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CreatorTitleDescriptionSubjectDate
1 Bender, AustinThe role of ornithine, polyamines, and amino acid accumulation in the growth of melanomaA frequent adaptation in the development of melanoma is the downregulation of argininosuccinate synthetase 1 (ASS1), the rate limiting enzyme in the production of the amino acid arginine from citrulline and aspartate. It is known that ASS1 is required for cells to proliferate in the absence of argin...2024
2 Ward, Bridget E.Functionalizing a hemagglutinin epitope tag for induced mitochondrial protein degradation in saccharomyces cerevisiaeMitochondria are organelles known for their role in many critical cellular processes including the production of metabolic energy in eukaryotic cells. In order to produce this energy, mitochondria continually transport metabolites across the impermeable mitochondrial inner membrane. The transport of...2022
3 Kearns, Ireland RoseEffects of trem-1 expression on acute phase seizures in a mouse model of viral-induced epilepsyAround 70 million people worldwide suffer from epilepsy, a neurological disorder that causes unprovoked and persistent seizures. A dominant cause of acquired epilepsies are from injuries to the central nervous system (CNS), such as viral infection of the CNS that results in brain inflammation (encep...2022
4 Enquist, AnnekeDiscovery of platinum (II) and azulene derivative cocrystals with fluorinated cyanoaromaticsPentacyano-trifluoromethyl benzene was synthesized using a novel technique. Before isolation, it was noted that plate like crystals had formed leading to study regarding the ability of acetic acid to co-crystallize with pentacyanotrifluoromethyl benzene. The crystal structure of acetic acid with pen...2024
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