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Leber's Optic Neuropathy (PowerPoint) | AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology Society | Several Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation. | Leber's Optic Neuropathy |