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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
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Beckerle, Mary C. | ALP-enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans | Mutations that affect the Z-disk-associated ALP-Enigma proteins have been linked to human muscular and cardiac diseases. Despite their clear physiological significance for human health, the mechanism of action of ALP-Enigma proteins is largely unknown. In Caenorhabditis elegans, the ALP-Enigma prot... | Actin; Caenorhabditis elegans; Contractility; alp-1 mutants; Z-disks; Kettin | 2009 |
| 2 |
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Beckerle, Mary C.; Clark, Kathleen A. | Conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans | We describe here the molecular and functional characterization of the Caenorhabditis elegans unc-97 gene, whose gene product constitutes a novel component of muscular adherens junctions. UNC-97 and homologues from several other species define the PINCH family, a family of LIM proteins whose modula... | LIM domains; Caenorhabditis elegans; UNC-97; Adherens junction; Touch neuron; Muscle development | 1999 |
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