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Creator | Title | Description | Subject | Date |
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Cummins, Heather | Analysis of eyes shut (EYS) function during intestinal regeneration in drosophila melanogaster | The intestine is a self-renewing organ under constant stress. It is the first line of defense against toxins and bacteria and enables digestion and nutrient absorption. Its homeostasis (controlled regulation) plays a critical role in the maintenance of organ function and prevention of tumor generati... | diseases or cancers; homeostasis; sufficient | 2019 |
2 |
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Anderson, Lucius | The transhuman and posthuman in contemporary horror film: a case study for David Cronenberg's crimes of the future | As the uncertain future of humanity's relationship to technology causes widespread apprehension, themes related to transhuman and posthuman theory have begun to appear in the horror genre. By synthesizing posthuman and transhuman philosophy with horror criticism, this project aims to ascertain these... | | 2024 |
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Armstrong, Blair P. | Lower critical solution temperature behavior of elastin-coiled-coil polymer, a potential platform for treatment of non-hodgkin's lymphoma | Non-Hodgkin's lymphoma takes the lives of 20,000 Americans each year. When traditional therapies fail, clinicians have turned to a drug, rituximab, for treatment. However, rituximab is now curative for less than 50% of patients and new treatments are needed. Drug-free macromolecular therapeutics (DF... | | 2021 |
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Hammons, Liam | The lovecraftian chronotope: a formalist analysis of "At the Mountains of madness" | H. P. Lovecraft's fiction has long fascinated critics for the portrayals of cosmic terrors and indescribable monsters. The fiction, however, betrays a common structure and conceit that manifests Lovecraft's ideological and philosophical objectives. This essay applies Mikhail Bakhtin's chronotope the... | | 2021 |
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Jackson, Dale Jay | Aerodynamic mixing losses and discharge coefficients due to film cooling from a symmetric turbine airfoil in transonic flow | Aerodynamic losses and discharge coefficients are obtained for two different Pratt and Whitney axisymetric turbine airfoils with film cooling holes. Blade 3 results are given for the blowing ratios, of 0.42, 0.73, and 1.28. The pressure ratios are 1.18, 1.45, and 2.07 for the "ambient" tests and 1.1... | Mechanical Engineering | 1998-12 |
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Schlegel, Isabelle B. | Peptide-fab conjugates to improve treatment of neovascular age-related macular degeneration | Age-Related Macular Degeneration (AMD), a chronic disease of the eye and leading cause of blindness in Americans over 50, is often treated with agents that inhibit Vascular Endothelial Growth Factor (VEGF). Ranibizumab is an anti-VEGF antibody fragment (Fab) effective at treating over 90% of AMD pat... | | 2021 |
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Lietzke, Stephanie | Removal of endotoxins from recombinant antithrombin | Endotoxins (also known as lipopolysaccharides or ETs) are a pyrogenic byproduct of the breakdown of gram-negative bacterial cell-walls, such as E. coli. They cause fever and septic shock in humans, and are therefore highly regulated by the FDA and USP. ETs are a common contaminant in recombinant pr... | Endotoxins - Research; Antithrombins - Therapeutic use; Sheep as laboratory animals - Research; endotoxin removal; Angiogenesis | 2016-04 |
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Hatch, Kyleigh M. | Gender differences in the correlations between mobile personal financial management technology and financial outcomes | | | 2021 |
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Larson, Brooke | Chacterization of signaling to the degradative pathways of the cell | Protein degradation in cells is a complex network of pathways that are distinct from each other but highly interconnected. Understanding how proteins are degraded in cells is important for understanding and developing treatments for diseases such as lysosomal storage diseases and neurodegenerative d... | | 2023 |
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Peterson, John | Potential Therapeutic Inhibition of Epigenetic Modulator LSDI in Glioblastoma Multiforme | Glioblastoma (GBM) is the most common primary brain tumor in adults, and while advances in surgery, radiation, and standard chemotherapies have improved survival in this disease marginally over the years, the outcomes for most patients remain disappointing (Bhat, 2013). Recent studies have identifie... | | |
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Munn, Jackson | Determining microbial community composition and methane flux or red butte canyon sediment over time | Methane is a potent greenhouse gas that is released from the soil into the atmosphere, which contributes heavily to global warming. One potential way of reducing the amount of methane in the air is through studying methane consuming bacteria (methanotrophs) and how they interact with other microbes ... | | 2022 |
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Leyendecker, Peyton | Unraveling the Q system function in prokaryotes | Expanding the prokaryotic synthetic biology toolbox is a promising strategy for enhancing control of gene expression. More specifically, understanding the eukaryotic Q system activation of the T7 promoter in prokaryotes can enable enhanced engineering applications for research and biomedicine. Here,... | | 2024 |
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Nazarenko, Elena | Current and future financial wellbeing of old age Russian pensioners | This paper compares pensioners' income with cost of living and subsistence minimum level to gauge financial wellbeing of pensioners. Using data from Russia Longitudinal Monitoring survey (RLMS-HSE), I formally test whether pensioners' income covers the cost of living across five regions: Moscow, Sai... | Old age pensions -- Russia; Retirees -- Russia -- Economic conditions | 2015-03 |
