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Creator | Title | Description | Subject | Date |
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Normann, Richard A. | Visual Neuroprosthetics: Functional Vision for the Blind | Resent progress in materials and microfabrication technologies have allowed researchers to reconsider the prospect of providing a useful visual sense to the profoundly blind. This will be accomplished by electrically stimulating their visual systems via an array of implanted microelectrodes. T... | Visual Neuroprosthetics; Vision; Blindness | 1995-01 |
| 2 |
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Normann, Richard A.; Maynard, Edwin M. | Neural interface for a cortical vision prosthesis | The development of a cortically based vision prosthesis has been hampered by a lack of basic experiments on phosphene psychophysics. This basic research has been hampered by the lack of a means to safely stimulate large numbers of cortical neurons. Recently, a number of laboratories have developed a... | Neuroprosthetics; Artificial Vision; Electrode Arrays; Multielectrode Recordings; Biocompatibility | 1999 |
| 3 |
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Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | Mobility performance with a pixelized vision system | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
| 4 |
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Angelucci, Alessandra; Lund, Jennifer S. | Circuits for local and global signal integration in primary visual cortex | Contrast-dependent changes in spatial summation and contextual modulation of primary visual cortex (V1) neuron responses to stimulation of their receptive field reveal long-distance integration of visual signals within V1, well beyond the classical receptive field (cRF) of single neurons. To identif... | Primary Visual Cortex; Extrastriate Cortex; Feed-back Connections; Lateral Connections; SUrround Modulation; Macaque | 2002-10-01 |
| 5 |
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Angelucci, Alessandra | Multiple components of surround modulation in primary visual cortex: Multiple neural circuits with multiple functions? | The responses of neurons in primary visual cortex (V1) to stimulation of their receptive field (RF) are modulated by stimuli in the RF surround. This modulation is suppressive when the stimuli in the RF and surround are of similar orientation, but less suppressive or facilitatory when they are cross... | | 2014-01-01 |
| 6 |
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Angelucci, Alessandra | Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis. | The spatial relations between selected classes of association and callosal neurons were studied in the frontal and parietal lobes of the macaque monkey using retrogradely transported fluorescent dyes. Fast blue and nuclear yellow were injected in the left frontal (areas 4 and 6) and right posterior ... | Macaca fascicularis; Parietal Lobe; Neurons | 1989 |
| 7 |
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Normann, Richard A.; Maynard, Edwin M. | Neuronal interactions improve cortical population coding of movement direction | Interactions among groups of neurons in primary motor cortex (MI) may convey information about motor behavior. We investigated the information carried by interactions in MI of macaque monkeys using a novel multielectrode array to record simultaneously from 12-16 neurons during an arm-reaching task. ... | Motor Cortex; Monkey; Population Coding; Movement | 1999 |
| 8 |
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Normann, Richard A. | Functional reorganization of primary visual cortex induced by electrical stimulation in the cat. | Compared to the high degree of plasticity observed in a juvenile, mature sensory cortices have long been held to be immutable but, recently, researchers have suggested some plasticity persists in the mature cortex. Cortical reorganization has particular saliency to the development of a cortically ba... | Cat; Electrophysiology; Phosphene; Plasticity; Receptive Field; Striate Cortex | 2005 |
| 9 |
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Angelucci, Alessandra | Layer-specific programs of development in neocortical projection neurons | How are long-range axonal projections from the cerebral cortex orchestrated during development? By using both passively and actively transported axonal tracers in fetal and postnatal ferrets, we have analyzed the development of projections from the cortex to a number of thalamic nuclei. We report th... | Axonal Transport; Efferent Pathways; Brain Mapping | 1995 |
| 10 |
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Normann, Richard A.; Campbell, Patrick K.; Jones, Kelly E.; Huber, Robert J.; Horch, Kenneth W. | Silicon-based, three-dimensional neural interface: manufacturing processes for an intracortical electrode array | A method has been developed for the manufacture of a "three-dimensional" electrode array geometry for chronic intracortical stimulation. This silicon based array consists of a 4.2 x 4.2 x 0.12 mm thick monocrystalline substrate, from which project 100 conductive, silicon needles sharpened to facilit... | Electric Stimulation; Electrodes, Implanted; Sensory Cortex; Intracortical Electrode Array | 1991 |
| 11 |
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Olson, Randall J.; Coldwell, Karin D.; Compton, Bruce J.; Giddings, John C. | Sedimentation field-flow fractionation: a method for studying particulates in cataractous lens | It is shown that the technique of sedimentation field-flow fractionation (sedimentation [sed] FFF) can be used to determine the particle content and particle size distribution of normal and cataractous lenses. A 31-year-old normal human lens, for example, showed a particle content of 1.5% by weight ... | Fractionation; Cataractous Lens; Particulates | 1984 |
| 12 |
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Olson, Randall J. | Clinical experience with 21-gauge manual microphacoemulsification using Sovereign WhiteStar Technology in eyes with dense cataract | PURPOSE: To present a series of patients who had 21-gauge microphacoemulsification using Sovereign WhiteStar technology. SETTING: John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, USA. METHODS: Eighteen consecutive patients with cataracts judged to be 3+ or 4+ on... | Cataract; Microsurgery; Phacoemulsification; Postoperative Complications; Visual Acuity | 2004-01 |
| 13 |
