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| Creator | Title | Description | Subject | Date | ||
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. III. Biosynthesis from alternative precursors in vivo | In Escherichia coli, the nicotinamide moiety of pyridine nucleotides may be derived from de novo synthesis of the pyridine ring or through the uptake of either nicotinic acid or nicotinamide. De novo synthesis is the least preferred pathway; it is suppressed if an exogenous source is available. Nic... | Nicotinic acid; Biosynthesis | 1973 |
| 2 |
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Gouw, Launce G.; McKenna, Catherine K.; Digre, Kathleen B.; Placek, Louis J. | Analysis of the dynamic mutation in the SCA7 gene shows marked parental effects on CAG repeat transmission. | The gene for spinocerebellar ataxia 7 (SCA7) includes a transcribed, translated CAG tract that is expanded in SCA7 patients. We have determined expansions in 73 individuals from 17 SCA7 kindreds and compared them with repeat lengths of 180 unaffected individuals. Subjects with abnormal expansions co... | Genetics; Biosynthesis; SCA7 Gene | 1998-03-07 |
| 3 |
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Blumenthal, Donald K. | Identification of molecular sites on factor VII which mediate its assembly and function in the extrinsic pathway activation complex. | Factor VII-VIIa, in association with tissue factor, participates in the complex which initiates blood coagulation through the extrinsic pathway. To identify functional domains on factor VII which mediate the activation of factor X, 16 synthetic peptides corresponding to 55% of the primary structure ... | Genetics; Biosynthesis; Pharmacology | 1991-01-15 |
| 4 |
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Poulter, Charles Dale | Isolation of Schizosaccharomyces pombe isopentenyl diphosphate isomerase cDNA clones by complementation and synthesis of the enzyme in Escherichia coli | Isopentenyl diphosphate (IPP) isomerase catalyzes an essential activation step in the isoprene biosynthetic pathway. The Saccharomyces cerevisiae gene for IPP isomerase, IDI1, was recently isolated and characterized (Anderson, M. S., Muehlbacher, M., Street, I. P., Proffitt, J., and Poulter, C. D. (... | Carbon-Carbon; Biosynthesis; Genetics | 1995-05-12 |
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