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1 Kerber, Richard A.A genome-wide study replicates linkage of 3p22-24 to extreme longevity in humans and identifies possible additional lociBackground: Although there is abundant evidence that human longevity is heritable, efforts to map loci responsible for variation in human lifespan have had limited success. Methodology/Principal Findings: We identified individuals from a large multigenerational population database (the Utah Populati...2012-01-01
2 Kestle, John R. W.Abdominal bindersSklar and colleagues2 describe their experience managing "over-shunting headaches" with an abdominal binder. Seventy children with over-shunting headaches complied with application of a binder for about 1 month. In 61 patients (87%), the headaches "greatly improved or went away." This headache relie...2012-01-01
3 Light, Alan R.Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathwayProtein tyrosine phosphorylation has been implicated in normal and pathological functions, such as cell proliferation, migration and differentiation. Recently, some studies have shown that Src family kinases (SFKs) were involved in neurological disorders and neuropathic pain states in which microgli...2012-01-01
4 Normann, Richard A.Adaptive parameter selection for asynchronous intrafascicular multi-electrode stimulationThis paper describes an adaptive algorithm for selecting perelectrode stimulus intensities and inter-electrode stimulation phasing to achieve desired isometric plantar-flexion forces via asynchronous, intrafascicular multi-electrode stimulation. The algorithm employed a linear model of force product...2012-01-01
5 Litwin, Christine M.Anti-tuberculosis IgG antibodies as a marker of active mycobacterium tuberculosis diseaseAnti-Mycobacterium tuberculosis IgG antibodies may aid in the diagnosis of active M. tuberculosis disease. We studied whether anti-M. tuberculosis IgG antibodies are elevated in active M. tuberculosis disease and assessed factors contributing to false positive and negative results. A retrospective s...2012-01-01
6 Light, Alan R.ASICs do not play a role in maintaining hyperalgesia induced by repeated intramuscular acid injectionsRepeated intramuscular acid injections produce long-lasting mechanical hyperalgesia that depends on activation of ASICs. The present study investigated if pH-activated currents in sensory neurons innervating muscle were altered in response to repeated acid injections, and if blockade of ASICs revers...2012-01-01
7 Schmidt, Meic H.Cervical spine metastases: techniques for anterior reconstruction and stabilizationThe surgical management of cervical spine metastases continues to evolve and improve. The authors provide an overview of the various techniques for anterior reconstruction and stabilization of the subaxial cervical spine after corpectomy for spinal metastases. Vertebral body reconstruction can be ac...2012-01-01
8 Bisson, Erica F.Computed tomography-based determination of a safe trajectory for placement of transarticular facet screws in the subaxial cervical spine: Clinical articleObject. Placement of transarticular facet screws is one option for stabilization of the subaxial cervical spine. Small clinical series and biomechanical data support their role as a substitute for other posterior stabilization techniques; however, the application of transarticular facet screws in th...2012-01-01
9 Bisson, Erica F.Cost effectiveness of subaxial fusion-lateral mass screws versus transarticular facet screwsAs health care reform continues to evolve, demonstrating the cost effectiveness of spinal fusion procedures will be of critical value. Posterior subaxial cervical fusion with lateral mass screw and rod instrumentation is a wellestablished fixation technique. Subaxial transarticular facet fixation is...2012-01-01
10 Thomas, Kirk R.Cytochrome P450 2B diversity and dietary novelty in the herbivorous, desert woodrat (Neotoma lepida)Detoxification enzymes play a key role in plant-herbivore interactions, contributing to the on-going evolution of ecosystem functional diversity. Mammalian detoxification systems have been well studied by the medical and pharmacological industries to understand human drug metabolism; however, little...2012-01-01
11 Couldwell, William T.Delayed vasospasm after removal of a skull base meningiomaCerebral vasospasm is a well-known clinical entity associated with subarachnoid hemorrhage and traumatic brain injury [1,2]. In rare instances, vasospasm has been reported to occur after tumor resections, more specifically, after skull base tumor removal [3-5]. We report a rare case of a patient pre...2012-01-01
