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CreatorTitleDescriptionSubjectDate
1 Gerig, GuidoAbnormal brain synchrony in down syndromeDown Syndrome is the most common genetic cause for intellectual disability, yet the pathophysiology of cognitive impairment in Down Syndrome is unknown. We compared fMRI scans of 15 individuals with Down Syndrome to 14 typically developing control subjects while they viewed 50 min of cartoon video c...2013-01-01
2 Gerig, GuidoDiffusion imaging quality control via entropy of principal direction distributionDiffusion MR imaging has received increasing attention in the neuroimaging community, as it yields new insights into the microstructural organization of white matter that are not available with conventional MRI techniques. While the technology has enormous potential, diffusion MRI suffers from a uni...Diffusion magnetic resonance imaging; Diffusion tensor imaging; Quality assessment; Entropy2013-01-01
3 Gerig, GuidoFiber tract-oriented statistics for quantitative diffusion tensor MRI analysisDiffusion tensor imaging (DTI) has become the major modality to study properties of white matter and the geometry of fiber tracts of the human brain. Clinical studies mostly focus on regional statistics of fractional anisotropy (FA) and mean diffusivity (MD) derived from tensors. Existing analysis t...Diffusion tensor interpolation, Diffusion tensor statistics, DTI analysis, Fiber tract modeling2006-01-01
4 Gerig, GuidoGroup analysis of DTI fiber tract statistics with application to neurodevelopmentDiffusion tensor imaging (DTI) provides a unique source of information about the underlying tissue structure of brain white matter in vivo including both the geometry of major fiber bundles as well as quantitative information about tissue properties represented by derived tensor measures. This paper...Diffusion tensor imaging; Registration; Tract modeling; Neurodevelopment; Statistical modeling2009-01-01
5 Gerig, GuidoNeuroimaging of structural pathology and connectomics in traumatic brain injury: toward personalized outcome predictionRecent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view that multimodal neuroimaging using structural and functionalmagnetic resonance imaging (MRI and fMRI, respectively) as well as diffusion tensor imaging (DTI) has excellent potential to identify novel biomark...Trauma; Neuroimaging; MRI/fMRI; Diffusion tensor; Outcome measures2012-01-01
6 Gerig, GuidoObject models in multiscale intrinsic coordinates via m-repsObject descriptions used for 3D segmentation by deformable models and for statistical characterization of 3D object classes benefit from having intrinsic correspondences over deformation of the objects or multiple instances in the same object class. These correspondences apply over a variety of spat...2003-01-01
7 Gerig, GuidoPrenatal isolated mild ventriculomegaly is associated with persistent ventricle enlargement at ages 1 and 2Background-Enlargement of the lateral ventricles is thought to originate from abnormal prenatal brain development and is associated with neurodevelopmental disorders. Fetal isolated mild ventriculomegaly (MVM) is associated with enlargement of lateral ventricle volumes in the neonatal period and dev...Magnetic resonance imaging; Ultrasound; Gray matter; White matter; Cognitive development2012-01-01
8 Gerig, GuidoProbabilistic white matter fiber tracking using, particle filtering and von mises-fisher samplingStandard particle filtering technique have previously been applied to the problem of fiber tracking by Brun et al. (2002) and Bjornemo et al. (2002). However, these previous attempts have not utilised the full power of the technique, and as a result the fiber paths were tracked in a goal directed wa...Diffusion tensor MRI; Tractography; Probabilistic fiber tracking; Particle filtering; von Mises-Fisher sampling2009-01-01
9 Gerig, GuidoQuantitative tract-based white matter development from birth to age 2 yearsFew large-scale studies have been done to characterize the normal human brain white matter growth in the first years of life. We investigated white matter maturation patterns in major fiber pathways in a large cohort of healthy young children from birth to age two using diffusion parameters fraction...White matter maturation; Axonal myelination; Early brain development; Diffusion properties; DTI atlas; Fiber tracking; Functional regression analysis2012-01-01
10 Gerig, GuidoReduced interhemispheric connectivity in schizophrenia- tractography based segmentation of the corpus callosumBackground-A reduction in interhemispheric connectivity is thought to contribute to the etiology of schizophrenia. Diffusion Tensor Imaging (DTI) measures the diffusion of water and can be used to describe the integrity of the corpus callosum white matter tracts, thereby providing information concer...2008-01-01
11 Gerig, GuidoSimulation of brain tumors in MR images for evaluation of segmentation efficacy.Obtaining validation data and comparison metrics for segmentation of magnetic resonance images (MRI) are difficult tasks due to the lack of reliable ground truth. This problem is even more evident for images presenting pathology, which can both alter tissue appearance through infiltration and cause ...Brain MRI; Segmentation validation; Tumor simulation; Simulation of tumor infiltration; Diffusion tensor imaging; Ground truth; Gold standard2009-01-01
12 Gerig, GuidoUser-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliabilityActive contour segmentation and its robust implementation using level set methods are well-established theoretical approaches that have been studied thoroughly in the image analysis literature. Despite the existence of these powerful segmentation methods, the needs of clinical research continue to b...Computational anatomy; Image segmentation; Caudate nucleus; 3D active contour models; Open source software; Validation; Anatomical objects2006-01-01
13 Gerig, GuidoVessel tortuosity and brain tumor malignancy: a blinded studyRationale-Malignancy provokes regional changes to vessel shape. Characteristic vessel tortuosity abnormalities appear early during tumor development, affect initially healthy vessels, spread beyond the confines of tumor margins, and do not simply mirror tissue perfusion. The ability to detect and qu...Computer; Cancer; Blood vessels; Tortuosity; MRA; Brain tumor2005-01-01
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