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1 Lusted, KitselTemperature dependence of leptospirillum ferriphilum during biooxidation of pyriteRare earth elements have properties that make them useful in advanced electronics, magnets, and batteries. However, they are difficult to isolate from their constituent elements, which results in an environmentally costly operation to refine them. An environmentally friendly alternative extraction m...2023
2 Munn, JacksonDetermining microbial community composition and methane flux or red butte canyon sediment over timeMethane is a potent greenhouse gas that is released from the soil into the atmosphere, which contributes heavily to global warming. One potential way of reducing the amount of methane in the air is through studying methane consuming bacteria (methanotrophs) and how they interact with other microbes ...2022
3 Koblanski, KasperLiver foxn3 increases pancreatic a-cell mass without altering hepatic amino acid utilizationInsulin injection into peripheral tissues inefficiently controls elevated fasting blood glucose in type 1 diabetes mellitus (DM1) patients. Peripheral insulin lacks the signaling of healthy β-cell insulin, which directs adjacent pancreatic α-cells to stop production of glucagon, a hormone releasin...2022
4 Tazehabadi, TaraBioinformatics to detect functional interactions important for the DNA repair enzyme mutyhDNA is the blueprint of all biological life as it provides the means necessary for sharing of genetic information. DNA is formed and stabilized by interactions between four unique bases, Adenine (A), Cytosine (C), Guanine (G), and Thymine (T) which come together in predetermined patterns to create a...2022
5 Chatard, KendalOrangutan genetic load and the effects of population sizeGenetic load is a relative measure of the quantity of harmful mutations within a genome, and a population's demographic history can affect this measure. Small populations that have undergone a severe bottleneck have increased inbreeding. These factors can decrease genetic diversity and fix deleterio...2022
6 Scott, BrooklynGenomic insights into lineage specific differences in macaque social behaviorStudies of behavioral variation in primates are increasingly examining the role that genes have in determining social styles. The genus Macaca, for which phylogeny plays a central role in behavior, represents a useful group to explore behavioral genetics. Differences in macaque aggression and age of...2021
7 Enriquez, Trisha Pauline DiazSubstrate use within the drosophila melanogaster species subgroupEffective sensory perception is a vital aspect of survival for living organisms such as Drosophila. More specifically, olfaction, or the sense of smell, is essential because the detection of odors allows it to find potential food, danger, or specifically, where to lay eggs. This review will examine ...2021
8 Gates, AbigailHealth Care in the United States: Disparities and Distrust in the Black CommunityDuring the time of slavery, Black and African Americans were mistreated and abused as research subjects in medical studies. This mistreatment continued into the 20th century with the Tuskegee Syphilis study and continues today in many doctor's offices throughout America. This paper begins by looking...2020
9 Wang, Karissa M.Transcription factor NFATc1's signaling pathway and role in cardiomyocyte functionAtrial fibrillation (AF) is the most common sustained arrhythmia. It affects as many as 6.1 million people in the United States and increases their risk of stroke by 4-5 times. AF is evidently a very serious condition, but the scientific community does not yet fully understand its underlying mechani...2020
10 Loret, AmyGenetic Modifiers of Severity in Collagen VI-Related Muscular DystrophyCollagen VI-related muscular dystrophies (COL6-RD) display phenotypic heterogeneity that includes mild Bethlem myopathy (BM), intermediate (INT), and severe Ullrich congenital muscular dystrophy (UCMD) phenotypes. COL6-RD are characterized by mutations within the collagen VI genes (COL6A1, COL6A2, a...2019
11 Scholes, Connor G.The Ethics of Uncertainty in Clinical Genetics TestingRecent years have seen the explosive development of genetics and its subsequent use in medical practice. In the face of such rapid technological advancement that impacts the health of thousands each year and constitutes a multi-million-dollar industry, ethical analysis of the various shortcomings th...2019
12 Effects of Acute Hypoxia and High pCO2 on Total Protein Content and Metabolic Enzyme Activity in Rockfishes (Sebastes SPP.)Climate change is altering ocean chemistry and wind-driven upwelling regimes. In the California Current System (CCS), these changes are exposing nearshore fishes to increasing levels of high pCO2 and hypoxia. These stressors co-occur during upwelling events, lasting hours to days, and both have the ...2019
