Creator | Title | Description | Subject | Date | ||
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1 |
![]() | Olivera, Baldomero M. | Poly(ADP-ribosylation) of a DNA topoisomerase | A DNA topoisomerase activity, copurifying with poly(ADP-ribose) synthetase from calf thymus, >95% inhibited if extensive poly(ADP-ribosylation) is allowed to occur. The inhibited DNA topoisomerase, which has drastically different elution properties on hydroxylapatite, can be reactivated by mild alka... | Nicotinic acid; ADP-ribosylation; Turnover cycle; Synthetases | 1983 |
2 |
![]() | Olivera, Baldomero M.; Hillyard, David R. | Pyridine nucleotide cycle: studies in Escherichia coli and the human cell line D98/AH2 | Different metabolic steps comprise the pyridine nucleotide cycles in Escherichia coli and in the human cell line HeLa D98/AH2. An analysis of the "P-labeling patterns in vivo reveals that in E. coli, pyrophosphate bond cleavage of intracellular NAD predominates, while in the human cell line, cleava... | Nicotinic acid; Turnover cycle; DNA ligation; Nicotinamide | 1981 |
3 |
![]() | Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. IV. Turnover | There are two pyridine nucleotide turnover pathways in Escherichia coli, the Gholson turnover cycle, with nicotinamide as an intermediate, and a second new pathway which does not involve nicotinamide. In exponentially growing cultures with a generation time of 60 min, the rates of these cycles are ... | Turnover cycle; Adenine | 1973 |