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| Creator | Title | Description | Subject | Date | ||
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Zick, Cathleen D.; Srisukhumbowornchai, Sivithee | Does housework matter anymore? The shifting impact of housework on economic inequality | In recent years, American women's housework time has declined while American men's housework time has risen. We examine how these changes have affected economic inequality in America. Using time-diary data from the Time Use in Economic and Social Accounts, 1975-76 (N=1,484) and the American Time Use... | Demography; Socioeconomic status; Household duties; Female; Male; United States; Economics | 2006-09-25 |
| 2 |
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Capecchi, Mario R. | Illegitimate cre-dependent chromosome rearrangements in transgenic mouse spermatids. | The bacteriophage P1 Cre/loxP system has become a powerful tool for in vivo manipulation of the genomes of transgenic mice. Although in vitro studies have shown that Cre can catalyze recombination between cryptic "pseudo-loxP" sites in mammalian genomes, to date there have been no reports of loxP-si... | Chromatin; Female; Mice, Inbred C57BL; Phenotype | 2000-12-05 |
| 3 |
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Capecchi, Mario R. | Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system | Mammalian TBP consists of a 180 amino acid core that is common to all eukaryotes, fused to a vertebrate-specific N-terminal domain. We generated mice having a modified tbp allele, tbp(DeltaN), that produces a version of TBP lacking 111 of the 135 vertebrate-specific amino acids. Most tbp(DeltaN/Delt... | Alleles; Animals, Genetically Modified; Binding Sites; Embryonic and Fetal Development; Evolution, Molecular; Female; Fetus; Immune Tolerance; Male; Mice; Mutation; ATA-Box Binding Protein | 2002-07-12 |
| 4 |
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Thomas, Kirk R.; Capecchi, Mario R. | Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. | The int-1 proto-oncogene was first identified as a gene activated in virally induced mouse mammary tumours. Expression studies, however, suggest that the normal function of this gene may be in spermatogenesis and in the development of the central nervous system. Genes sharing sequence similarity wit... | Animals; Blastocyst; Cell Line; Chimera; DNA; Female; Genotype; Heterozygote; Homozygote; Male; Mice, Inbred C57BL; Motor Activity | 1990-08-30 |
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