Honors Theses Open Access
 
Filters: School Or College: "College of Engineering" Collection: "ir_htoa" Year End: 2017
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1 Taggart, Maxwell M.A novel MRI-based screening method for assessing atrio-esophageal fistula risk following cardia ablationAtrio-esophageal fistulas affect 1 in 2000 patients who undergo cardiac ablation procedures with a mortality rate of 93%. Methods for detecting atrio-esophageal fistula formation that are objective and non-invasive could reduce the mortality associated with this disease. This study was performed ret...Magnetic resonance imaging; Cardia ablation; Trio-esophageal fistual2014-12
2 Gilbert, JohnA novel tool to capture neural activity across an entire brain using C-FOS as an indicatorImmunohistochemical staining for the expression of the immediate early gene c-Fos is a powerful tool to measure neuronal activation of neurons across an entire brain. The results of c-Fos immunostaining are often quantified by counting the number of immunolabeled cells in a region of interest (ROI) ...Brain - Localization of functions - Research; Brain - Physiology - Research; Brain mapping - Research; Memory - Research; Mice as laboratory animals - Research; Brain activity; Immunohistochemical staining2016-05
3 Jackson, Dale JayAerodynamic mixing losses and discharge coefficients due to film cooling from a symmetric turbine airfoil in transonic flowAerodynamic losses and discharge coefficients are obtained for two different Pratt and Whitney axisymetric turbine airfoils with film cooling holes. Blade 3 results are given for the blowing ratios, of 0.42, 0.73, and 1.28. The pressure ratios are 1.18, 1.45, and 2.07 for the "ambient" tests and 1.1...Mechanical Engineering1998-12
4 Loftus, Patrick D.Agonist binding of herg K+ channels inhibits epithelial cell extrusion but not apoptosis in MDCK monolayers; providing possibilities to cancer metastasis regulationMetastasis is commonly referred to as cancerous cell movement from an original site to one or more sites elsewhere in the body. When these moving cancerous cells are malignant, an individual's chance of survival is decreased. In order for epithelial cells to move they are detached from the epitheliu...Biomedical Engineering2012-01
5 Meier, John E.An evaluation of the quality of contemporary ray tracing methods on architectural materialsPredictive computer graphics can be used to visualize the appearance of an object or scene from a virtual design. A seminal experiment in that field was performed in 1984 to evaluate the perceptual quality of computer graphics images with a physical model of the scene. The original study was limited...Ray tracing algorithms2009-05
6 Sharma, KapilAnalyzing the relationship between PDM2 and B-catenin proteins in human cancersTumorigenesis is promoted by the manipulation of several co-factors and pathways, in which PKM2 and P-catenin proteins play a significant role in a variety of cancers. New research states that these two hegemonic cancer proteins directly bind with each other and may provide a new angle for cance...Pyruvate kinase - Research; Tumorigensis - Research2016-04
7 Anjewierden, ScottAutomated kinematic analysis of pre-pluse inhibition in larval zebrafishAnimals differentially ignore or attend to sensory information depending on their immediate environment. A significant example of this phenomenon is audiomotorpre-pulse inhibition (PPI), in which the startle response to a loud noise is suppressed by a preceding stimulus of lower intensity. This a...Zebra danio - Development; Kinematics - Research; Kinematic parameters; Swim kinematics; Pre-pulse inhibition2014-12
8 Eccles, Patrick NolanThe Cabal reflection: A post mortem of an entertainment arts and engineering capstone projectThis document will serve as Patrick Eccles' Honors Thesis at the University of Utah and will reflect upon the process and result of his and his team members' senior project within the Entertainment Arts and Engineering program: the 3D Puzzle Platformer A Divided Light . On the senior project team, P...Computer games - Design; Cabal Process2015-08
9 Gilbert, AndrewComputational modeling of the rat hippocampus for improving neural stimulationNeural prostheses are used to restore some level of function to tissue damaged by disease. It is important to model and correctly identify the relationship between electrical stimulation and neural response to provide a framework for prosthetic stimulation. This work will show a struc...Neural stimulation - Research; Hippocampus (Brain) - Research; Memory - Research; Rats as laboratory animals - Research; Neural prosthetic2016-05
10 Young, MichaelThe Contributions of Elastin to Ligament ViscoelastictyLigaments exhibit viscoelastic behavior in response to strain. This behavior protects joints from injury during loading. Collagen is the primary structural component of ligaments, but does not account fully for the viscoelastic behavior. Elastin is another structural protein in ligaments, and provid...2017
11 Bracken, KallieDefining learning: mystifying machine learning as a powerful tool in a data-driven worldUntil recently, the driving paradigm in software engineering has been to design applications for a predefined set of tasks. This approach, however, is quickly being dwarfed by data-driven applications which are designed to use knowledge and understanding to decide how they can best fulfill use...Machine learning - Case studies; Machine learning - Study and Teaching; Machine Learning - Technique2016-04
12 Zubair, JonathanDesign and Implementation of a Shrouded Rotor for Uncreasing Quadrotor PerformanceQuadrotors have come to serve myriad purposes and have seen use as platforms for diverse activities including videography and remote sensing. These versatile aircraft, however, cannot remain in flight for extended periods of time. This is due to several factors including the aerodynamic regime in wh...2017
13 Robe, John WilliamThe Design and Implementation of Autonomous Robotic SystemsThis research focuses on the development of an autonomous robotic system using Robot Operating System (ROS), with the purpose of competing in the NASA Robotic Mining Competition in collaboration with the Utah Robotic Mining Project team. While completing this research, the following discoveries were...2017
