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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Gesteland, Raymond F.; Weiss, Robert B. | Efficient shine- Dalgarno sequence but not translation is necessary for LacZ mRNA stability in Escherichia coli | The 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation c... | Protein Biosynthesis; Ribosomes; Escherichia coli; Shine-Dalgarno Sequence | 1994 |
| 2 |
 | Capecchi, Mario R. | Measurement of suppressor transfer RNA activity. | Transfer RNA (tRNA) suppression of nonsense mutations in prokaryotic systems has been widely used to study the structure and function of different prokaryotic genes. Through genetic engineering techniques, it is now possible to introduce suppressor (Su+) tRNA molecules into mammalian cells. A quanti... | Animals; Cells, Cultured; Eukaryotic Cells; Genes, Viral; Mice; Orthomyxoviridae; Peptide Chain Termination, Translational; Protein Biosynthesis | 1983-08-26 |
| 3 |
 | Gesteland, Raymond F.; Atkins, John F. | Origin and destiny of adenovirus proteins | Lytic infection of human cells by adenovirus proceeds by a temporal expression of genes. Classically two phases have been defined: an early phase, which includes events occurring before the onset of DNA synthesis (8 hours), and a late phase, including events whose existence depends on the onset of... | Protein Biosynthesis; DNA, Viral; Adenoviridae; RNA, Viral; Time Factors | 1975 |
| 4 |
 | Gesteland, Raymond F.; Atkins, John F.; Tuohy, Therese M. | Uninterrupted translation through putative 12-nucleotide coding gap in sequence of carA: business as usual | Previous work of others reported an untranslated stretch of 12 nucleotides in the 5' coding sequence of carA from Pseudomonas aeruginosa. However, N-terminal protein sequencing of carA-lacZ translational fusions shows that these 12 nucleotides are normally translated in a continuous triplet manner, ... | Base Sequence; Protein Biosynthesis; Sequence Deletion | 1994 |
| 5 |
 | Capecchi, Mario R. | Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. | tRNA isolated from two different yeast super-suppressor strains translates a known nonsense mutation in vitro, whereas tRNA from a closely related nonsuppressing strain does not. Suppression was assayed by translation of RNA isolated from an amber coat mutant of bacteriophage Qbeta (GB11) in a prote... | Codon; Escherichia coli; Protein Biosynthesis | 1975-11 |
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