|
|
Creator | Title | Description | Subject | Date |
1 |
|
Clayton, Dale H.; Rogers, Alan R. | Genetic analysis of lice supports direct contact between modern and archaic humans | Parasites can be used as unique markers to investigate host evolutionary history, independent of host data. Here we show that modern human head lice, Pediculus humanus, are composed of two ancient lineages, whose origin predates modern Homo sapiens by an order of magnitude (ca. 1.18 million years). | Pediculus humanus; Head lice; Molecular phylogeny; Phthirus | 2004 |
2 |
|
Adler, Frederick R.; Carrier, David R. | Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water Dogs | Size sexual dimorphism occurs in almost all mammals. In Portuguese Water Dogs, much of the difference in skeletal size between females and males is due to the interaction between a Quantitative Trait Locus (QTL) on the X-chromosome and a QTL linked to Insulin-like Growth Factor 1 (IGF-1) on the CFA... | Phenotypes; QTL; Selection | 2005 |
3 |
|
Adler, Frederick R. | Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression | Insulin resistance, characterized by a reduced cellular response to insulin, is a major factor in type 2 diabetes pathogenesis, with a complex etiology consisting of a combination of environmental and genetic factors. Oxidative stress, which develops through an accumulation of toxic reactive oxygen ... | | 2014-01-01 |
4 |
|
Seger, Jon | Conditional relatedness, recombination, and the chromosome numbers of insects | If two polymorphic loci are out of phase equilibrium, a homozygote at one of these loci is more highly related to its kin, at the other locus, than is an equivalent heterozygote. As a result, selection can favor (1) phenotypic responses to relative heterozygosity, and (2) increased recombination bet... | Coefficients of relatedness; Conditional relatedness | 1983 |
5 |
|
Sekercioglu, Cagan | Promoting community-based bird monitoring in the tropics: conservation, research, environmental education, capacity-building, and local incomes | Long-term, locally-based biodiversity monitoring programs are essential for understanding and mitigating the effects of global change on tropical biodiversity while providing capacity-building, environmental education, and public outreach. However, these programs are lacking in most tropical countri... | | 2011-01-01 |
6 |
|
Bastiani, Michael | Loss of axons in the cat optic nerve following fetal unilateral enucleation: an electron microscopic analysis | Between the 48th day of gestation (E-48) and maturity, the number of axons in the cat optic nerve is reduced by approximately 50%. On the basis of an electron microscopic assay, the axon population of the E-48 nerve was estimated to be 328,000. In contrast, estimates from two normal adults were 159,... | Ganglion cell death; Retinofugal projection; Retinal ganglion cell axons | 1983 |
7 |
|
Hultine, Kevin; Bush, Sarah Elizabeth; Ehleringer, James R. | Effect of gender on sap-flux-scaled transpiration in a dominant riparian tree species: Box elder (Acer negundo) | Acer negundo is a dioecious riparian tree species with a spatial segregation of the sexes along soil moisture gradients. Females are typically more common in wet sites along streams (typically F/M = 1.6), whereas males are more common in drier sites away from streams (typically F/M = 0.6). Spatial s... | Density; Ecosystem; Segregation | 2007 |
8 |
|
Bernstein, Paul S.; Gellermann, Werner | Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions. | We have developed a CCD-camera-based nonmydriatic instrument that detects fluorescence from retinal lipofuscin chromophores ("autofluorescence") as a means to indirectly quantify and spatially image the distribution of macular pigment (MP). The lipofuscin fluorescence intensity is reduced at all ret... | Cytology; Sensitivity and Specificity | 2006-10 |
9 |
|
Adler, Frederick R. | How virulent should a parasite be to its vector? | Vector-borne parasites are commonly predicted to be less virulent to the vector than to the definitive host as the parasite gains little by harming its main route of transmission. Here we assess the empirical evidence from systems in which insects are vectors for vertebrate, plant, and invertebrate ... | Parasite virulence; Hosts; Vector-borne parasite | 2003 |
10 |
|
Adler, Frederick R. | Super- and coinfection: filling the range | How many different strains of a disease can coexist in a single population of hosts? What effect do different mechanisms of coexistence have on the properties of diseases? The principle of competitive exclusion (Armstrong and McGehee 1980; Levin 1970) states that no more species can coexist in a sys... | Superinfection; Virulence; Coexistence | 2002 |
11 |
|
Capecchi, Mario R. | Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase. | We have examined the effect of cell cycle position on homologous recombination between plasmid molecules coinjected into synchronized rat fibroblasts. Recombination activity was found to be low in G1 and to rise 10- to 15-fold, peaking in early to mid-S phase. | Cell Line; Kinetics; Plasmids | 1986-06 |
12 |
|
Sekercioglu, Cagan | The need to quantify ecosystem services provided by birds | What are birds worth-what is their actual dollar value to human society? To most of us in the ornithological community, birds are invaluable. But in these times we need more specific rationales to convince policy makers and business leaders to include bird conservation in land-use and development de... | | 2011-01-01 |
13 |
|
