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Creator | Title | Description | Subject | Date |
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Dailey, Andrew T. | Agreement between orthopedic surgeons and neurosurgeons regarding a new algorithm for the treatment of thoracolumbar injuries: a multicenter reliability study | Introduction: Considerable variability exists in the management of thoracolumbar (TL) spine injuries. Although there are many influences, one significant factor may be the treating surgeon's specialty and training (ie, orthopedic surgery vs. neurosurgery). Our objective was to assess the agreement ... | Thoracolumbar injuries; Rating; Classification; TLISS; Neurosurgery; Interspeciality reliability | 2006 |
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Dailey, Andrew T.; Brodke, Darrel S.; Bachus, Kent N. | Anterior cervical fixation: analysis of load-sharing and stability with use of static and dynamic plates | Background: Anterior plates provide stability following decompression and fusion of the cervical spine. Various plate designs have emerged, and they include static plates with fixed-angle screws, rotationally dynamic plates that allow the screws to toggle in the plate, and translationally dynamic pl... | Anterior cervical fixation; Load-sharing; Stability; Static plates; Dynamic plates | 2006 |
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Hunt, Steven C.; Adams, Ted; Hopkins, Paul N.; Hunt, Steven C. | ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes | Adipose triglyceride lipase (ATGL) was recently described to predominantly perform the initial step in triglyceride hydrolysis and therefore seems to play a pivotal role in the lipolytic catabolism of stored fat in adipose tissue. In the first study investigating genetic variations within the ATGL g... | Diabete, Type 2; ATGL; Fat; Triglycerides | 2006 |
| 4 |
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Couldwell, William T.; Orlandi, Richard R. | Carotid artery-sparing repair of a cavernous carotid artery pseudoaneurysm | Carotid artery (CA) injury after transsphenoidal and endoscopic sinus surgery is a well-recognized but fortunately rare complication.1 It is associated with significant morbidity and mortality rates5 and is more common in cases of repeated surgery, cavernous sinus invasion, prior radiotherapy, and ... | Carotid artery; Sinus; Pseudoaneurysm; Endoscopic surgery | 2006 |
| 5 |
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Schmidt, Meic H. | Cervical spine deformity associated with resection of spinal cord tumors | Postoperative sagittal-plane cervical spine deformities are a concern when laminectomy is performed for tumor resection in the spinal cord. These deformities appear to occur more commonly after resection of intramedullary spinal cord lesions, compared with laminectomy for stenosis caused by degener... | Kyphosis; Cervical deformity; Intramedullary tumor; Laminectomy; Children | 2006 |
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Baehr, Wolfgang | Cloning and molecular characterization of cGMP-gated ion channels from rod and cone photoreceptors of striped bass ( M. saxatilis ) retina | Vertebrate photoreceptors respond to light with changes in membrane conductance that reflect the activity of cyclic-nucleotide gated channels (CNG channels). The functional features of these channels differ in rods and cones; to understand the basis of these differences we cloned CNG channels from t... | Amino Acid Sequence; Computational Biology; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
| 7 |
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Couldwell, William T. | Combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumors | COMPLEX TUMORS OF the glomus jugulare present a surgical challenge because of their difficult location, extreme vascularity, and involvement with multiple cranial nerves. Modern microneurosurgical and cranial base techniques have enabled safe total removal of these complicated tumors. We describe a ... | Cranial base approach; Surgical approach; Glomus jugulare tumor; Jugular foramen exposure; Microsurgical anatomy | 2006 |
| 8 |
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Couldwell, William T. | Comment on Nugent, G. R.: Targeting the ventral lateral nucleus of the thalamus: a stereotactic vignette | Dr. Nugent provides a fascinating personal account of his early experience with stereotactic surgery for movement disorders. I was especially pleased to read the positive comments regarding the personal interactions with and innovations of Irving Cooper, a neurosurgeon who was derided by his peers b... | Stereotactic surgery; Stereotaxis | 2006 |
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Couldwell, William T. | Comment on Wong, H. T., et al.: Comparative impact of video consultation on emergency neurosurgical referrals | The Author's explored the facility and accuracy of telephone, teleradiology, or video consultation between a large general hospital and their tertiary neurosurgical center. Although there was increased diagnostic accuracy with video consultation or teleradiology, they note that consultation via vid... | Teleradiology; Video consultation; Neurosurgical referrals | 2006 |
| 10 |
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Couldwell, William T.; Jensen, Randy L.; Jensen, Elizabeth M. | Development of contrast enhancement after long-term observation of a dysembryoplastic neuroepithelial tumor | Dysembryoplastic neuroepithelial tumors (DNET) are usually benign lesions that arise in cortical regions and are discovered after new onset of seizure. These lesions have many different imaging characteristics. We report a patient with a presumed low-grade medial temporal lobe lesion that was follow... | Brain tumor; Dysembryoplastic neuroepithelial tumors; DNET; Imaging; Seizures | 2006 |
| 11 |
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Dailey, Andrew T. | Diagnosis and treatment of craniocervical dislocation in a series of 17 consecutive survivors during an 8-year period | Object. Craniocervical dissociation (CCD) is a highly unstable and usually fatal injury resulting from osseoligamentous disruption between the occiput and C-2. The purpose of this study was to elucidate systematic factors associated with delays in diagnosing and treating this life-threatening condit... | Spinal cord injury; Craniocervical dislocation; Atlantooccipital joint; Atlantoaxial joint; Tetraplegia; CCJ; CCD | 2006 |
| 12 |
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Gesteland, Raymond F.; Atkins, John F.; Baranov, Pavel V. | Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons | ABSTRACT: Background: While all codons that specify amino acids are universally recognized by tRNA molecules, codons signaling termination of translation are recognized by proteins known as class-I release factors (RF). In most eukaryotes and archaea a single RF accomplishes termination at all three... | Class-I release factors; RF1; RF2; Bacterial genomes | 2006 |
