626 - 650 of 1,952
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CreatorTitleDescriptionSubjectDate
626 Jorgensen, ErikFunction and misfunction of the two promoters of the Drosophila Antennapedia geneIn the Antennapedia (Antp) gene of Drosophila melanogaster, structurally distinct RNAs arise from different transcription initiation sites. When the two sites are separated by a chromosome inversion, transcripts are produced from each fragment of the split Antp locus, and these RNAs initiate at the ...RNA; Antp; Hybridization1987
627 Carrier, David R.Functional tradeoffs in specialization for fighting versus runningBoth locomotion and fighting are critical to survival and reproductive fitness in many vertebrate species. Yet, characters that make an individual good at fighting may, in many cases, limit locomotor performance and vice versa. Here I describe tests of three functional tradeoffs in the limb muscles ...Greyhounds; Pit Bulls; Australopithecus; Homo; Fighting; Running; Male-male aggression; Limb muscles; Functional tradeoff2002
628 Capecchi, Mario R.Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein.The 180-amino acid core of the TATA-binding protein (TBPcore) is conserved from Archae bacteria to man. Vertebrate TBPs contain, in addition, a large and highly conserved N-terminal region that is not found in other phyla. We have generated a line of mice in which the tbp allele is replaced with a v...Mice, Knockout; Cells, Cultured; Fibroblasts; Embryo2003-02-21
629 Voth, Gregory AlanFurther developments in the local-orbital density-functional-theory tight-binding methodQuantum-mechanical methods have become increasingly reliable as a complementary tool to experimental research. A variety of methods exist ranging in complexity from semiempirical methods to density-functional-theory (DFT) methods [using either the local-density approximation (LDA) or the generalize...Sankey-Niklewaki method; Fireball method; Pseudopotential; Exchange-correlation interactions; Gallium nitride; H20 dimer; Copper; gas-phase HMX2001-10
630 Ailion, David CharlesGallium and thallium NMR study of phase transitions and incomemensurability in the layered semiconductor TlGaSe2We report on the first NMR study of phase transitions and incommensurability in the layered semiconductor TlGaSe2. 69,71Ga and 205Tl NMR data from a powder sample show phase transitions at 118, 108 and around 69 K. The 69Ga and 71Ga spin-lattice relaxation times T1 are short and nearly temperature i...NMR; Atomic motion; Phase transitions; Spin-lattice; Relaxation-time2004
631 Kieda, David B.; Binks, Joshua ThomasGamma-ray emission by the BL Lac Markarian 501Optical astronomy is the study of the heavens as they emit light, or the visible portion of the electromagnetic spectrum. Gamma-ray astronomy is the study of astrophysical sources that emit the most energetic form of electromagnetic radiation (ie: gamma-rays). High Energy gamma-rays are much too f...Markarian 501; Gamma-ray emission; Trapeze Interactive Poster2010-03-15
632 Gondolo, PaoloGamma-ray summary reportThis paper reviews the field of gamma-ray astronomy and describes future experiments and prospects for advances in fundamental physics and high-energy astrophysics through gamma-ray measurements. We concentrate on recent progress in the understanding of active galaxies, and the use of these sources ...EGRET; GLAST; VERITAS2001
633 Mishchenko, EugeneGapless surfaces in anisotropic superfluidsWe demonstrate when p-wave pairing occurs between species whose free Fermi surfaces are mismatched the gap generally vanishes over a two-dimensional surface. We present detailed calculations of condensation energy, superfluid density (Meissner mass) and specific heat for such states. We also consi...Anisotropic superfluids; Meissner mass2006-11
634 Ehleringer, James R.Gas exchange, δ13C, and heterotrophy for Castilleja linariifolia and Orthocarpus tolmiei, facultative root hemiparasites on Artemisia tridentataGas exchange and carbon isotope ratios were measured on 2 facultative hemiparasites, Castilleja linarifolia Benth. (Indian paintbrush; Scrophulariaceae) and Orthocarpus tolmiei I-I. & A. (Tolmie owl clover; Scrophulariaceae), and their Artemisia tridentata L. (big sagebrush; Asteraceae) hosts. Photo...Heterotrophy; Hemiparasite; Carbon isotope ratios; Shrub ecology; Castilleja linarifolia; Orthocarpus tolmiei; Artemisia tridentata1996
635 Saam, Brian; Pugmire, Ronald J.Gas-phase spin relaxation of 129XeWe have completed an extensive study of 129Xe longitudinal spin relaxation in the gas phase, involving both intrinsic and extrinsic mechanisms. The dominant intrinsic relaxation is mediated by the formation of persistent Xe2 van der Waals dimers. The dependence of this relaxation on applied magnetic...129Xe; Gas-phase spin relaxation2008-10
636 Wu, Yong-ShiGauge invariance of fractionally charged quasiparticles and hidden topological Zn symmetryUsing the braid-group formalism we study the consequences of gauge invariance for fractionally charged anyonic quasiparticles in a two-dimensional multiply connected system. It is shown that gauge invariance requires multicomponent wave functions, and leads to the emergence of a hidden topological...Gauge invariance; Topological Zn symmetry; Braid-group representation1991-02
637 Jorgensen, Erik; Carroll, DanaGene activation using FLP recombinase in C. elegansThe FLP enzyme catalyzes recombination between specific target sequences in DNA. Here we use FLP to temporally and spatially control gene expression in the nematode C. elegans. Transcription is blocked by the presence of an "off cassette" between the promoter and the coding region of the desired pro...2008