Davidson, Diane W. | Nonnative brome grasses in the new national monument | Included within the boundaries of the Grand-Staircase Escalante National Monument are a number of noxious weeds for which the BLM mandates control. In addition to listed weeds are nonnative brome grasses [Bromus tectorum and Bromus rubens), which can potentially convert native ecosystems to biologic... | Noxious weeds, Cheatgrass, | 1998 |
14 |
|
Shapiro, Michael D. | Genetic architecture of parallel armor plate reduction in threespine sticklebacks | How many genetic changes control the evolution of new traits in natural populations? Are the same genetic changes seen in cases of parallel evolution? Despite long-standing interest in these questions, they have been difficult to address, particularly in vertebrates. We have analyzed the genetic bas... | Genetic changes; Plate number; Genetic mapping | 2004 |
15 |
|
Potts, Wayne K. | Surprisingly uneven distribution of the T cell receptor Vβ repertoire in wild mice | Heterodimeric TCRa/Bs are made up of combinations of V D, J, and C elements. The majority of laboratory inbred mouse strains are of the VBh haplotype and have at least 20 VB genes from which to construct TCRs (1, 2); however, a number of strains have been reported to have deletions of large portion... | | 1990 |
16 |
|
Adler, Frederick R. | Mathematical model of a three-stage innate immune response to a pneumococcal lung infection | Pneumococcal pneumonia is a leading cause of death and a major source of human morbidity. The initial immune response plays a central role in determining the course and outcome of pneumococcal disease. We combine bacterial titer measurements from mice infected with Streptococcus pneumoniae with mat... | | 2011 |
17 |
|
Potts, Wayne K.; Granger, Donald Lee | Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice | To evaluate the role of major histocompatibility complex (MHC) genes in the resistance to Cryptococcus neoformans, we conducted infection experiments in MHC-congenic strains of mice. Significant MHC-dependent susceptibility differences were found among homozygotes and heterozygotes. This study is th... | MHC-congenic; Host resistance; Infection | 2003 |
18 |
|
Clayton, Dale H. | Darwins finches combat introduced nest parasites with fumigated cotton | Introduced parasites are a threat to biodiversity when naïve hosts lack effective defenses against such parasites [1]. Several parasites have recently colonized the Galápagos Islands, threatening native bird populations [2]. For example, the introduced parasitic nest fly Philornis downsi (Diptera:... | | 2014-01-01 |
19 |
|
Sekercioglu, Cagan | Causes and consequences of bird extinctions | Increased human domination of the planet has caused the declines and extinctions of countless species. Each species has not only intrinsic value, but ecological functions of organisms are also essential for the integrity of ecosystems that allow people to benefit from essential free ecosystem servic... | | 2003-01-01 |
20 |
|
Lawton, Kristy J. | Motor neurons tune premotor activity in a vertebrate central pattern generator | Central patterns generators (CPGs) are neural circuits that drive rhythmic motor output without sensory feedback. Vertebrate CPGs are generally believed to operate in a top-down manner in which premotor interneurons activate motor neurons that in turn drive muscles. In contrast, the frog (Xenopus la... | CPG; feed back; synchrony; vocal; vocalization; Xenopus | 2017 |
21 |
|
Ehleringer, James R.; Belnap, Jayne | Sensitivity of the Colorado plateau to change: climate, ecosystems, and society | The Colorado Plateau is located in the interior, dry end of two moisture trajectories coming from opposite directions, which have made this region a target for unusual climate fluctuations. A multidecadal drought event some 850 years ago may have eliminated maize cultivation by the first human settl... | Colorado Plateau; Biological crust; Climate change; Megadrought; Ranching; Dry crop productivity; Extractive industries; Pueblo Indians; Fremont culture | 2008 |
22 |
|
Potts, Wayne K. | Major histocompatibility complex heterozygote superiority during coinfection | Genes of the major histocompatibility complex (MHC) play a critical role in immune recognition, and many alleles confer susceptibility to infectious and autoimmune diseases. How these deleterious alleles persist in populations is controversial. | Pathogen; MHC; Homozygotes | 2003 |
23 |
|
Adler, Frederick R.; Liou, Theodore G.; Cahill, Barbara C. | Selection of patients with cystic fibrosis for lung transplantation | Lung transplantation is the most aggressive therapy available for end-stage lung disease from cystic fibrosis (CF). A new predictive survival model of CF uses demographic, FEV1, nutritional, microbiologic, and acute exacerbation data to produce precise estimates of 5-year survival. | Predicted survival; Living donor; Mechanical ventilation | 2002 |
24 |
|
Capecchi, Mario R. | How close are we to implementing gene targeting in animals other than the mouse? | Describes several significant contributions that bring us much closer to extending ‘‘gene targeting'' to mammalian species other than the mouse. Gene targeting now provides the means for creating new strains of mice with mutations in virtually any gene. First, the desired mutation is introduced ... | Cattle; Mutagenesis; Mice; Humans; Ethics, Medical | 2000-02-01 |
25 |
|
Beckerle, Mary C.; Davis, Darrell R.; Winge, Dennis R. | Mutational analysis of the metal sites in an LIM domain | Site-directed mutagenesis was carried out map the residues that form the two Zn(I1) sites within a LIM domain. The C-terminal LIM domain derived from the cysteine-rich protein was utilized for this analysis and is referred to as LIMB. | LIM domains; Metal-binding | 1994 |