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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Beckerle, Mary C. | Targeting of zyxin to sites of actin membrane interaction and to the nucleus | The localization of proteins to particular intracellular compartments often regulates their functions. Zyxin is a LIM protein found prominently at sites of cell adhesion, faintly in leading lamellipodia, and transiently in cell nuclei. Here we have performed a domain analysis to identify regions in ... | Zyxin; Actin; LIM domains; Focal adhesions; Lamellipodia; Cytoskeletal architecture | 2001 |
| 2 |
 | Beckerle, Mary C. | Cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation | In this report, an antisense RNA strategy has allowed us to show that disruption of ALP expression affects the expression of the muscle transcription factors myogenin and MyoD, resulting in the inhibition of muscle differentiation. Introduction of a MyoD expression construct into ALP-antisense cells... | Skeletal muscle; PDZ-LIM protein; Actin; Actinin-associated LIM proteins; Serum response factor; Cytoskeletal architecture | 2007 |
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