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Gesteland, Raymond F.; Atkins, John F. | Evolutionary specialization of recoding: frameshifting in the expression of S. cerevisiae antizyme mRNA is via an atypical antizyme shift site but is still +1 | An autoregulatory translational shift to the +1 frame is required for the expression of ornithine decarboxylase antizyme from fungi to mammals. In most eukaryotes, including all vertebrates and a majority of the studied fungi/yeast, the site on antizyme mRNA where the shift occurs is UCC-UGA. The me... | Antizyme; ODC; Polyamines; Frameshifting | 2006 |
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Couldwell, William T.; Schmidt, Richard H.; Salzman, Karen L.; Chin, Steven S. | Glioblastoma multiforme of the pineal region | Glioblastoma multiforme (GBMs) tumors are exceedingly rare tumors in the pineal region. We present three cases in which patients presented with a pineal/posterior third ventricular region mass and review all the previously reported cases in the literature. Pineal region GBM seems to be a very aggre... | Glioblastoma multiforme; Hydrocephalus; Leptomeningeal dissemination; Malignant glioma; Perinaud's syndrome; Pineal region; Spinal metastases | 2006 |
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Zhang, Kang | Heterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalities | PURPOSE: The PITX3 gene, which codes for a homeobox bicoidlike transcription factor is responsible for dominant cataract and anterior segment mesenchymal dysgenesis in humans. In the current study, a family with autosomal dominant posterior polar cataract (PPC) and a PITX3 mutation that cosegregates... | Chromosomes, Human, Pair 10; Homozygote; Lod Score | 2006 |
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Nebeker, Jonathan R.; Samore, Matthew H | Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the research on adverse drug events and reports (RADAR) project | OBJECTIVES: We undertook the review of all available cases of hypersensitivity reactions after placement of a drug-eluting stent (DES) and classified potential causes. BACKGROUND: Six months after the approval of the first DES, the Food and Drug Administration (FDA) reported 50 hypersensitivity reac... | Drug Hypersensitivity; Coronary Vessels | 2006 |
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Gardner, Reed M. | Impact of CPOE on Mortality Rates - Contradictory Findings, Important Messages | Biomedical Informatics | | 2006 |
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Couldwell, William T. | Increasing exposure of the petrous internal carotid artery for revascularization using the transzygomatic extended middle fossa approach: a cadaveric morphometric study | When internal carotid artery (ICA) sacrifice is planned in the management of difficult tumors or aneurysms at the cranial base, the petrous ICA may be a useful site for anastomosis for interpositional vascular bypass. However, exposure of the artery and performing an anastomosis in this region may... | Revascularization; Internal carotid artery; Cranial base tumors; Giant aneurysms; Interpositional bypass; Surgical approach; Middle fossa | 2006 |
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Couldwell, William T. | Inflammatory pseudotumor of the cavernous sinus and skull base | Inflammatory pseudotumor is a non-neoplastic process of unknown etiology characterized by a proliferation of connective tissue with an inflammatory infiltrate. Intracranial inflammatory pseudotumors classically involve the cavernous sinus but can also occur in the supratentorial or infratentorial c... | Intracranial neoplasm; Pseudotumor; Skull base | 2006 |
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Warner, Judith E. A. | Intermittent reversal of Complete Ptosis-EganWarner | CASE REPORT: Ptosis secondary to dense oculomotor pareses generally improves over several months, but intermittent elevation of the eyelid has not been reported. The Author's describe two patients who demonstrated intermittent involuntary monocular eyelid elevation in an eye with complete ptosis cau... | Eyelids; Ophthalmoplegia; Intraoperative Complications | 2006 |
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Kestle, John R. W. | Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literature | Object. Late rapid deterioration after endoscopic third ventriculostomy (ETV) is a rare complication. The authors previously reported three deaths from three centers. Three other deaths and a patient who experienced rapid deterioration have also been reported. Following the death at the University ... | Endoscopic third ventriculostomy; ETV; Pediatric neurosurgery; Adverse outcome | 2006 |
| 22 |
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Kestle, John R. W. | Management of shunt infections: a multicenter pilot study | Object. Approximately 10% of cerebrospinal fluid (CSF) shunt operations are associated with infection and require removal or externalization of the shunt, in-hospital treatment with antibiotic agents, and insertion of a new shunt. In a previous survey, the authors identified substantial variation i... | Shunt infections; Ventriculoperitoneal shunt; Treatment evaluation | 2006 |
| 23 |
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Couldwell, William T.; Viskochil, David H.; Fults, Daniel Webster | Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications | NEUROFIBROMATOSIS 1 (NF1) IS A common autosomal dominant disease characterized by complex and multicellular neurofibroma tumors. Significant advances have been made in the research of the cellular, genetic, and molecular biology of NF1. The NF1 gene was identified by positional cloning. The function... | Loss of heterozygosity; Malignant peripheral nerve sheath tumor; Plexiform Neurofibroma; Spinal neurofibroma | 2006 |
| 24 |
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Kestle, John R. W.; Walker, Marion L. | Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a child | Extradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de... | | 2006 |
| 25 |
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Mamalis, Nick; Nilson, Christian D. | Outbreak of toxic anterior segment syndrome following cataract surgery associated with impurities in autoclave steam moisture. | BACKGROUND: Toxic anterior segment syndrome (TASS), a complication of cataract surgery, is a sterile inflammation of the anterior chamber of the eye. An outbreak of TASS was recognized at an outpatient surgical center and its affiliated hospital in December 2002. METHODS: Medical records of patients... | Toxic anterior segment syndrome; cataract surgery; autoclave steam moisture | 2006 |
