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1 Hanes, JoshA comparison of nuclear thermal rockets with traditional chemical rockets for space transportThe Solar System has multiple destinations that private and governmental space agencies are planning to explore. Missions within the Solar System are both exorbitantly expensive and time intensive projects that involve high risks for the organizations involved. A mission that is currently being...Nuclear rockets - Research; Space vehicles - Design - Research; Nuclear thermal rockets; Chemical rockets; Space transport2016-04
2 Lee, Charles Chang SukA demonstration apparatus for optical pumping of rubidiumOptical pumping refers to the use of light in order to elevate ("pump") the spin (intrinsic angular momentum) of an atom or molecule. This process is of interest from a pedagogical and experimental perspective because it encapsulates fundamental properties of atomic physics and quantum mechanics. Fu...Optical pumping -- Research Spin exchange -- Research Rubidium isotopes -- Research2015-05
3 German, MassiellA genetic analysis of VSX2 function in the mouse eyeVsx2 is a homeodomain-containing transcription factor essential for maintenance of neuroretinal identity and neurogenesis. Vsx2 is believed to function via mechanisms that are strictly cell-intrinsic. However, recent research reveals evidence for involvement of Vsx2-mediated cell non-autonomous mech...Neurogenesis - physiology2012-05
4 Taggart, Maxwell M.A novel MRI-based screening method for assessing atrio-esophageal fistula risk following cardia ablationAtrio-esophageal fistulas affect 1 in 2000 patients who undergo cardiac ablation procedures with a mortality rate of 93%. Methods for detecting atrio-esophageal fistula formation that are objective and non-invasive could reduce the mortality associated with this disease. This study was performed ret...Magnetic resonance imaging; Cardia ablation; Trio-esophageal fistual2014-12
5 Simon, PhilipA study of the optimized load of a traveling wave thermoacoustic heat engineThermal interaction between differentially heated solid material and ambient gas in a resonator can lead to self-sustained oscillations or the transportation of heat in accordance with the thermoacoustic effect, first explained by Lord Rayleigh. In this research the phenomenon is employed in a lo...Thermoacoustic engine - Research; Energy conservation2016-03
6 Sullivan, Steven M.A trace formula for G2An n-dimensional matrix representation of a group G on a vector space V is a homomorphism from G to GL(V). For our purposes, we consider an irreducible representation to be a representation which cannot be decomposed into the direct sum of smaller-dimensional representations. Let H be a subgroup of ...Trace formulas2013-05
7 Blanton, Joseph P.AC Magnetic Susceptibility of Sub-Millimeter Superconductor Samples at Extreme ConditionsSuperconductivity is a unique state of matter observed at cryogenic temperatures in many materials. Superconductors are defined as materials that have zero DC electrical resistance and perfect diamagnetism below a critical transition temperature, Tc. These properties are very useful for many applica...2018
8 Arave, Rowan A.AKT1 activation promotes the development of melanoma metastasisMetastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT (or protein kinase B) signaling in human melanoma metastases led to the evaluation of the effect of activated AKT1 expression in non-metastatic BRAFV600E/cyclin dependent kinase inhibitor 2a nu...Melanoma - Genetics - Research; Metastasis - Genetics - Research; Biochemistry; Genetics2015-12
9 Shapiro, DarienActivation of transient receptor potential ankyrin-1 by wood smoke particulate materialExposure to wood smoke particulate matter (WSPM) has been linked to exacerbation of pre-existing respiratory conditions such as asthma, development of chronic obstructive pulmonary disease (COPD), and premature deaths. While it is clear that WSPM exposure is hazardous to human health, the molecular ...Smoke - Physiological effect2012-05
10 Zhu, JudyAnalysis of the pH-dependent equilibrium relationship between the guanine oxidation products 5-guanidinohydantoin and iminoallantoinOxidation of 2'-deoxyguanosine (dG) results in the major two-electron product 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG) that can undergo further oxidation to other products. One such product is 5-guanidinohydantoin (dGh) that is highly mutagenic and has been found in vivo. The ring architecture of d...Oxidation; guanine oxidation products; 5-guanidinohydantoin; Iminoallantoin; Equilibrium relationship2015-05
11 Edwards, Jennifer LynnApplication of a TBHP-mediated Wacker-type oxidation to internal alkenesThe Wacker oxidation allows access to methyl ketones from terminal alkenes. This transformation is important for industrial, synthetic, and medicinal chemists, as carbonyls are present in many natural and pharmaceutical products. With the carbonyl, a wide variety of reactions become available, such ...Wacker-type oxidatioin - Research; TBHP2013-05
12 Pecchia-Bekkum, AnnikaApplications of controlled DNA assembly and disassembly in biosensing and responsive drug deliveryDeoxyribonucleic acid (DNA) provides many exciting functions outside of simply encoding genetic information. Herein, we report two techniques to control the assembly and disassembly of nucleic acids. Within these techniques, DNA is used as a programmable material for biosensing and drug delivery. In...Nucleic acids - Biotechnology2013-08
