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CreatorTitleDescriptionSubjectDate
26 Davidson, Diane W.Nonnative brome grasses in the new national monumentIncluded within the boundaries of the Grand-Staircase Escalante National Monument are a number of noxious weeds for which the BLM mandates control. In addition to listed weeds are nonnative brome grasses [Bromus tectorum and Bromus rubens), which can potentially convert native ecosystems to biologic...Noxious weeds, Cheatgrass,1998
27 Ehleringer, James R.Seedling size and survival for Chrysothamnus nauseosusSeedling size and survival in relation to summer drought were examined for Chrysothamnus nauseosus growing under field and greenhouse conditions. In the field, summer survival rates were less than 2% annually for the three years monitored. The effect of initial seedling height on subsequent survival...Chrysothamnus nauseosus; Seedling size; Seedling survival1993
28 Hansen, Mark S.; Coffin, Cheryl M.; Capecchi, Mario R.Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.To investigate the role of the translocation-associated gene Pax3:Fkhr in alveolar rhabdomyosarcomas, we generated a Cre-mediated conditional knock-in of Pax3:Fkhr into the mouse Pax3 locus. Exploring embryonic tumor cell origins, we replaced a Pax3 allele with Pax3:Fkhr throughout its expression do...Neuroprogenitor; Embryogenesis2004-11-01
29 Capecchi, Mario R.Hox genes and mammalian developmentWe have examined the interactions of Hox genes in forming a cervical vertebrae, hindbrain, and limbs. In each case, it is apparent that individual Hox genes are performing individual functions but that more profound roles are apparent when they act in combination with others Hox genes. The observed ...Drosophila; Gene Expression Regulation, Developmental; Homozygote1997
30 Adler, Frederick R.Role of heterogeneity in the persistence and prevalence of sin nombre virus in deer miceMany diseases persist at a relatively low prevalence, seemingly close to extinction. For a chronic disease in a homogeneous population, reducing the transmission rate by a fraction proportional to the prevalence would be sufficient to eradicate the disease. This study examines how higher prevalence ...Transmission; Survivorship; Seropositivity2008
31 Ehleringer, James R.Carbon isotope discrimination and water relations of oak hybrid populations in southwestern UtahThe evergreen oak Quercus turbinella and the deciduous Q. gambelii form natural hybrids in southwestern Utah and northern Arizona. Hybrid individuals also are found in northern Utah in a region where only Q. gambelii currently exists, indicating that Q. turbinella has recently retreated southward. ...Quercus turbinella; Oak hybrids; Leaf structure; Leaf nitrogen; Carbon isotope discrimination; Water potential; Oak ecology2000
32 Gesteland, Raymond F.; Atkins, John F.; Ingram, Jennifer A.; Kelly, Paul J.; Grentzmann, GuidoDual-luciferase reporter system for studying recoding signalsA new reporter system has been developed for measuring translation coupling efficiency of recoding mechanisms such as frameshifting or readthrough. A recoding test sequence is cloned in between the renilla and firefly luciferase reporter genes and the two luciferase activities are subsequently measu...Amino Acid Sequence; Genes, Reporter; HIV; Antizyme; Translation1998
33 Capecchi, Mario R.; Bernstein, Kenneth E.; Thomas, Kirk R.Targeting genes for self-excision in the germ lineA procedure is described that directs the self-induced deletion of DNA sequences as they pass through the male germ line of mice. The testes-specific promoter from the angiotensin-converting enzyme gene was used to drive expression of the Cre-recombinase gene. Cre was linked to the selectable marker...Cre-recombinase; Hoxa3; Chimeric mice1999-06-15
34 Dawson, KyleSubaru FOCAS spectroscopic observations of high-redshift supernovaeWe present spectra of high-redshift supernovae (SNe) that were taken with the Subaru low-resolution optical spectrograph, FOCAS. These SNe were found in SN surveys with Suprime-Cam on Subaru, the CFH12k camera on the Canada-France-Hawaii Telescope, and the Advanced Camera for Surveys on the Hubble S...2010-01-01
35 Beckerle, Mary C.Comparison of three members of the cysteine-rich protein family reveals functional conservation and divergent patterns of gene expressionMembers of the cysteine-rich protein (CRP) family are evolutionarily conserved proteins that have been implicated in the processes of cell proliferation and differentiation. In particular, one CRP family member has been shown to be an essential regulator of cardiac and skeletal muscle development.LIM domains; Chicken fibroblasts; Zyxin; Actinin; Protein expression; Cysteine-rich proteins1997
36 Poulter, Charles DaleIsolation of Schizosaccharomyces pombe isopentenyl diphosphate isomerase cDNA clones by complementation and synthesis of the enzyme in Escherichia coliIsopentenyl diphosphate (IPP) isomerase catalyzes an essential activation step in the isoprene biosynthetic pathway. The Saccharomyces cerevisiae gene for IPP isomerase, IDI1, was recently isolated and characterized (Anderson, M. S., Muehlbacher, M., Street, I. P., Proffitt, J., and Poulter, C. D. (...Carbon-Carbon; Biosynthesis; Genetics1995-05-12
37 Ehleringer, James R.Gas exchange, δ13C, and heterotrophy for Castilleja linariifolia and Orthocarpus tolmiei, facultative root hemiparasites on Artemisia tridentataGas exchange and carbon isotope ratios were measured on 2 facultative hemiparasites, Castilleja linarifolia Benth. (Indian paintbrush; Scrophulariaceae) and Orthocarpus tolmiei I-I. & A. (Tolmie owl clover; Scrophulariaceae), and their Artemisia tridentata L. (big sagebrush; Asteraceae) hosts. Photo...Heterotrophy; Hemiparasite; Carbon isotope ratios; Shrub ecology; Castilleja linarifolia; Orthocarpus tolmiei; Artemisia tridentata1996
