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Creator | Title | Description | Subject | Date |
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Ridge, Rachel Katherine | Flagellar Protein Flhe Influences Motility and Morphology Through Regulation of Assembly in Escherichia Coli | The bacterial flagellar motor is a remarkably complex system, comprising thousands of protein subunits and responsible for motility in numerous species. Of these proteins, FlhE is not universally conserved and is relatively understudied. Usually found cotranscribed with flhB and flhA in the flhBAE o... | | 2017 |
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Cocke, Rebecca C. | Evaluating the Catalytic Activity of Iron and Nickel Impurities in Bare High-Pressure High-Temperature Nanodiamond | Many metal nanoparticles are used as catalysts for various reactions and are held on supports. High-Pressure High-Temperature nanodiamonds (HPHT ND) are able to support metal nanoparticles even under strenuous chemical environments due to their robust nature. The production of HPHT ND includes the u... | | 2018 |
3 |
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Capener, Jacob | G Protein-Coupled resecptor kinase 2 mediated phosphorylation for The Activation of Smoothened | The Hedgehog (Hh) pathway is a cell signaling pathway that is involved in embryonic development and adult tissue maintenance in vertebrates. Improper functioning of this pathway can lead to developmental disorders and several forms of cancer. Despite the pathway's biological importance, the transduc... | | 2020 |
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Borodai, Anastasia S. | Faraday @ Home Continuing Faraday from the "U" to the Youth | Recent attention has been brought to light in the United States regarding the lack of students pursuing STEM disciplines and degree programs. There is a considerable amount of research on the importance of STEM (Science, Technology, Engineering and Math) Education at an early onset age. With this is... | | 2017 |
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Coplan, Caitlin Denise | Fabrication and Application of Aluminum Nanostructures | Plasmonics, the phenomenon resulting from light interactions with nanoscale structures, is an active field for nanoscale manipulation of light. By varying the metal, size, and shape, plasmonic nanostructures can be tuned to interact with a broad spectral range of light. Commonly used plasmonic mater... | | 2019 |
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Olsen, Nicholas | Simple Molecular Models for Chiral Crystallization | Chiral molecules play an important role in many biological processes.1 Important chiral biomolecules include certain amino acids, sugars, DNA, RNA, and many proteins. Chiral molecules have enantiomers, mirror-image isomers that cannot be superimposed on each other. The classic analogy to enantiomers... | | 2020 |
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Scholl, Wallis | Nanomite-Decorated Nanoparticles as Surface-Enhanced Spectroscopy Substrated | Surface-enhanced spectroscopy substrates utilize the localized surface plasmon resonance of nanoparticles for optical, photocatalysis, and biological and chemical sensing applications. Plasmonic anisotropic nanoparticles with sharp tips focus the electromagnetic field of the localized surface plasmo... | | 2020 |
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Farrall, Nicholas | Structural characterization of the full-length exocyst complex by transmission electron cryo-microscopy | The exocyst is a conserved octameric protein complex in eukaryotes that is essential for tethering and fusion of vesicles to the plasma membrane. Composed of eight subunits, it is essential for growth, secretion, and developmental processes and has been implicated in cell motility, autophagy, cell d... | Saccaromyces cerevisaie - Cytology; Cryomiscroscopy - Research | 2014-05 |
9 |
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Fox, Zach | The physical effects of solvent in molecule-based magnets | Molecule-based magnets are being studied in order to expand the utility of magnets in modern devices. Advantages of molecule-based magnets include less energy intensive synthesis and greater versatility through changes to organic components of the structure. This class of materials is studied to ena... | Magnets - Experiments | 2012-05 |
10 |
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Zurbuchen, Rudi | Macrocyclization of glucagon-like peptide (GLP-1) by thiol-ene reaction | Macrocyclization of peptides helps maintain a stable alpha helical structure using a conformational constraining staple. One such peptide, glucagon-like peptide-1 (GLP-1), is a 37 amino acid peptide agonist for the GLP-1 receptor and has the ability to lower blood glucose levels and is responsible ... | Peptide hormones - Receptors - Research; Ring formation (Chemistry) - Research; Macrocyndization; GLP-1; Swim kinematics; Pre-pulse inhibition | 2016-05 |
11 |
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Cantrell, Rachel Lou-La Vonne | Synthesis of Antibiotic Scaffolds Inspired by the Tan 1057-D Biologically Active Natural Product Through the Utilization of Ullmann Copper(I) and Gold Cyclization Chemistry | As bacterial resistance to drugs continues to rise, the search for new antibiotics is of paramount importance. One key element to finding successful antibiotics is to uncover small molecules that act through novel mechanisms of action in order to decrease the risk of cross-resistance and provide ant... | | 2020 |
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Duffin, Calder | Sequence Activity Relaqtionships in a Radical Sam Peptide Maturase | Ribosomally synthesized and post-translationally modified peptide Tte1186a and several point mutation variants are synthesized using solid phase peptide synthesis with FMOC amino acids. Substrate recognition and thioether linkage formation from the radical S-adenosyl methionine Tte1186 maturase is d... | | 2020 |
13 |
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Munn, Jackson | Determining microbial community composition and methane flux or red butte canyon sediment over time | Methane is a potent greenhouse gas that is released from the soil into the atmosphere, which contributes heavily to global warming. One potential way of reducing the amount of methane in the air is through studying methane consuming bacteria (methanotrophs) and how they interact with other microbes ... | | 2022 |