14 |
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Verhaaren, Molly | Double-checking: a statistical analysis of twenty-first century U.S. election recounts | Election recounts are an integral part of voting history in the United States. Initiated by the political jurisdiction or by the candidate, they have the power to overturn previously decided election results and have done so on more than one occasion. However, that power may not be worth its price a... | | 2021 |
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Karahalios, Vasiliki | The Unassuming Subversion of Jacksonian-ERA Democracy: An Analysis of Mary Edmonia Lewis's Minnehaha and Hiawatha of 1868 | By the mid-nineteenth century, Henry Wadsworth Longfellow had become one of the most celebrated poets in the United States. The publication of his poem The Song of Hiawatha in 1855 established him as the great American epic poet of the 19th-century. Not only was The Song of Hiawatha widely read and ... | | 2019 |
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Kasera, Shalini | Effect of IUGR and supplemental DHA on molecular mediators of hepatic lipid accumulation in the rat | Intrauterine growth restriction (IUGR) refers to failure of the fetus to achieve its genetic growth potential in utero and is commonly caused by uteroplacental insufficiency secondary to maternal hypertensive disorders. A hallmark of IUGR is a decrease in circulating docosahexaenoic acid (DHA), an �... | | 2022 |
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Hansen, Mason | Interferon gamma inducible nampt and its role in resisting cancer cell growth | The tumor microenvironment (TME) is very complex and important due to its ability to influence the response of therapies on tumors. Immune cells infiltrate the TME and secrete inflammatory cytokines, such as interferon-gamma (IFNg), which help activate the immune system. This activation leads to an ... | | 2023 |
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Dove-Swisher, Taylor | Bias-Coppected Estimation for singles-event studies | Single-firm event studies used in securities fraud litigation are prone to statistical bias. Brav and Heaton (2015) describe three potential issues: low statistical power to detect price impacts, confounding effects that cannot be averaged out, and an effect bias in the upward direction. The effect ... | | 2017 |
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Tanner, Trevor | The automation of a discontinuous membrane extruder | One quarter of American troop deaths in the Middle East were classified as "potentially survivable." Of these, over 90 percent of the battlefield deaths and over 80 percent of the deaths in treatment centers were attributed to one factor: blood loss. Blood's limited supply, short half-life, and r... | Blood - Transfusion - Research; Membrane homogenization; Synthetic blood; Artificial oxygen carriers | 2016-05 |
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Boyd, Taylor Alexis | Homeostatic plasticity in inherited eye disease | Retinitis Pigmentosa is rare inherited retinal disease that causes progressive blindness as an affected individual ages. Blindness is a significant public health issue, and visual impairment, especially when varying over the lifespan, can have immense impact on community health. For my honors thesis... | | 2021 |
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Worms, Katherine | Paleoredox Conditions, Paleoproductivity, and Depositional Environment of an Eocene Black Shale: Mahogany Zone, Green River Formation, Eastern Uinta Basin, Utah | Black shales are commonly assumed to record anoxic, organically productive paleoenvironments. The Mahogany zone of the early Eocene Green River Formation is a classic example of an organic-rich black shale. It is thought to record a period of high ancient lake level conditions in which elevated alga... | | 2019 |
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Scamfer, Sierra | Studying pancreatic acinar cell differentiation through transcription factor reprogramming | Pancreatic ductal adenocarcinoma is a highly lethal human cancer that originates from acinar cells in the pancreas. Ptf1a is a transcription factor that plays an important role in the development of the pancreas and in the differentiation and maintenance of acinar cells. Ptf1a expression is lost dur... | | 2021 |
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Pecchia-Bekkum, Annika | Applications of controlled DNA assembly and disassembly in biosensing and responsive drug delivery | Deoxyribonucleic acid (DNA) provides many exciting functions outside of simply encoding genetic information. Herein, we report two techniques to control the assembly and disassembly of nucleic acids. Within these techniques, DNA is used as a programmable material for biosensing and drug delivery. In... | Nucleic acids; biotechnology | 2013-08 |
24 |
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Wiese, Claudia | DNA metabarcoding of trnL intron using the minion device to assess BEE foraging from Pollen | In recent decades many bee species, including Apis mellifera (European honeybee), have experienced worldwide population declines. In this paper we tested a novel molecular approach to evaluate foraging of A. mellifera Specifically, we sequenced trnL (UAA) intron DNA barcodes from isolated pollen fro... | | 2023 |
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Ruan, Ting | Endogenous ceramide contributes to cardiovascular complications in Type II diabetes by decreasing the association between PP2A and I2PP2A | Cardiovascular complications are the leading cause of death in individuals with conditions associated with insulin resistance, e.g. type 2 diabetes, diet-induced obesity. In patients with type 2 diabetes, cardiovascular complications are 2-4 times more prevalent. One common cardiovascular complicati... | Ceramides - Physiological effect; Diabetic angiopathies | 2014 |