38 Ehleringer, James R.Intra- and interspecific variation for summer precipitation use in pinyon-juniper woodlandsIn the arid southwest of North America, winter precipitation penetrates to deep soil layers, whereas summer"monsoon" precipitation generally wets only surface layers. Use of these spatially separated water sources was determined for three dominant tree species of the pinyon-juniper ecosystem at six ...D/H ratios; Juniperus osteosperma; Pinus edulis; pinyon-juniper ecosystem; plant water sources; precipitation use; Quercus gambelii; roots; Photosynthetic gas exchange; Monsoon2000
39 Voth, Gregory Alan; Ayton, Gary S.Role of protein interactions in defining HIV-1 viral capsid shape and stability: a coarse-grained analysisCoarse-grained models of the HIV-1 CA dimer are constructed based on all-atom molecular dynamics simulations. Coarse-grained representations of the capsid shell, which is composed of approximately 1,500 copies of CA proteins, are constructed and their stability is examined. A key interaction between...Virus capsid; HIV-1; Viral capsid shape; Coarse-graining; CA dimer2010-01
40 Beckerle, Mary C.Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleusIntegrin-dependent cell adhesion to specific extracellular matrix molecules has been demonstrated to trigger dramatic changes in gene expression that can affect cell fate. However, little is understood about the molecular mechanism by which events at sites of cell-substratum adhesion are communicate...Zyxin; Cytosol; Nuclear export signal1997
41 Capecchi, Mario R.Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene.DNA sequences homologous to the v-abl oncogene were isolated from a Caenorhabditis elegans genomic library by their ability to hybridize with a v-src probe. The DNA sequence of 2465 nucleotides of one clone was determined. This region corresponds to the 5' protein kinase domain of v-abl plus approxi...Amino Acid Sequence; Animals; Base Sequence; Gene Expression Regulation; Transcription, Genetic1986-04
42 Capecchi, Mario R.Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase.We have examined the effect of cell cycle position on homologous recombination between plasmid molecules coinjected into synchronized rat fibroblasts. Recombination activity was found to be low in G1 and to rise 10- to 15-fold, peaking in early to mid-S phase.Cell Line; Kinetics; Plasmids1986-06
43 Sperry, John S.Cavitation fatigue - the weakening of cavitation resistance of xylem and its reversibilityXylem function is essential for the growth and survival of higher land plants. Xylem must not only be efficient under favorable conditions to facilitate high rates of stomatal conductance and carbon uptake, but it should also remain functional under drought conditions, when water potential (Ψ) dro...Cavitation fatigue; Drought; Pit membrane2003
44 Capecchi, Mario R.Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus.Implantation within the mammalian uterus elicits dramatic changes in the growth, differentiation, and morphogenesis of the conceptus. This process is interrupted in mice carrying a targeted disruption of the murine evx1 gene, a homolog of the Drosophila even-skipped (eve) gene. Upon implantation, pr...Extraembryonic; Homozygotes; Drosophila1994-08-15
45 Ehleringer, James R.; Rickart, Eric Allan; Dearing, Maria-DeniseStable isotope ratios (?15N AND ?13C) of syntopic shrews (SOREX)Local species richness in shrew (Soricidae) assemblages is often high, and the mechanisms of ecological separation remain relatively unexplored. In this study, hair samples from 6 species of Sorex in 3 separate assemblages were analyzed for stable carbon (13C/12C) and nitrogen (15N/14N) isotope rati...2004
46 Gussin, Gary N.; Capecchi, Mario R.Protein synthesis directed by DNA phage messengers.Even through the amino acids corresponding to most of the 64 nucleotide triplets are now known, several important aspects of the genetic code are not yet fully understood. In particular we need more knowledge about the "punctuation marks" of the code-for example, the signals necessary for the initia...Carbon Isotopes; Escherichia coli; Genetic Code; Methionine1967-09-01
47 Capecchi, Mario R.Gene targeting: an historical perspectiveOur entry into what was going to become the field of gene targeting began in 1977. I was experimenting with the use of extremely small glass needles to inject DNA directly into the nuclei of living cells. The needles were controlled by hydraulically driven micro-manipulators and were directed into n...Gene targeting -- History; Homologous recombination1998
48 Mattis, Daniel C.Theory of glass dynamics: the low-lying modes of anharmonic materialsWe study the lowest-lying excited states of arbitrary anharmonic solids (crystalline, glassy, or amorphous). Defining the harmonic ("skeleton") lattice underlying any such anharmonic medium, we find that its spectrum of elementary excitations provides a rigorous upper bound to that of the anharmonic...Spectrum; Arbitrary; Lattices1987
49 Coley, Phyllis D.; Kursar, Thomas A.Novel DNA-based microfluorimetric method to evaluate antimalarial drug activityThis paper describes the development of a novel microfluorimetric assay to measure the inhibition of Plasmodium falciparum based on the detection of parasitic DNA by intercalation with PicoGreen®. The method was used to determine parasite inhibition profiles and 50% inhibitory concentration values ...Microfluorimetric assay; Plasmodium falciparum; Chloroquine; Drug discovery2004
50 Adler, Frederick R.; Carrier, David R.Interaction between the X chromosome and an autosome regulates size sexual dimorphism in Portuguese Water DogsSize sexual dimorphism occurs in almost all mammals. In Portuguese Water Dogs, much of the difference in skeletal size between females and males is due to the interaction between a Quantitative Trait Locus (QTL) on the X-chromosome and a QTL linked to Insulin-like Growth Factor 1 (IGF-1) on the CFA...Phenotypes; QTL; Selection2005
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