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| Creator | Title | Description | Subject | Date | ||
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Gerig, Guido | A new framework for analyzing white matter maturation in early brain development | The trajectory of early brain development is marked by rapid growth presented by volume but also by tissue property changes. Capturing regional characteristics of axonal structuring and myelination via neuroimaging requires analysis of longitudinal image data with multiple modalities. Complementary ... | 2010-01-01 | |
| 2 |
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Gerig, Guido | Brain volumes in psychotic youth with schizophrenia and mood disorders | Background: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br... | 2010-01-01 | |
| 3 |
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Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | 2010-01-01 | |
| 4 |
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Gerig, Guido | Evaluation of DTI property maps as basis of DTI atlas building | Compared to region of interest based DTI analysis, voxel-based analysis gives higher degree of localization and avoids the procedure of manual delineation with the resulting intra and inter-rater variability. One of the major challenges in voxel-wise DTI analysis is to get high quality voxel-level c... | 2010-01-01 | |
| 5 |
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Gerig, Guido | Image registration driven by combined probabilistic and geometric descriptors | Deformable image registration in the presence of considerable contrast dierences and large-scale size and shape changes represents a signicant challenge for image registration. A representative driving application is the study of early brain development in neuroimaging, which requires co-registratio... | 2010-01-01 | |
| 6 |
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Gerig, Guido | Multi-object analysis of volume, pose, and shape using statistical discrimination | One goal of statistical shape analysis is the discrimination between two populations of objects. Whereas traditional shape analysis was mostly concerned with single objects, analysis of multi-object complexes presents new challenges related to alignment and pose. In this paper, we present a methodol... | 2010-01-01 | |
| 7 |
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Gerig, Guido | Quality control of diffusion weighted images | Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple dire... | 2010-01-01 | |
| 8 |
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Gerig, Guido | Spatio-temporal analysis of early brain development | Analysis of human brain development is a crucial step for improved understanding of neurodevelopmental disorders. We focus on normal brain development as is observed in the multimodal longitudinal MRI/DTI data of neonates to two years of age. We present a spatio-temporal analysis framework using Gom... | 2010-01-01 | |
| 9 |
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Gerig, Guido | Towards analysis of growth trajectory through multi-modal longitudinal MR imaging | The human brain undergoes significant changes in the first few years after birth, but knowledge about this critical period of development is quite limited. Previous neuroimaging studies have been mostly focused on morphometric measures such as volume and shape, although tissue property measures rela... | 2010-01-01 |
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