Honors Theses Open Access
 
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1 Wang, Karissa M.Transcription factor NFATc1's signaling pathway and role in cardiomyocyte functionAtrial fibrillation (AF) is the most common sustained arrhythmia. It affects as many as 6.1 million people in the United States and increases their risk of stroke by 4-5 times. AF is evidently a very serious condition, but the scientific community does not yet fully understand its underlying mechani...2020
2 Santos, Jean Paul DytiocoFlight control systems with optimal effector allocation accounting for load constraintsThis paper describes the development of quadratic optimization algorithms to be used in flight control systems; such optimization algorithms aid in distributing control efforts among available actuators to produce forces to keep aircraft stable and in flight. With the advancement of computing power,...Flight control; Algorithms2013-05
3 Schlegel, Isabelle B.Peptide-fab conjugates to improve treatment of neovascular age-related macular degenerationAge-Related Macular Degeneration (AMD), a chronic disease of the eye and leading cause of blindness in Americans over 50, is often treated with agents that inhibit Vascular Endothelial Growth Factor (VEGF). Ranibizumab is an anti-VEGF antibody fragment (Fab) effective at treating over 90% of AMD pat...2021
4 Gilbert, AndrewComputational modeling of the rat hippocampus for improving neural stimulationNeural prostheses are used to restore some level of function to tissue damaged by disease. It is important to model and correctly identify the relationship between electrical stimulation and neural response to provide a framework for prosthetic stimulation. This work will show a struc...Neural stimulation - Research; Hippocampus (Brain) - Research; Memory - Research; Rats as laboratory animals - Research; Neural prosthetic2016-05
5 Radhakrishnan, SridharanDevelopment of Low-Cost system for Myoelectric Prosthesis ControlThe upper limb prosthetics field has advanced to where artificial hands can mimic human motions based on electrical signals emitted from muscular activation and can even open and close proportionate to the amplitude of signal they receive. However, these prostheses are very expensive, with some cost...2020
6 Lusted, KitselTemperature dependence of leptospirillum ferriphilum during biooxidation of pyriteRare earth elements have properties that make them useful in advanced electronics, magnets, and batteries. However, they are difficult to isolate from their constituent elements, which results in an environmentally costly operation to refine them. An environmentally friendly alternative extraction m...2023
7 Ingold, AlexanderDevelopment of a Utah optrode array for large scale optogenetics in non-human primate cortex: analysis of spatial excitation pattern using C-FOS expressionA central goal in neuroscience is to understand how neural circuits generate the computations that underlie neuronal responses, sensory perception, and behavior. This requires manipulating their activity and determining the results of these manipulations. Optogenetics is a versatile laboratory techn...2022
8 Abraham, Jacob Isaac KalunakaaheleOptimization of hydraylic fracturing of tight gas formations in horizontal wellsThe discoveries of significant resources of oil and gas in the Barnett, Bakken, Marcellus, and other shale formations have presented an opportunity for national petroleum independence and possible export in the relatively near future. These formations are considered to be "unconventional" resources ...Hydraulic fracturing2013-04
9 Dibble, Alicia G.Computer Simulation-Aided Design of Single-Ion Conducting Structures for Solid Polymer Electrolytes in Lithium0ion BatteriesLithium-ion batteries are commonplace in consumer devices, but the volatility of the liquid electrolyte used in those batteries poses an innate safety risk that must be combated if the batteries are to maintain their preferential status in modern technology. One alternative to liquid electrolytes is...2019
10 Anjewierden, ScottAutomated kinematic analysis of pre-pluse inhibition in larval zebrafishAnimals differentially ignore or attend to sensory information depending on their immediate environment. A significant example of this phenomenon is audiomotorpre-pulse inhibition (PPI), in which the startle response to a loud noise is suppressed by a preceding stimulus of lower intensity. This a...Zebra danio - Development; Kinematics - Research; Kinematic parameters; Swim kinematics; Pre-pulse inhibition2014-12
11 Kennedy, AshleyDesign of Optimal Carbonaceous Material from Carbon Capture for Use in Lithium-Ion BatteriesThe utilization of carbon nanofiber obtained from carbon capture as a potential anodic material in lithium-ion batteries was investigated in this project. The carbon nanofiber obtained from the carbon capture process was designed to be optimal for use in lithium-ion batteries. Its suitability as an ...2018
12 Koblanski, KasperLiver foxn3 increases pancreatic a-cell mass without altering hepatic amino acid utilizationInsulin injection into peripheral tissues inefficiently controls elevated fasting blood glucose in type 1 diabetes mellitus (DM1) patients. Peripheral insulin lacks the signaling of healthy β-cell insulin, which directs adjacent pancreatic α-cells to stop production of glucagon, a hormone releasin...2022
13 Sivo, JacobAgile in the Wild - An in-Depth look into EAE Student Development PracticeThere have been works produced on Agile techniques and their e#11;ectiveness in terms of both actual project progress as well as human factors, especially in industry. There are many training programs that companies enroll their employees in, such as ASPE. In these training programs, individuals are...2019
14 Tripathy, AnuragNickel-Functionalized Solid-State Titania Nanotube Array for the Electrochemical Detection of Breath-Based Biomarkers in Colorectal CancerColorectal cancer (CRC) is the second most common cancer in the United States with approximately 137,000 new cases each year, 50,000 of which are fatal due to belated screenings [1]. The gold-standard detection method is colonoscopy, a direct visualization tool that facilitates the removal of minor ...2019
15 Harding, Anna NeiblingLow-Cost Surface Electromyogtraphy Sleeve for Quick and Repeatable Decoding of Motor IntentSurface electromyography (sEMG) is a noninvasive way to decode motor intent for applications such as prosthesis control, virtual reality, and stroke or spinal cord rehabilitation. State-of-the-art methods of decoding motor intent used in myoelectric prostheses have limited capabilities, partially du...2019
16 Lietzke, StephanieRemoval of endotoxins from recombinant antithrombinEndotoxins (also known as lipopolysaccharides or ETs) are a pyrogenic byproduct of the breakdown of gram-negative bacterial cell-walls, such as E. coli. They cause fever and septic shock in humans, and are therefore highly regulated by the FDA and USP. ETs are a common contaminant in recombinant pr...Endotoxins - Research; Antithrombins - Therapeutic use; Sheep as laboratory animals - Research; endotoxin removal; Angiogenesis2016-04
17 Downs, MelindaModeling conductivity as a function of temperature for CZTS and CZTSe thin film solar cell absorber layersThe goat of this project was to develop an accurate model for the temperature dependent conductivity of CU2ZnSnS4 (elTS) and CU2ZnSnSe4 {ClTSe} thin film solar cell absorber layers. Mathematical models of conductivity and resistivity were derived from both parallel and series combinations of tempera...Solar cells; Thin films2013
18 Traction estimation and control for mobil robots using wheel slip velocityMobile robots are used to venture through types of environments, at low wheel speeds, where wheel slip is a threat. Wheel slip is a hazard to mobile robots in that it introduces error in dead reckoning measurement and in some instances causes the robot to halt its forward progress. To compensate ...Robots; Motion;Traction2008-12
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