Creator | Title | Description | Subject | Date | ||
---|---|---|---|---|---|---|
1 |
![]() | Olivera, Baldomero M. | Single amino acid substitutions in ĸ-conotoxin PVIIA disrupt interaction with the Shaker K+ channel | ĸ-Conotoxin PVIIA (ĸ-PVIIA), a 27-amino acid peptide with three disulfide cross-links, isolated from the venom of Conus purpurascens, is the first conopeptide shown to inhibit the Shaker K1 channel (Terlau, H., Shon, K., Grilley, M., Stocker, M., Stühmer, W., and Olivera, B. M. (1996) Nature ... | Conotoxins; k-conotoxin PVIIA; Shaker K+ channels; Conus purpurascens | 2000 |
2 |
![]() | Olivera, Baldomero M.; Hillyard, David R.; Gray, William Robert | ĸ-Conotoxin PVIIA is a peptide inhibiting the Shaker K+ channel | ĸ-Conotoxin PVIIA (k-PVIIA), a 27-amino acid toxin from Conus purpurascens venom that inhibits the Shaker potassium channel, was chemically synthesized in a biologically active form. The disulfide connectivity of the peptide was determined. ĸ-Conotoxin PVIIA has the following structure. | Conotoxins; k-Conotoxin PVIIA; Conus purpurascens | 1998 |
3 |
![]() | Olivera, Baldomero M.; Gray, William Robert | New family of Conus peptides targeted to the nicotinic acetylcholine receptor | In this work, a new family of Conus peptides, the αA-conotoxins, which target the nicotinic acetylcholine receptor, is defined. The first members of this family have been characterized from the eastern Pacific species, Conus purpurascens (the purple cone); three peptides that cause paralysis in fis... | Conotoxins; Conus peptides; Conus purpurascens; Purple cone snail | 1995 |