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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Warner, Homer R. | Subtotal Hysterectomy in Modern Gynecology: A Decision Analysis | Biomedical Informatics | 1997 | |
| 2 |
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Capecchi, Mario R. | Hox genes and mammalian development | We have examined the interactions of Hox genes in forming a cervical vertebrae, hindbrain, and limbs. In each case, it is apparent that individual Hox genes are performing individual functions but that more profound roles are apparent when they act in combination with others Hox genes. The observed ... | Drosophila; Gene Expression Regulation, Developmental; Homozygote | 1997 |
| 3 |
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Kestle, John R. W. | Effect of hyperventilation on regional cerebral blood flow in head-injured children | Objectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre... | Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children | 1997 |
| 4 |
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Normann, Richard A.; Jones, Kelly E. | Advanced demultiplexing system for physiological stimulation | A CMOS very large scale integration (VLSI) chip has been designed and built to implement a scheme developed for multiplexing/demultiplexing the signals required to operate an intracortical stimulating electrode array. Because the use of radio telemetry in a proposed system utilizing this chip may im... | Electrode Array; Stimulation; Telemetry; Microelectrodes; Transistors | 1997 |
| 5 |
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Gesteland, Raymond F.; Atkins, John F.; Felden, Brice; McCutcheon, John P. | Probing the structure of the Escherichia coli 10Sa RNA (tmRNA) | The conformation of the Escherichia coli 10Sa RNA (tmRNA) in solution was investigated using chemical and enzymatic probes. Single- and double-stranded domains were identified by hydrolysis of tmRNA in imidazole buffer and by lead(II)-induced cleavages. Ribonucleases T1 and S1 were used to map unpai... | Covariation; Pseudoknot; Structural Probing; 10Sa RNA; tmRNA | 1997 |
| 6 |
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Bernstein, Paul S. | Identification of lutein and zeaxanthin oxidation products in human and monkey retinas | PURPOSE: To characterize fully all the major and minor carotenoids and their metabolites in human retina and probe for the presence of the oxidative metabolites of lutein and zeaxanthin. METHODS: Carotenoids of a composite of 58 pairs of human retinas and a monkey retina were elucidated by comparing... | Mass Spectrometry; Oxidation-Reduction; Spectrophotometry, Ultraviolet | 1997 |
| 7 |
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Couldwell, William T. | Transmaxillary approach to the anterior cavernous sinus: a microanatomic study | OBJECTIVE: Several approaches to expose the anterior cavernous sinus have been used, such as frontotemporal, orbitofrontal, anterior subtemporal, and various transfacial approaches. In an effort to gain exposure to the anterior cavernous sinus without necessitating a craniotomy or wide transfacial ... | Anterior cavernous sinus; Clivus; Cranial base; Maxillary sinus | 1997 |
| 8 |
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Kriesel, John D.; Maulden, Sarah Annamarie; Spruance, Spotswood L. | Anti-interleukin-6 antibodies inhibit herpes simplex virus reactivation. | Herpes simplex viruses (HSVs) infect epithelial cells, become localized in neurons, and can reactivate in response to a variety of stimuli, including ultraviolet light and hyperthermia. The sequence of gene activation during viral replication is known, but the molecular linkage between exogenous sti... | Mice, Inbred BALB C; Tumor Necrosis Factor-alpha; Virus Activation | 1997 |
| 9 |
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Bernstein, Paul S. | Retinal tubulin binds macular carotenoids | PURPOSE: To investigate the biochemical mechanisms responsible for the specific uptake, concentration, and stabilization of the carotenoids lutein and zeaxanthin in the macula. METHODS: Soluble extracts of bovine retina mixed with radioactive carotenoids were purified by hydrophobic interaction, ion... | Chromatography, Gel; Electrophoresis; Xanthophylls | 1997 |
| 10 |
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Couldwell, William T. | Prognostic variables in surgery for skull base meningiomas | The authors have retrospectively analyzed selected surgical and pathological observations made among a group of 20 patients harboring recurrent cranial base meningiomas in an attempt to reveal which factors may be important in predicting tumor recurrence. This cohort was compared with a group of 3... | Skull base; Prognostic factor; Recurrence | 1997 |