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Normann, Richard A.; Shah, Maulik R. | Study of printed spiral coils for neuroprosthetic transcranial telemetry applications | We have explored the use of printed spiral coils (PSC's) for neuroprosthetic transcranial telemetry applications. We fabricated two-dimensional PSC's on a thin (25 microns) polyimide substrate using copper (35 microns) as a conducting material. All the coils had a fixed inner diameter of 1.0 cm. We ... | Blindness; Neuroprosthesis; Transcranial Telemetry System; Prosthesis Design | 1998 |
| 14 |
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Angelucci, Alessandra | Experimentally induced retinal projections to the ferret auditory thalamus: development of clustered eye-specific patterns in a novel target | We have examined the relative role of afferents and targets in pattern formation using a novel preparation, in which retinal projections in ferrets are induced to innervate the medial geniculate nucleus (MGN). We find that retinal projections to the MGN are arranged in scattered clusters. Clusters a... | Retina; Ferrets | 1997 |
| 15 |
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Angelucci, Alessandra | Role for nitric oxide in the development of the ferret retinogeniculate projection | The ferret retinogeniculate projection segregates into eye-specific layers during the first postnatal week and into ON/OFF sublaminae, which receive inputs from either on-center or off-center retinal ganglion cells, during the third and fourth postnatal weeks. The restriction of retinogeniculate axo... | Enzyme Inhibitors; Visual Pathways; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 1996 |
| 16 |
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Digre, Kathleen B.; Skuster, Denise Z. | Neurologic conditions presenting as psychiatric disorders. | Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit... | Psychiatric Diagnosis; Neurologic Disease | 1992-06-15 |
| 17 |
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Normann, Richard A.; Jones, Kelly E. | Advanced demultiplexing system for physiological stimulation | A CMOS very large scale integration (VLSI) chip has been designed and built to implement a scheme developed for multiplexing/demultiplexing the signals required to operate an intracortical stimulating electrode array. Because the use of radio telemetry in a proposed system utilizing this chip may im... | Electrode Array; Stimulation; Telemetry; Microelectrodes; Transistors | 1997 |
| 18 |
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Sung, Younghoon; Kondo, Douglas Gavin; Jeong, Eun-Kee; Renshaw, Perry Franklin | Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder | Introduction. This paper focuses on the application of Magnetic Resonance Spectroscopy (MRS) to the study of Major Depressive Disorder (MDD) in children and adolescents. Method. A literature search using the National Institutes of Health?s PubMed database was conducted to identify indexed peer-revie... | | 2011 |
| 19 |
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Crandall, Alan S. | Torn posterior capsule: prevention, recognition and management | Modern cataract surgery performed with phacoemulsification allows meticulous intraocular control and minimal incision size, but has the inherent risk of capsular rupture. Therefore, surgeons performing cataract surgery will inevitably face the complication of a torn posterior capsule. Torn posteri... | Capsulorrhexis complications; Phacoemulsification; Posterior capsular tears; Shallow anterior chamber; Suprachoroidal hemorrhage; Vitrectomy | 1999 |
| 20 |
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Schmidt, Meic H. | Is vertebral augmentation the right choice for cancer patients with painful vertebral compression fractures? | Cancer-related fractures of the spine are different from osteoporotic ones, not only in pathogenesis but also in natural history and treatment. Higher class evidence now supports offering balloon kyphoplasty to a patient with cancer, provided that the pain is significant in intensity, has a position... | | 2012-01-01 |
| 21 |
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Baehr, Wolfgang | Tissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding protein | Interphotoreceptor retinoid-binding protein (IRBP) is an extracellular protein that has been suggested to participate in the visual process as a carrier for visual retinoids. A chimeric gene composed of the human IRBP promoter fused to the bacterial reporter gene chloramphenicol acetyltransferase (C... | Restriction Mapping; Nucleic Acid Hybridization; Mice; Gene Expression | 1990-05-25 |
| 22 |
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Normann, Richard A. | Statistical encoding model for a primary motor cortical brain-computer interface | A number of studies of the motor system suggest that the majority of primary motor cortical neurons represent simple movement-related kinematic and dynamic quantities in their time-varying activity patterns. An example of such an encoding relationship is the cosine tuning of firing rate with respect... | Discrete Distribution; LN Model; Neural Decoding; Neuroprosthetics; Sequential Monte-Carlo Filter | 2005 |
| 23 |
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Kestle, John R. W.; Brockmeyer, Douglas Lee | Optic pathway gliomas: a review | Optic pathway gliomas represent approximately 3-5% of childhood intracranial tumors. They usually occur in children during the first decade of life and are seen in 11-30% of patients with neurofibromatosis Type 1 (NF1). Although these tumors are typically low-grade gliomas, the clinical course and n... | Optic pathway glioma; Hypothalamus glioma; Neurofibromatosis Type 1 | 2007 |
| 24 |
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Normann, Richard A.; Shoham, Shy | Encoding mechanisms for sensory neurons studied with a multielectrode array in the cat dorsal root ganglion | Recent advances in microelectrode array technology now permit a direct examination of the way populations of sensory neurons encode information about a limb's position in space. To address this issue, we recorded nerve impulses from about 100 single units simultaneously in the L6 and L7 dorsal root ... | Sensory; Encoding; Multielectrode; Dorsal Root Ganglion; Cutaneour; Muscle | 2004 |
| 25 |
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Agarwal, Nivedita | Microstructural thalamic changes in schizophrenia: a combined anatomic and diffusion weighted magnetic resonance imaging study | Objective: Several magnetic resonance imaging (MRI) and postmortem studies have supported the role of the thalamus in the pathophysiology of schizophrenia. Interestingly, a recent small diffusion weighted imaging (DWI) study showed abnormal thalamic microstructure in patients with schizophrenia. The... | | 2008-01-01 |
