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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Narus, Scott P. | A domain analysis model for eIRB systems: addressing the weak link in clinical research informatics | Institutional Review Boards (IRBs) are a critical component of clinical research and can become a significant bottleneck due to the dramatic increase, in both volume and complexity of clinical research. Despite the interest in developing clinical research informatics (CRI) systems and supporting dat... | 2014-01-01 | |
| 2 |
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Bernstein, Paul S.; Zabriskie, Norman A.; Zhang, Kang | CFH Y402H Confers similar risk of soft Drusen and both forms of advanced AMD | BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that lead to loss of central vision. S... | 2005 | |
| 3 |
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Gesteland, Raymond F.; Wills, Norma M.; Atkins, John F. | Comparative studies of frameshifting and nonframeshifting RNA pseudoknots: a mutational and NMR investigation of pseudoknots derived from the bacteriophage T2 gene 32 mRNA and the retroviral gag-pro frameshift site | Mutational and NMR methods were used to investigate features of sequence, structure, and dynamics that are associated with the ability of a pseudoknot to stimulate a "1 frameshift. In vitro frameshift assays were performed on retroviral gag-pro frameshift-stimulating pseudoknots and their derivati... | Frameshifting; NMR; Pseudoknot; Retrovirus | 2002 |
| 4 |
 |
Digre, Kathleen B.; Warner, Judith E. A.; Bernstein, Paul S.; Alder, Stephen C. | Vitamin A in the cerebrospinal fluid of patients with and without idiopathic intracranial hypertension | We quantified vitamin A in the cerebrospinal fluid of patients with idiopathic intracranial hypertension, elevated intracranial pressure of other causes and normal intracranial pressure. Vitamin A could be detected by high-pressure liquid chromatography in most of the specimens. There was a signific... | Chromatography, High Pressure Liquid; Headache | 2002-11 |
| 5 |
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Gesteland, Raymond F.; Atkins, John F.; Howard, Michael T. | Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides | Evidence is presented that morpholino, 2_x0001_-O-methyl, phosphorothioate, and RNA antisense oligonucleotides can direct sitespecific âˆ'1 translational frameshifting when annealed to mRNA downstream from sequences where the P- and A-site tRNAs are both capable of re-pairing with âˆ'1 frame c... | Recoding; Frameshifting; Antisense; Morpholino; Phosphorothioate; 2_x0001_-O-methyl | 2004 |
| 6 |
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Francis, Leslie | Penn Central Transportation Company v. New York City: easy taking-clause cases make uncertain Law. | In Penn Central Transportation Company v. New York City, the Supreme Court held that New York City's Landmarks Preservation Law as applied to Grand Central Terminal was not a "taking" of property for which compensation is constitutionally required. The decision has been hailed as a major victory for... | Law; Compensation; Property Rights; Landmarks Preservation Law; Supreme Court Rulings | 2006-06-16 |
| 7 |
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Zhang, Kang | New locus for autosomal dominant stargardt-like disease maps to chromosome 4 | Stargardt disease (STGD) is the most common hereditary macular dystrophy and is characterized by decreased central vision, atrophy of the macula and underlying retinal-pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina. STGD is most commonly inherited a... | Haplotypes; Genetic Markers | 1999 |
| 8 |
 |
Gesteland, Raymond F.; Atkins, John F.; Felden, Brice; McCutcheon, John P. | Probing the structure of the Escherichia coli 10Sa RNA (tmRNA) | The conformation of the Escherichia coli 10Sa RNA (tmRNA) in solution was investigated using chemical and enzymatic probes. Single- and double-stranded domains were identified by hydrolysis of tmRNA in imidazole buffer and by lead(II)-induced cleavages. Ribonucleases T1 and S1 were used to map unpai... | Covariation; Pseudoknot; Structural Probing; 10Sa RNA; tmRNA | 1997 |
| 9 |
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Couldwell, William T. | Transnasal excerebration surgery in ancient Egypt: Historical vignette | Ancient Egyptians were pioneers in many fields, including medicine and surgery. Our modern knowledge of anatomy, pathology, and surgical techniques stems from discoveries and observations made by Egyptian physicians and embalmers. In the realm of neurosurgery, ancient Egyptians were the first to elu... | 2012-01-01 | |
| 10 |
 |
Francis, Leslie | Eminent domain compensation in the Western states: a critique of the fair market value model | Both the United States Constitution and the constitutions of the states of the intermountain west and the Pacific Coast prohibit the state from taking property without paying just compensation. Thus, there are two basic issues in any eminent domain case. First, has governmental interference with pro... | Eminent domain; Compensation; Governmental interference; Fair Market Value | 2006-06-16 |
| 11 |
 |
Pepper, Ginette A. | Improving geriatric drug therapy. | Healthcare professional and society in general harbor ambivalent beliefs about drug therapy. Most of us anticipate that drugs will eventually control, or even cure many age-related diseases. On the other hand, there is a growing unease about the hazards of medications, which range from minor discomf... | Older people | 1987-10 |
| 12 |
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Warner, Homer R. | A Computer-Based Diagnostic Model for Individual Case Review | Biomedical Informatics | 1995 | |
| 13 |
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Light, Alan R. | Functional properties of tooth pulp neurons responding to thermal stimulation | The response properties of tooth pulp neurons that respond to noxious thermal stimulation of the dental pulp have been not well studied. The present study was designed to characterize the response properties of tooth pulp neurons to noxious thermal stimulation of the dental pulp. Experiments were c... | 2012-01-01 | |
| 14 |
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Gesteland, Raymond F.; Atkins, John F. | Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expression | Translating ribosomes can shift reading frame at specific sites with high efficiency for gene expression purposes. The most common type of shift to the 1 frame involves a tandem realignment of two anticodons from pairing with mRNA sequence of the form X XXY YYZ to XXX YYY Z where the spaces indicate... | 1 frameshifting; 39 context effect; Codon anticodon interaction; Escherichia coli ; Recoding; tRNALys; XXXY YYZ frameshift motifs | 2002 |
| 15 |
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Warner, Homer R. | The Characteristic Sequence for the Onset of Contraction in the Normal Human Left Ventricle | Biomedical Informatics | 1979 | |
| 16 |
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Bernstein, Paul S. | Evaluation of the G protein coupled receptor-75 (GPR75) in age related macular degeneration | 2001 | ||
| 17 |
 |
Dailey, Andrew T. | Emergent aneurysm clipping without angiography in the moribund patient with intracerebral hemorrhage: the use of infusion computed tomography scans | THE AUTHORS REPORT their experience with 25 patients (mean age, 44.3 ± 12.1 years) with an intracerebral hematoma (ICH) from a ruptured aneurysm who were emergently operated on without angiography. Instead, preoperative high-resolution infusion computed tomography (CT) scans were used to identify... | Ruptured aneurysms; Computed tomography; Infusion computed tomography; Aneurysm clipping | 1993 |
| 18 |
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Blumenthal, Donald K.; Trewhella, Jill | Conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding. | Different isoforms of the full-length protein kinase A (PKA) regulatory subunit homodimer (R2) and the catalytic (C) subunit-bound holoenzyme (R2C2) have very different global structures despite similar molecular weights and domain organization within their primary sequences. To date, it has been th... | Protein Isoforms; Global Structures; cAMP | 2005-10-21 |
| 19 |
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Couldwell, William T. | Expanding neurosurgery | The history of medicine is replete with innovations in neurosurgery that have spurred further developments across the medical spectrum. Surgeons treating pathologies in the head and spine have broken ground with new approaches, techniques, and technologies since ancient times. Neurosurgeons occupy a... | 2014-01-01 |
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