14 Hopkins, JacobDesign of a novel pediatric adaptive skiing systemAdaptive sports and recreational rehabilitation provide patients with experiences that cannot be achieved in a hospital or clinic. Of the many forms of adaptive equipment designed for children, only a few adaptive skiing systems are available and none are specifically designed for convenient adjusta...Skiing for people with disabilities - Research; Adaptive skiing technology; Adaptive sports; recreational rehabilitation2016-05
15 Matheson, KristofferDesign of a novel x-ray CT in situ experiment for imaging 3D deformation of aluminum foam materialsOpen-cell metallic foams show excellent potential for lightweight load-bearing structural applications, electrodes in energy-storage devices, biomedical implants, and heat exchangers, to name a few. A key aspect in efficient and streamlined deployment of aluminum foams for these applications lie...Foamed materials - Testing; Tomography - Research; Lightweight materials - Research; X-ray computed tomography; Aluminum foam materials; Load frame2016-04
16 Gajiwala, SnehalDetermining the variability of depressive brain circuitry among healthy subjects for deep brain stimulationDeep Brain Stimulation (DBS) is being evaluated to treat Treatment-Resistant Depression, though it has shown mixed results. We believe that variability within the fiber tracts of the brain may account for these outcome differences. In this study, we attempt to characterize this potential variation....Brain stimulation - Therapeutic use - Research; Depression, Mental - Treatment - Research; Deep brain stimulation; Depressive brain circuitry; Fiber tracts; Tractography2016-05
17 Luo, ShirleyDevelopment of a bioabsorbalbe active release antimicrobial coating for orthopedic implantsOrthopedic implantations often create an opportunity for biofilm-related infections to arise. Patients infected with biofilm must often undergo additional surgeries for repair or replacement, which puts them at a greater risk of osteomyelitis, sepsis, and other complications including death [17]. T...Orthopedic implants - Research; Anti-infective agents - Research; Staphyloccoccal infections - Prevention and control - Research; Antimicrobial coating; Staphylococcus aureus2016-05
18 Rahislic, EmirDevelopment of a Copper-Based Oxygen Carrier for Chemical Looping with Oxygen UncouplingChemical looping with oxygen uncoupling (CLOU) is a CO2-capture technology that is a special form of chemical looping combustion (CLC). It requires an oxygen carrier that cycles between two reactors picking up oxygen from one and delivering it to another for the combustion of solid fuels. An oxygen ...2017
19 Feliciano, Jeppesen GarciaDevelopment of Computational Strategies for Improved Environmental Simulations of Water Energy Balances, Air Quality, and Energy UseIn the last decade, there has been more focus on urban microclimate due to concerns for inhabitants' health, water and energy resource consumption, and air quality. The Green Environmental Urban Simulations for Sustainability (GEnUSiS) project uses large computational platforms including the Quick U...2017
20 Hyer, Christina CottrellEffect of M1 Matrix Protein on Hemagglutinin Expression and Influenza Virus-Like Particle Production in Trichoplusia NIVirus-like particles (VLPs) are a new and effective flu vaccine approach. VLPs are non-infectious and can produce robust immune responses. Flu VLPs are typically created by co-expressing the flu hemagglutinin (HA) surface antigen and the matrix protein M1-which assists in viral and VLP budding-in cu...2017
21 Grimmett, RollinEffects of Hypoxia and High Fat Diet on D. Melanogaster Heart PhysiologyHeart disease severely affects millions of people worldwide, and is caused by various environmental and genetic factors. The aim of this study is to examine the combined physiological effects of hypoxia and a high fat diet (two known causes) on Drosophila Melanogaster heart structure. Sets of adult ...2017
22 Ruan, TingEndogenous ceramide contributes to cardiovascular complications in Type II diabetes by decreasing the association between PP2A and I2PP2ACardiovascular complications are the leading cause of death in individuals with conditions associated with insulin resistance, e.g. type 2 diabetes, diet-induced obesity. In patients with type 2 diabetes, cardiovascular complications are 2-4 times more prevalent. One common cardiovascular complicati...Ceramides - Physiological effect; Diabetic angiopathies2014
23 Flach, BrianExamining the effects of whisker trimming on mouse brain cell growthHoxb8 microglia are a particular breed of scavenger cells in the brain which have been related to obsessive compulsive disorder (OCD)-like behavior among other behavioral disorders. These cells have been found to reach full maturity during a period of neurological development known as the critical ...Obsessive-compulsive disorder - Research; Microglia - Research; Mice as laboratory animals - Research; Whiskers; Scavenger cells; Hoxb8 microglia2016-04
24 Waller, Rosalie G.Exome sequence comparison of seventy-seven multiple myeloma cases identifies potential risk allelesMultiple Myeloma (MM) is a heritable cancer of plasma cells with poor prognosis. Although a few genomic risk-loci have been identified for MM, no risk variants have been published that explain MM heritability. We hypothesize MM heritability is due to rare germ-line variants that can be discovered th...Multiple myeloma -- Genetic aspects; Exomes; Exome sequence; Risk alleles2015-05
25 Mroz, MaxExploration of Magnetic Field Actuated Strings of Spherical Magnets for Swimming Robot LocomotionRobots capable of operating in fluid have a variety of applications from biomedical devices to use in piping systems for monitoring and inspection. If these robots can be driven remotely by methods other than traditional motors, they can be less technologically complex, safer and more durable. The f...2017
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