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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Olivera, Baldomero M. | Poly (ADP-ribosylation) in Vitro: reaction parameters and enzyme mechanism | The reaction catalyzed by poly(ADP-ribose) synthetase from bovine thymus was investigated using the purified enzyme, calf thymus DNA, and histone H1. The rate and extent of poly(ADP-ribosylation), as well as the spectrum of acceptor proteins, changed as reaction conditions were varied. The ionic co... | ADP-ribosylation; Poly(ADP-ribose) synthetase; Histone H1 | 1982 |
| 2 |
 | Olivera, Baldomero M. | Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus | We demonstrate that the activity of the major DNA topoisomerase I from calf thymus is severely inhibited after modification by purified poly(ADP-ribose) synthetase. Polymeric chains of poly(ADP-ribose) are covalently attached to DNA topoisomerase I. These observations with highly purified enzymes ... | ADP-ribosylation; Poly(ADP-ribose) synthetase | 1984 |
| 3 |
 | Olivera, Baldomero M. | Poly(ADP-ribosylation) of DNA topoisomerase I: a nuclear response to DNA-strand interruptions | DNA in eukaryotic chromosomes is organized differently from prokaryotic DNA. It seems highly probable that mechanistic adjustments have been made in macromolecular DNA metabolism as a consequence of the chromatin structure of the eukaryotic chromosome (Igo-Kemenes et al. 1982)). This paper deals ... | Poly(ADP-ribosylation); Poly(ADP-ribose) synthetase; DNA strand interruption | 1984 |
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