13 Renz, AndyAssessment of exercise-stimulated tissue oxygenation in calf muscle with functional MRIPeripheral artery disease (PAD) affects millions of patients in the USA, and effective diagnosis and management of PAD is a major clinical goal. One promising avenue of research towards the goal is through functional MRI, which provides non-invasive measurement of tissue oxygenation. For a group of ...Arteries - Diseases - Diagnosis; Magnetic resonance imaging - Research; Calf muscle; Peripheral arterial disease; MATLAB2016-04
14 Estrada, JohannaBCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemiaCML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ...Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research2014-04
15 Burga, Carlos AlbertoBinary superlattices of semiconductor nanocrystals : a path towards possible high-temperature superconductivityThis thesis provides a platform to experimentally test Dr. Daniel Mattis' theoretical work on the possible superconductive behavior of nanostructured intrinsic semiconductors1-2. The theoretical work hinged on the nano-scale architecture of semiconductors. Therefore, using various types of semicondu...Semiconductor nanocrystals; Superconductivity; Superlattices as materials2013-05
16 Rose, StevenBiofuel cells for self powered arsenic detectionResearch in the Minteer group has centered on procedures for immobilizing enzymes and organelles on carbon electrodes for use in sensory and fuel cell applications. Similar strategies have been used to prepare a series of electrodes capable of pyruvate oxidation which, in the presence of arsenic, wi...Fuel cells; Arsenic - Detection2013-05
17 Ellingson, DrewBitangent lines to planar quartic curves in algebraic and tropical geometryBitangents are lines which are tangent to a curve at two points. The bitangents of a classical quartic are well understood, and a result originally due to Cayley tells us that there are always precisely 28 bitangents to a generic quartic plane curve. When looking at Tropical Geometry, the situation ...Tropical geometry; Curves, Quartic; Curves, Algebraic; Bitangents2015-04
18 Simonsen, KyleBreast cancer knowledge and attitudes among women in ArmeniaBackground: Breast cancer, the most common invasive cancer among women, has high incidence and mortality rates among women in the Republic of Armenia. Advanced stage at detection limits treatment options and contributes to high morbidity and mortality. Understanding women's breast cancer knowledge a...Breast - Cancer; Breast - Cancer - Patients - Attitudes; Breast - Cancer - Patients - Armenia (Republic)2013-07
19 Thomas, NikitaCellular ultrastructure of C. elegans nervous systemDetermining the ultrastructural organization of the nervous system is a key step in understanding how complex behavior is generated. For a nervous system to function, it must be wired accurately. A complete wiring diagram, referred to as a connectome, can be created by tracing neuronal profiles thro...Caenorhabditis elegans - Nervous system2013-05
20 Gondolo, AlessandroCharacterization and Synthesis of Rayleigh Damped Elastodynamic NetworksWe consider damped elastodynamic networks where the damping matrix is assumed to be a non-negative linear combination of the stiffness and mass matrices (Rayleigh damping). We give here a characterization of the frequency response of such networks. We also answer the synthesis question for such netw...Damping (Mechanics) - Mathematics2013-05
21 Visser, JoshuaCharacterization of G-quadruplexes in DNA repair protein gene sequences and the effects of oxidized guanine lesions on DNA base insertion and elongationGuanine (G) is one of the four nucleo bases that make up the complex macromolecule deoxyribonucleic acid (DNA). In addition to its ability to Watson-Crick base pair with cytidine (C), guanine can base pair with itself vianon-canonical, Hoogsteen base pairing and form a secondary structure of DNA ca...DNA repair - Research; G proteins - Pathophysiology - Research; Oxidation, Physiological - Research; Membrane homogenization; Synthetic blood; Artificial oxygen carriers2016-05
22 Bell, MarisaCharacterization of Polyphenols in I. UmbelliferaSecondary metabolites in plants, including polyphenolics, may be responsible, in part, for diversity in the tropics. Variation in chemical defense among species of trees encourages specificity in herbivorous insects. Due to the short lifespan of insects compared to trees, diversity in chemical defen...2018
23 Barbeau, WilliamCharacterization of a New Ribosome Associated Quality Control PathwayProteins are life's double edged sword. Proteins are essential macromolecules of life, and the tasks that some proteins accomplish are quite marvelous. At the same time, if proteins misfold they have the potential to kill the cell that harbors them. It is becoming increasingly clear that proteins ha...Ribosomes - Research2016-12
24 Nicolo, TeraCharacterization of mitochondria-modified electrodesIn order to develop an herbicide sensor, yeast, potato, and bovine heart mitochondria were isolated and immobilized onto Toray paper electrodes. Cyclic voltammetry showed two redox peaks at 186 ± 14 mV vs. SCE and -357 ± 24 mV vs. SCE with an E1/2 of -128 mV. Scan rate studies suggested the proces...Electrodes; Herbicides - Detection2013-05
25 Little, Nancy AnnCharacterizing and mapping l(3)7E103 a gene required for Drosophila dorsal closureDorsal closure in the fruit fly Drosophila melanogaster is a complex morphogenetic process dependent upon three embryonic tissues: the lateral epidermis, leading edge epidermis, and amnioserosa. Additionally, the Jun N-terminal Kinase (JNK) and Decapentaplegic (Dpp) signaling cascades are required f...Drosophila melanogaster - Genetics; Drosophila melanogaster - Embryology2013-05
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