| 11 |
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Angelucci, Alessandra | Experimentally induced retinal projections to the ferret auditory thalamus: development of clustered eye-specific patterns in a novel target | We have examined the relative role of afferents and targets in pattern formation using a novel preparation, in which retinal projections in ferrets are induced to innervate the medial geniculate nucleus (MGN). We find that retinal projections to the MGN are arranged in scattered clusters. Clusters a... | Retina; Ferrets | 1997 |
| 12 |
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Capecchi, Mario R. | Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic interactions. | Mice were generated with a targeted disruption of the homeobox-containing gene hoxb-9. Mice homozygous for this mutation show defects in the development of the first and second ribs. In most cases the first and second ribs are fused near the point at which the first and second pairs of ribs normally... | Embryonic and Fetal Development; In Situ Hybridization; Mice, Knockout | 1997-01-15 |
| 13 |
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Capecchi, Mario R. | Critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice | Angiotensin-converting enzyme (ACE) generates the vasoconstrictor angiotensin II, which plays a critical role in maintenance of blood pressure in mammals. Although significant ACE activity is found in plasma, the majority of the enzyme is bound to tissues such as the vascular endothelium. We used ta... | Blood pressure; ACE activity; Enzyme | 1997-03-06 |
| 14 |
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Varner, Michael W.; Esplin, Michael S. | Progression of pulmonary arteriovenous malformation during pregnancy: case report and review of the literature. | Arteriovenous Malformations; Pulmonary Artery; Pregnancy Complications; Pulmonary Veins; Pulmonary Artery | 1997-04 | |
| 15 |
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Varner, Michael W.; Porter T. Flint | Risk of preterm birth across generations. | OBJECTIVE: To examine the risk of preterm birth for mothers who themselves were born before term. METHODS: Data were taken from a linked data base of birth certificates composed of two cohorts: 1) a parental cohort of women born between 1947 and 1957 and 2) their offspring born between 1970 and 1992... | Preterm mothers; Pregnancy; Premature; Risk | 1997-07 |
| 16 |
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Levine, Edward M. | Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro. | The hedgehog gene family encodes secreted proteins important in many developmental patterning events in both vertebrates and invertebrates. In the Drosophila eye disk, hedgehog controls the progression of photoreceptor differentiation in the morphogenetic furrow. To investigate whether hedgehog prot... | Sonic hedgehog; Indian hedgehog; Desert hedgehog; Retina; Mitogenesis; Differentiation; Rod Photoreceptor | 1997-08-15 |
| 17 |
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Capecchi, Mario R. | Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67. | The functions of neurotransmitters in fetal development are poorly understood. Genetic observations have suggested a role for the inhibitory amino acid neurotransmitter gamma-aminobutyric acid (GABA) in the normal development of the mouse palate. Mice homozygous for mutations in the beta-3 GABAA rec... | Animals, Newborn; Crosses, Genetic | 1997-10-14 |
| 18 |
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Olson, Randall J.; Crandall, Alan S.; Mamalis, Nick | Intraoperative miotics and posterior capsular opacification following phacoemulsification with intraocular lens insertion | BACKGROUND AND OBJECTIVES: Posterior capsular opacification (PCO) is a frequent complication following phacoemulsification with intraocular lens (IOL) implantation. A series of consecutive patients receiving capsular bag-fixated, silicone IOL implants were assessed for both incidence of PCO and the ... | Intraocular Lens; Nd:YAG Laser Capsulotomy; Miochol; Miostat; Phacoemulsification; Posterior Capsular Opacification | 1997-11 |
| 19 |
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Capecchi, Mario R. | Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. | Hox genes encode transcription factors that are used to regionalize the mammalian embryo. Analysis of mice carrying targeted mutations in individual and multiple Hox genes is beginning to reveal a complex network of interactions among these closely related genes which is responsible for directing th... | Abnormalities, Multiple; Gene Targeting; Glossopharyngeal Nerve; Mice, Knockout; Morphogenesis | 1997-12-15 |
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