are presented. These r...Ultra-high energy cosmic rays; Fluorescence; Stereo detection2002
15 Sokolsky, PierreObservation of the suppression of the flux of cosmic rays above 4×10^19eVThe energy spectrum of cosmic rays above 2.5 x 10^18 eV, derived from 20 000 events recorded at the Pierre Auger Observatory, is described. The spectral index γ of the particle flux, J∞ E-γ, at energies between 4 x 10^18 eV and 4 x 10^19 eV is 2.69 ± 0.02(stat) ± 0.06(syst), steepening to 4.2 ...Extensive air showers; Energy spectrum; Fluorescence; Suppression2008-08
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