Creator | Title | Description | Subject | Date | ||
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1 |
![]() | Olivera, Baldomero M.; McIntosh, J. Michael | Solution structure of αA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus | We report the solution three-dimensional structure of an αA-conotoxin EIVA determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. The αA-conotoxin EIVA consists of 30 amino acids representing the largest peptide among the α/αAfamily conotoxins discovered so f... | Conotoxins; A-conotoxin EIVA; Conus ermineus | 2003 |
2 |
![]() | Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael | Differential targeting of nicotinic acetylcholine receptors by novel αA-conotoxins | We describe the isolation and characterization of two peptide toxins from Conus ermineus venom targeted to nicotinic acetylcholine receptors (nAChRs). The peptide structures have been confirmed by mass spectrometry and chemical synthesis. In contrast to the 12-18 residue, 4 Cys-containing α-co... | Conotoxins; aA-conotoxins; Conus ermineus; Peptide toxins | 1997 |