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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Olivera, Baldomero M.; McIntosh, J. Michael; Gray, William Robert; Hillyard, David R. | New family of conotoxins that block voltage-gated sodium channels | Conus peptides, including ω-conotoxins and α-conotoxins (targeting calcium channels and nicotinic acetylcholine receptors, respectively) have been useful ligands in neuroscience. In this report, we describe a new family of sodium channel ligands, the μO-conotoxins. | Conotoxins; Sodium channel blockers | 1995 |
| 2 |
 | Olivera, Baldomero M.; Zhang, MinMin; Azam, Layla; Yoshikami, Doju; Bulaj, Grzegorz | Structure/function characterization of μ-Conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels | Peptide neurotoxins from cone snails continue to supply compounds with therapeutic potential. Although several analgesic conotoxins have already reached human clinical trials, a continuing need exists for the discovery and development of novel nonopioid analgesics, such as subtype-selective sodium c... | Conotoxins; 956;-Conotoxin KIIIA; Neuronal blocker; Neurotoxins; Sodium channel blockers | 2007 |
| 3 |
 | Olivera, Baldomero M.; Gray, William Robert; Hillyard, David R. | μ-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes | We report the characterization of a new sodium channel blocker, m-conotoxin PIIIA (m-PIIIA). The peptide has been synthesized chemically and its disulfide bridging pattern determined. | Conotoxins; m-Conotoxin PIIIA; Sodium channel blockers | 1998 |
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