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CreatorTitleDescriptionSubjectDate
1 Olson, Randall J.; Coldwell, Karin D.; Compton, Bruce J.; Giddings, John C.Sedimentation field-flow fractionation: a method for studying particulates in cataractous lensIt is shown that the technique of sedimentation field-flow fractionation (sedimentation [sed] FFF) can be used to determine the particle content and particle size distribution of normal and cataractous lenses. A 31-year-old normal human lens, for example, showed a particle content of 1.5% by weight ...Fractionation; Cataractous Lens; Particulates1984
2 Baehr, WolfgangTissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding proteinInterphotoreceptor retinoid-binding protein (IRBP) is an extracellular protein that has been suggested to participate in the visual process as a carrier for visual retinoids. A chimeric gene composed of the human IRBP promoter fused to the bacterial reporter gene chloramphenicol acetyltransferase (C...Restriction Mapping; Nucleic Acid Hybridization; Mice; Gene Expression1990-05-25
3 Bastiani, MichaelLoss of axons in the cat optic nerve following fetal unilateral enucleation: an electron microscopic analysisBetween the 48th day of gestation (E-48) and maturity, the number of axons in the cat optic nerve is reduced by approximately 50%. On the basis of an electron microscopic assay, the axon population of the E-48 nerve was estimated to be 328,000. In contrast, estimates from two normal adults were 159,...Ganglion cell death; Retinofugal projection; Retinal ganglion cell axons1983
4 Allen, Edgar S.Sensory information processing and symbolic computation (1 Jan. 1975 - 30 June 1975)This research uses digital computation to investigate processes, both linear and nonlinear, for the filtering. restoration, enhancement, bandwidth reduction, distortion immunization and analysis of both visual and auditory information.Sensory information processing; Symbolic computation; Auditory information; Visual information1973
5 Jorgensen, ErikNeural plasticityNeural plasticity refers to functional changes in the nervous system and therefore encompasses a range of phenomena from changes at synapses observed on a microscopic scale to changes in behavior observed in the whole animal. These diverse phenomena are related since changes in synapses are believ...Synapses; Nervous System; Development1997
6 Jorgensen, ErikCaenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic developmentThe neurotransmitter GABA has been proposed to play a role during nervous system development. We show that the Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase (GAD), the GABA biosynthetic enzyme. unc-25 is expressed specifically in GABAergic neurons. Null mutations in unc-25...1999
7 Olivera, Baldomero M.Identification and characterization of a Ca2+-sensitive nonspecific cation channel underlying prolonged repetitive firing in Aplysia neuronsThe afterdischarge of Aplysia bag cell neurons has served as a model system for the study of phosphorylation-mediated changes in neuronal excitability. The nature of the depolarization generating the afterdischarge, however, has remained unclear. We now have found that venom from Conus textile trig...Ca21-activated nonspecific cation channel; Slow inward current; Ion channel modulation; Afterdischarge; Bursting; Aplysia bag cell neurons; Conus textile; Neurotoxins1996
8 Bastiani, MichaelPathfinding by neuronal growth cones in grasshopper embryos: II. Selective fasciculation onto specific axonal pathwaysIn the previous paper (Raper, J. A., M. Bastiani, and C. S. Goodman (1983) J. Neurosci. 3: 20-30) we showed that the growth cones of two sibling neurons, the G and C cells, follow the same route in the developing grasshopper neuropil until they reach a stereotypic choice point. Here their growth con...Neurons; Axons; Neuropil1983
9 Yamaguchi, AyakoCoding rate and duration of vocalizations of the frog , Xenopus laevisVocalizations involve complex rhythmic motor patterns, but the underlying temporal coding mechanisms in the nervous system are poorly understood. Using a recently developed whole-brain preparation from which "fictive" vocalizations are readily elicited in vitro, we investigated the cellular basis of...2012-08-29
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