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1 Couldwell, William T.Thrombosed Basilar Apex Aneurysm presenting as a third ventricular mass and hydrocephalus: case report and review of the literatureAneurysms presenting as third ventricular masses are uncommon; most are giant aneurysms arising from the basilar apex. We present a case of a thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalus in a 55-year-old man. The case is unique in the literature as the an...Basilar Apex Aneurysm; Ventricular Mass; Third Ventriculostomy2005-04
2 Couldwell, William T.Thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalusAneurysms presenting as third ventricular masses are uncommon; most are giant aneurysms arising from the basilar apex. We present a case of a thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalus in a 55-year-old man. The case is unique in the literature as the an...Basilar apex aneurysm; Ventricular mass; Third ventriculostomy2005
3 Couldwell, William T.Management of cysticercosis cerebriInfestation of the central nervous system (CNS) with the parasitic larval form of the cestode Taenia solium, Cysticercosis Cerebri represents an endemic problem in much of the underdeveloped world. In such areas, up to 4% of the population maybe affected by neurocysticercosis, and it accounts for u...Taenia solium; Cysticercosis Cerebri; Parenchymal cyst; Basilar cisternal cyst; Intraventricular cyst1989
4 Couldwell, William T.Experience with use of extended length peritoneal shunt cathetersThe placement of a ventriculoperitoneal (VP) shunt is the current treatment of choice for diversion of cerebrospinal fluid associated with hydrocephalus. Although there are a host of reported potential abdominal complications related to the procedure, they are notably uncommon. The authors report t...1996
5 Kestle, John R. W.Propionibacterium encephalitis [Letter to the editor]To THE EDITOR: We read with interest the article by Camarata, et al., reporting two cases of dorsal midbrain encephalitis (Camarata PJ, McGeachie RE, Haines S J: Dorsal midbrain encephalitis caused by Propionibacterium aches. Report of two cases. J Neurosurg 72." 654-659, April, 1990). There are...1990
6 Couldwell, William T.; House, Paul A.; Salzman, Karen L.; Osborne, Anne G.; MacDonald, Joel D.; Jensen, Randy L.Surgical considerations regarding giant dilations of the perivascular spacesObject. Dilations of brain perivascular spaces (PVSs), also known as Virchow-Robin spaces, are routinely identified on magnetic resonance imaging studies of the brain and recognized as benign normal variants. Giant dilations occur only rarely and can be easily misdiagnosed as central nervous system ...2004
7 Couldwell, William T.Definition of the role of contemporary surgical management in cisternal and parenchymatous cysticercosis cerebriWith increasing immigration from endemic regions, the incidence of neurocysticercosis in North America is rising. This retrospective study was undertaken to examine the role of surgery in those cases presenting with large cystic parenchymal and cisternal lesions in the current era of anthelminthic a...Brain cyst; Computed tomography; Neurocysticercosis; Magnetic resonance imaging; Praziquantel; Stereotaxis1991
8 Garber, SarahSpinal arteriovenous fistulas in children with hereditary hemorrhagic telangiectasia: report of 2 casesHereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant angiodysplasia with high penetrance and variable expression. The manifestations of HHT are often age related, and spinal arteriovenous fistula (AVF) may be the initial presentation of HHT in young children. Because spinal AVFs are...2012-01-01
9 Schmidt, Meic H.Diagnosis and management of sacral Tarlov cystsPerineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com...Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome2003
10 Kestle, John R. W.Assessing the validity of the endoscopic shunt insertion trial: did surgical experience affect the results?Object. Most surgical procedures are associated with a learning curve in which the success rate is lower early in the experience before mistakes have been identified and modifications made to the procedure. Negative results obtained early in a trial's learning curve may be a matter of timing rather ...Endoscopic shunt insertion; Ventriculoperitoneal shunt; Pediatric neurosurgery; Surgical experience2004-01-01
11 Kestle, John R. W.; MacDonald, Joel D.; Schmidt, Richard H.Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhageObject. Cerebral vasospasm after subarachnoid hemorrhage (SAH) continues to be a major source of morbidity in patients despite significant clinical and basic science research. Efforts to prevent vasospasm by removing spasmogens from the subarachnoid space have produced mixed results. The authors hyp...Cerebral vasospasm; Lumbar drainage2004
12 Schmidt, Meic H.; Couldwell, William T.Far lateral transcondylar transtubercular approach to lesions of the ventral foramen magnum and craniovertebral junctionThe craniovertebral junction, which consists of the lower one third of the clivus, the foramen magnum, and the CI and C2 vertebrae, is a common site for neoplastic, vascular, congenital, and degenerative lesions of the cranial base. The far lateral transcondylar transtubercular approach (commonlyr...Far-lateral; Transcondylar; Transtubercular; Ventral foramen magnum; Craniovertebral junction2007
13 Couldwell, William T.Far-lateral transcondylar approach: surgical technique and its application in neurenteric cysts of the cervicomedullary junctionNeurenteric cysts are rare benign lesions of the central nervous system that are lined by endodermal cell-derived epithelium. Although they occur mostly in the spine, they can occur intracranially, most often in the posterior fossa. Neurenteric cysts that are located in the anterior cervicomedullary...2005
14 House, Paul A.; Couldwell, William T.De novo fenestration of the optic nerve case illustration.Fenestration of the optic nerve or chiasm due to the presence of aneurismal dilation of the internal carotid artery (ICA) has been described. In three out of five cases reviewed recently, the optic nerve was penetrated by an ICAΓÇôophthalmic artery aneurysm.3 Penetration of the optic nerve was du...Aneurysm; Congenital Optic Nerve2005-02-01
15 Garber, SarahImage guidance for brain metastases resectionThe primary goal in removing a metastatic brain tumor is to maximize surgical resection while minimizing the risk of neurological injury. Intraoperative image guidance is frequently used in the resection of both primary and metastatic brain tumors. Stereotactic volumetric techniques allow for smalle...2012-01-01
16 Kestle, John R. W.Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalusOBJECTIVE: Forty percent of standard cerebrospinal fluid shunts implanted for the treatment of pediatric hydrocephalus fail within the first year. Two new shunt valves designed to limit excess flow, particularly in upright positions, were studied to compare treatment failure rates with those for st...Shunt failure; Valve design; Orbis-Sigma valve; Delta valve1998
17 Couldwell, William T.Management of meningiomas involving the transverse or sigmoid sinusMeningiomas that invade the transverse or sigmoid sinuses are uncommon tumors that are challenging to treat surgically. Although the risk of recurrence is associated with the extent of resection, complete removal of meningiomas in these locations must be balanced with avoidance of venous outflow obs...2013-01-01
18 Capecchi, Mario R.Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebraeTo address the expression and function of Hoxb13, the 5' most Hox gene in the HoxB cluster, we have generated mice with loss-of-function and beta-galactosidase reporter insertion alleles of this gene. Mice homozygous for Hoxb13 loss-of-function mutations show overgrowth in all major structures deriv...Animals; Axons; Ganglia, Spinal; Mice; Spinal Cord2003-04-15
19 Kestle, John R. W.Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshopObject. Treatment for hydrocephalus has not advanced appreciably since the advent of cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that clinical and basic research could address, which in turn could improve therapeutic options. To clarify the main issues facing hydr...Biomedical research2007
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