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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
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Bastiani, Michael | Developmental expression and biochemical analysis of Conulin, a protein secreted from a subset of neuronal growth cones | In this report, we analyze the developmental pattern of expression of a new grasshopper protein, Conulin, using the monoclonal antibody 7D2 on whole-mount embryos and dissociated neurons. We also have examined its biochemical properties by immunoblot analysis. Conulin is a protein expressed by a su... | Conulin; Growth cone-specific protein; Secreted protein; Selective tasciculation; CNS-specific protein; Pathfinding | 1996 |
| 2 |
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Capecchi, Mario R. | Lessons from angiotensin-converting enzyme-deficient mice | Since the first description of renin by Tigerstedt and Bergman [1] in 1898, many papers have described the biochemistry and physiological roles of the reninangiotensin system [2]. A critical component of this system is angiotensin-converting enzyme (ACE), a peptidase which cleaves the inactive pep... | 1996 | |
| 3 |
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Capecchi, Mario R. | Lessons from angiotensin-converting enzyme-deficient mice. | Mice which lack ACE have low systolic blood pressure, reduced male fertility and a renal abnormality characterized by medullary hypoplasia and the inability to concentrate urine. The diverse phenotypes caused by inactivation of a single gene emphasize the many functional roles of ACE and the renin-q... | Blood Pressure; Cell Line;Fertility; Kidney; Testis | 1991-11-01 |
| 4 |
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Capecchi, Mario R. | Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions. | The Hox genes encode transcription factors which mediate the formation of the mammalian body plan along the anteroposterior and appendicular axes. Paralogous Hox genes within the separate linkage groups are closely related with respect to DNA sequence and expression, suggesting that they could have ... | Animals; Atlas; Homozygote; Mice; Models, Genetic | 1994-07-28 |
| 5 |
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Olivera, Baldomero M. | Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology | The predatory cone snails (Conus) are among the most successful living marine animals (~500 living species). Each Conus species is a specialist in neuropharmacology, and uses venom to capture prey, to escape from and defend against predators and possibly to deter competitors. An individual cone... | Conotoxins | 1997 |
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