14 |
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Rose, Steven | Biofuel cells for self powered arsenic detection | Research in the Minteer group has centered on procedures for immobilizing enzymes and organelles on carbon electrodes for use in sensory and fuel cell applications. Similar strategies have been used to prepare a series of electrodes capable of pyruvate oxidation which, in the presence of arsenic, wi... | Fuel cells; Arsenic - Detection | 2013-05 |
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Burga, Carlos Alberto | Binary superlattices of semiconductor nanocrystals : a path towards possible high-temperature superconductivity | This thesis provides a platform to experimentally test Dr. Daniel Mattis' theoretical work on the possible superconductive behavior of nanostructured intrinsic semiconductors1-2. The theoretical work hinged on the nano-scale architecture of semiconductors. Therefore, using various types of semicondu... | Semiconductor nanocrystals; Superconductivity; Superlattices as materials | 2013-05 |
16 |
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Zhu, Judy | Analysis of the pH-dependent equilibrium relationship between the guanine oxidation products 5-guanidinohydantoin and iminoallantoin | Oxidation of 2'-deoxyguanosine (dG) results in the major two-electron product 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG) that can undergo further oxidation to other products. One such product is 5-guanidinohydantoin (dGh) that is highly mutagenic and has been found in vivo. The ring architecture of d... | Oxidation; guanine oxidation products; 5-guanidinohydantoin; Iminoallantoin; Equilibrium relationship | 2015-05 |
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Edwards, Jennifer Lynn | Application of a TBHP-mediated Wacker-type oxidation to internal alkenes | The Wacker oxidation allows access to methyl ketones from terminal alkenes. This transformation is important for industrial, synthetic, and medicinal chemists, as carbonyls are present in many natural and pharmaceutical products. With the carbonyl, a wide variety of reactions become available, such ... | Wacker-type oxidatioin - Research; TBHP | 2013-05 |
18 |
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Odendahl, Nathan | Comparison of popular force fields for molecular modeling of proteins applied to ice binding of the tenebrio molitor antifreeze protein | Ice Binding Proteins (IBPs) are a class of proteins that affect the melting and freezing temperatures of ice. While substantial research has been conducted to understand the properties of IBPs, experimental and molecular dynamics simulations have not satisfactorily explained the mechanism of the i... | Antifreeze proteins - Research; Ice binding proteins; Tenebrio molitor; Antifreeze protein; Force fields | 2016-04 |
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Peterson, Joseph Ryan | Deflagration and detonation modeling of heterogeneous condensed phase explosives | A modeling approach to the deflagration and detonation phenomena is employed to study a variety of explosive scenarios. An engineering model for macroscale reaction of energetic materials over the wide range of explosive reaction from deflagration to detonation is developed based upon solid foundati... | Deflagration phenomena; Detonation phenomena; mesoscale model | 2012-05 |
20 |
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Lim, Koun (Kasha) | Deglycoyslation of glucose oxidase and its application within high power enzymatic fuel cells | To compensate for the increase of carbon dioxide level and the energy exhaust, an enzymatic fuel cell (EFC) has been investigated by researchers. In the paper, a chemical oxidative deglycosylation of an enzyme was investigated to furture improve EFCs. By deglycosylating an enzyme, the distance betwe... | Fuel cells - Research; Electric power - Research; Deglycosylation; Enzymatic fuel cell; Glucose oxidase | 2016-04 |
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Ballif, Micah | Drugs and Pregnancy: Clinical Management with a Cystic Fibrosis Focus | Despite the large number of women who become pregnant and use a medication during their pregnancy, there is very little information about the safety of the majority of medications. Most drugs approved by the FDA have undetermined teratogenic risk, but their use is prevalent in the management of dise... | | 2019 |
22 |
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Sanders, Sara | Development of a novel, coumarin-europium sensor for reactive oxidizing species | The synthetic framework has been developed for two fluorescent probes of Reactive Oxidizing Species (RoxS) based on a coumarin-europium fluorescence pair. The coumarin moiety's selectivity for hydrogen peroxide coupled with 620 nm shifted emission of the europium will make these novel sensors biolog... | Reactive Oxygen Species - analysis | 2012-05 |
23 |
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Franchina, Jordan Avery | Measurement of bond dissociation energies of transition metal molecules | Measuring thermochemical and kinetic properties of chemical systems has always; been a central theme of chemistry. Knowing these properties assists us in assessing; whether or not a chemical reaction is energetically feasible, efficient, and worthwhile.; Theoretical chemistry has now developed suffi... | Chemical systems; thermochemical; kinetic; modeling | 2018-04 |
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Aderibigbe, Justis | Trends in the usage of bidentate phosphines as ligands in nickel catalysis of hydrogenation reactions | A critically important process in catalysis is the formation of an active catalyst from the combination of a metal precursor and a ligand, as the efficacy of this reaction governs the amount of active catalyst. This review is a compacted but comprehensive review of reactions catalyzed by nickel and ... | | 2021 |
25 |
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Arnoholt, Alayna | An analysis on the influence of anxiety in post error slowing | Anxiety disorders are among the most common mental disorders and affect 15.7 million Americans each year (Lépine, 2002, p. 4). Anxiety is associated with reduced productivity, physical distress, and other diseases such as depression. Anxiety could also be influential in error response (Compton et a... | | 2021 |