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1 Olivera, Baldomero M.; McIntosh, J. Michael; Gray, William Robertγ-Carboxyglutamate in a neuroactive toxinThe venom of a fish-hunting cone snail (Conus geographus) contains a novel toxin, the "sleeper" peptide, which induces a sleep-like state in mice when injected intracerebrally. We demonstrate that this peptide contains 5 mol of γ-carboxyglutamate (Gla) in 17 amino acids. The amino acid sequence o...Conus geographus; Venom; Conotoxins; gamma-Carboxyglutamate; Neurotoxins1984
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