13 Fackler, Anderson N.Identification of Kin-20 and UNC-119 Knockout suppressors associated with neuronal development and maintenance in C. elegansNeurons comprise the nervous system-the essential signaling and communication system for nearly all multicellular organisms. To coordinate cells across an entire organism, they must grow to be relatively long. Therefore, neurons extend axons from the cell body. Immature neurons extend growth cones a...2018
14 Hodgson, Keeton R.Accelerating DNA Sequence AlignmentPrecision medicine can provide breakthroughs in current medical technology and treatment. The ability to prescribe a speci#12;c cure to a speci#12;c disease for a spe- ci#12;c person can greatly reduce the cost of medical treatments, reduce mistakes in the medical #12;eld, and increase the e#11;ecti...2018
15 Barbeau, WilliamCharacterization of a New Ribosome Associated Quality Control PathwayProteins are life's double edged sword. Proteins are essential macromolecules of life, and the tasks that some proteins accomplish are quite marvelous. At the same time, if proteins misfold they have the potential to kill the cell that harbors them. It is becoming increasingly clear that proteins ha...Ribosomes - Research2016-12
16 Dart, EmilyDiversity and metabolic potential of microbial communities in a site of continental serpentinizationThe geochemical process of serpentinization releases energy and organic carbon: two of the basic requirements need ed to support life. Sites of active serpentinization in the deep subsurface provide the intriguing possibility of a non-photosynthetically -supported biosphere. However, serpentinizatio...Microbial ecology - Research; Serpentine - Environmental aspects; Gros Morne National Park (N.L.); Syntrophomonadaceae; Serpentinizaiton; Tabeland Ophiolite2016-05
17 Shimko, TylerMapping suppressors of premature sperm activation in C. ElegansThe sperm of the roundworm Caenorhabditis elegans move by a crawling motion, in contrast to mammalian sperm, which exhibit a swimming motion. This method of locomotion makes the sperm of C. elegans an excellent model for examining cell motility. In order to become motile, the sperm must undergo the ...Caenorhabditis elegans -- Spermatozoa; Sperm activation2015-05
18 Walker, KortnieUnderstanding and treating diabetic retinopathyDiabetic retinopathy is a neurovascular disease of the retina and is the leading cause of blindness in the working-age population in the United States. Complications as a result of hyperglycemia and diabetes mellitus (DM) break down the blood-retina barrier (BRB) and retinal vasculature. Current tre...Diabetic retinopathy2015-05
19 Prestgard-Duke, MichaelDynamin localization in Caenorhabditis ElegansDynamin is a 100-KDa GTPase that is essential for endocytosis. The classic model of endocytosis is a sequential mechanism: first, cell membrane is bent and internalized via the formation of a clathrin coat; next, dynamin facilitates GTP hydrolysis, resulting in membrane scission as the newly formed ...Caenorhabditis elegans; Guanosine triphosphatase; Endocytosis2014-05
20 Estrada, JohannaBCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemiaCML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ...Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research2014-04
21 Richards, JacksonChasing channels: Progress in calcium channel localization in the C. Elegans synapseCalcium channels play a crucial role in neurotransmission by facilitating the flow of calcium ions necessary for synaptic vesicle fusion and neurotransmitter release. Different types of calcium channels participate in this process in the neurons of the nematode C. elegans. L- and N-type channels res...Calcium channels; Synaptic vesicles; Caenorhabditis elegans2013-05
22 Auduong, PriscillaSpinal muscular atrophy modeled in drosophila melanogasterSpinal Muscular Atrophy (SMA) is the most commonly inherited cause of death in children (Park, Kariya, & Monani, 2010 for review). This disease is characterized by a loss of motor neurons which leads to muscle degeneration, paralysis, and eventual death by respiratory failure (Monani, 2005 for revie...Spinal muscular atrophy - Research; Drosophila melanogaster - Researcher2012-05
23 Guernsey, MichaelMclr is not solely responsible for pigmentation variation among domestic pigeonsFeather pigmentation in the domesticated rock pigeon, Columba livia, is stunningly diverse. Plumage pigmentation in this, and other, columbid (pigeon and dove) species plays an important role in mate choice and thus is a driving factor in the process of sexual selection. To study the genetic basis o...2012
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