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CreatorTitleDescriptionSubjectDate
1 Sung, Younghoon; Kondo, Douglas Gavin; Jeong, Eun-Kee; Renshaw, Perry FranklinReview: magnetic resonance spectroscopy studies of pediatric major depressive disorderIntroduction. This paper focuses on the application of Magnetic Resonance Spectroscopy (MRS) to the study of Major Depressive Disorder (MDD) in children and adolescents. Method. A literature search using the National Institutes of Health?s PubMed database was conducted to identify indexed peer-revie...2011
2 Dwight, Zachary LawrenceuMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web applicationuMeltSM is a flexible web-based tool for predicting DNA melting curves and denaturation profiles of PCR products. The user defines an amplicon sequence and chooses a set of thermodynamic and experimental parameters that include nearest-neighbor stacking energies, loop entropy effects, cation (mono...2011
3 Mitchell, Joyce A.50 Years of informatics research on decision support: what's nextObjectives: To reflect on the history, status, and future trends of decision support in health and biomedical informatics. To highlight the new challenges posed by the complexity and diversity of genomic and clinical domains. To examine the emerging paradigms for sup - porting cost-effective, person...2011-01-01
4 Mitchell, Joyce A.Integrating historical clinical and financial data for pharmacological researchBackground: Retrospective research requires longitudinal data, and repositories derived from electronic health records (EHR) can be sources of such data. With Health Information Technology for Economic and Clinical Health (HITECH) Act meaningful use provisions, many institutions are expected to adop...2011-01-01
5 Mitchell, Joyce A.International efforts in nanoinformatics research applied to nanomedicineBackground: Nanomedicine and nanoinformatics are novel disciplines facing substantial challenges. Since nanomedicine involves complex and massive data analysis and management, a new discipline named nanoinformatics is now emerging to provide the vision and the informatics methods and tools needed fo...2011-01-01
6 Bisson, Erica F.Management of distraction injury of the lumbosacral junction with unilateral perched facetBackground: Traumatic unilateral facet dislocation without fracture is an uncommon injury of the lumbosacral junction. We describe a case of a unilateral perched L5-S1 facet causing axial back pain and radiculopathy provoked by motion. ...Spine surgery, Facet dislocation, operative management, trauma, neurosurgery2011-01-04
7 Mitchell, Joyce A.Predicting phenotypic severity of uncertain gene variants in the RET Proto-OncogeneAlthough reported gene variants in the RET oncogene have been directly associated with multiple endocrine neoplasia type 2 and hereditary medullary thyroid carcinoma, other mutations are classified as variants of uncertain significance (VUS) until the associated clinical phenotype is made clear. Cur...2011-01-01
8 Mitchell, Joyce A.Using information prescriptions to refer patients with metabolic conditions to the Genetics Home Reference websiteObjectives: The objectives of this study were to assess the reactions of adult patients and parents of children with metabolic conditions to receipt of an ‘‘information prescription'' (IP) to visit Genetics Home Reference (GHR), a National Institutes of Health/National Library of Medicine online...2011-01-01
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