12 Moshirfar, MajidDouble-pass microkeratome technique for ultra-thin graft preparation in Descemet's stripping automated endothelial keratoplastyEndothelial keratoplasty is evolving with increased attention placed on the optical qualities of the posterior donor lenticule. In efforts to improve visual outcomes, the effects of the thickness, smoothness, and planar profile are being studied. This paper describes a double-pass microkeratome tech...2012-01-01
13 Moshirfar, MajidThe effect of preoperative keratometry on visual outcomes after moderate myopic LASIKThe relationship between preoperative keratometry (K) and visual outcomes in laser-assisted in situ keratomileusis (LASIK) has been studied in high myopia and hyperopia, but not in moderate myopia. Rao et al report increased undercorrection in eyes with preoperative spherical equivalent (SE) of −1...2012-01-01
14 Couldwell, William T.Efficacy of clip-wrapping in treatment of complex pediatric aneurysmsPurpose: Pediatric aneurysms (PAs) are distinct from their adult counterparts with respect to typical location, aneurysm type, and known predisposing risk factors. Many strategies have been employed to treat PAs, but, although it has been used frequently in adults, clip-wrapping in pediatric patient...2012-01-01
15 Madsen, Troy EdwardEmergency medicine resident anesthesia training in a private vs. academic settingAirway management is an essential part of any Emergency Medicine (EM) training program. Academic centers typically provide training to many learners at various training levels in a number of medical specialties during anesthesiology rotations. This potentially creates competition for intubation proc...2012-01-01
16 Fuhrmann, SabineExtraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafishDorsal retinal fate is established early in eye development, via expression of spatially restricted dorsal‐specific transcription factors in the optic vesicle; yet the events leading to initiation of dorsal fate are not clear. We hypothesized that induction of dorsal fate would require an extraocu...2012-01-01
17 Couldwell, William T.The frontotemporal (Pterional) approach: an historical perspectiveThe frontotemporal, so-called "pterional" approach has evolved with the contribution of many neurosurgeons over the past century. It has stood the test of time and been the most commonly used transcranial approach in neurosurgery. In its current form, drilling the sphenoid wing as far down as the su...2012-01-01
18 Light, Alan R.Functional properties of tooth pulp neurons responding to thermal stimulationThe response properties of tooth pulp neurons that respond to noxious thermal stimulation of the dental pulp have been not well studied. The present study was designed to characterize the response properties of tooth pulp neurons to noxious thermal stimulation of the dental pulp. Experiments were c...2012-01-01
19 Couldwell, William T.Ganglion cyst of the temporomandibular joint with intracranial extension in a patient presenting with seventh cranial nerve palsyGanglion cysts arising from the temporomandibular joint are rare entities that often present with swelling and minimal to no pain in the preauricular region. To the Author's? knowledge, a temporomandibular joint ganglion cyst occurring with acute facial nerve palsy and intracranial extension has ne...2012
20 Couldwell, William T.Giant pituitary tumor combined approachNishioka et al. have provided a review of 29 patients with large pituitary adenomas who underwent surgery through a simultaneous transsphenoidal and transcranial approach at their institution during a 7-year period. Large adenomas with hourglass constriction, complex lobulations, and asymmetric exte...2012-01-01
21 Lucero, Mary T.Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo2012-01-01
22 Teerlink, Craig CarlHeritability of facial appearance2012
23 Crockett, David K.Identification of histoplasma -specific peptides in human urineHistoplasmosis is a severe dimorphic fungus infection, which is often difficult to diagnose due to similarity in symptoms to other diseases and lack of specific diagnostic tests. Urine samples from histoplasma-antigen-positive patients and appropriate controls were prepared using various sample prep...2012-01-01
24 Garber, SarahImage guidance for brain metastases resectionThe primary goal in removing a metastatic brain tumor is to maximize surgical resection while minimizing the risk of neurological injury. Intraoperative image guidance is frequently used in the resection of both primary and metastatic brain tumors. Stereotactic volumetric techniques allow for smalle...2012-01-01
25 Narus, Scott P.Improving access to longitudinal patient health information within an emergency departmentWe designed and implemented an electronic patient tracking system with improved user authentication and patient selection. We then measured access to clinical information from previous clinical encounters before and after implementation of the system. Clinicians accessed longitudinal information for...2012-01-01
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