638 Capecchi, Mario R.Gene targeting. How efficient can you get?With targeting in Leishmania and Trypanosoma, there are now greater incentives to develop the technology in organisms of intermediate complexity such as Caenorhabditis elegans and Drosophila. The ratio of homologous to nonhomologus recombination in these organisms might prove to be greater than in m...Animals; DNA Mutational Analysis; Recombination, Genetic1990-11-08
639 Capecchi, Mario R.Gene targeting: an historical perspectiveOur entry into what was going to become the field of gene targeting began in 1977. I was experimenting with the use of extremely small glass needles to inject DNA directly into the nuclei of living cells. The needles were controlled by hydraulically driven micro-manipulators and were directed into n...Gene targeting -- History; Homologous recombination1998
640 Capecchi, Mario R.Gene targeting: tapping the cellular telephone.Gene targeting means that we now have the potential to generate mice of virtually any desired genotype. In the first instance, standards recombinant DNA technology is used to alter a cloned DNA sequence of a chosen locus; the modified potent stem cell derived from a mouse embryo, and homologous reco...Animals; Blotting, Southern; Bone and Bones; Gene Targeting; Genotype; Immunochemistry; In Situ Hybridization; Mice1990-03-08
641 Adler, Frederick R.General test for interaction modificationHow can measurements of population dynamics be used to deduce the mechanisms of interaction in an assemblage of species? We present a technique to use such measurements to distinguish among assemblages of species with no direct interactions, sets of species influenced predominantly by pairwise inter...Species; Population; Dynamics1994
642 Wu, Yong-ShiGeneral theorem relating the bulk topological number to edge states in two-dimensional insulatorsWe prove a general theorem on the relation between the bulk topological quantum number and the edge states in two-dimensional insulators. It is shown that whenever there is a topological order in bulk, characterized by a nonvanishing Chern number, even if it is defined for a nonconserved quantity s...Edge states; Bulk topology; Chern number2006-07
643 Wu, Yong-ShiGeneral theory for quantum statistics in two dimensionsBecause of complicated topology of the configuration space for indistinguishable particles in two dimensions, Feynman's path-integral formulation allows exotic statistics. All possible quantum statistics in two-space are characterized by an angle parameter 9 which interpolates between bosons and fe...Homotopy classes1984-06
644 Capecchi, Mario R.Generating mice with targeted mutations.Mutational analysis is one of the most informative approaches available for the study of complex biological processes. It has been particularly successful in the analysis of the biology of bacteria, yeast, the nematode worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster. Extension ...Animals; Recombination, Genetic; Stem Cells2001-10-01
645 Mishchenko, EugeneGeneration of spin current by Coulomb dragCoulomb drag between two quantum wires is exponentially sensitive to the mismatch of their electronic densities. The application of a magnetic field can compensate this mismatch for electrons of opposite spin directions in different wires. The resulting enhanced momentum transfer leads to the conv...Spin current; Coulomb drag; Quantum wires2006-12
646 Beckerle, Mary C.; Hoffman, Laura M.; Yoshigi, MasaakiGenetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodelingFocal adhesions are specialized regions of the cell surface where integrin receptors and associated proteins link the extracellular matrix to the actin cytoskeleton. To define the cellular role of the focal adhesion protein zyxin, we characterized the phenotype of fibroblasts in which the zyxin gene...Zyxin; Actin; Mena/VASP2006
647 Clayton, Dale H.; Rogers, Alan R.Genetic analysis of lice supports direct contact between modern and archaic humansParasites can be used as unique markers to investigate host evolutionary history, independent of host data. Here we show that modern human head lice, Pediculus humanus, are composed of two ancient lineages, whose origin predates modern Homo sapiens by an order of magnitude (ca. 1.18 million years).Pediculus humanus; Head lice; Molecular phylogeny; Phthirus2004
648 Adler, Frederick R.Genetic and phylogenetic consequences of island biogeographyIsland biogeography theory predicts that the number of species on an island should increase with island size and decrease with island distance to the mainland. These predictions are generally well supported in comparative and experimental studies. These ecological, equilibrium predictions arise as a...Extinction; Genetic divergence; Island isolation; Migration; Speciation2000
649 Shapiro, Michael D.Genetic architecture of parallel armor plate reduction in threespine sticklebacksHow many genetic changes control the evolution of new traits in natural populations? Are the same genetic changes seen in cases of parallel evolution? Despite long-standing interest in these questions, they have been difficult to address, particularly in vertebrates. We have analyzed the genetic bas...Genetic changes; Plate number; Genetic mapping2004
650 Shapiro, Michael D.Genetic architecture of skeletal convergence and sex determination in ninespine sticklebacksThe history of life offers plentiful examples of convergent evolution, the independent derivation of similar phenotypes in distinct lineages [1]. Convergent phenotypes among closely related lineages (frequently termed "parallel" evolution) are often assumed to result from changes in similar genes or...Convergent evolution; Skeletal convergence; Pungitius pungitius; Gasterosteus aculeatus; Comparative genetics2009-07
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