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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael | Differential targeting of nicotinic acetylcholine receptors by novel αA-conotoxins | We describe the isolation and characterization of two peptide toxins from Conus ermineus venom targeted to nicotinic acetylcholine receptors (nAChRs). The peptide structures have been confirmed by mass spectrometry and chemical synthesis. In contrast to the 12-18 residue, 4 Cys-containing α-co... | Conotoxins; aA-conotoxins; Conus ermineus; Peptide toxins | 1997 |
| 2 |
 | Olivera, Baldomero M. | Identification of a novel pharmacophore for peptide toxins interacting with K+ channels | қM-conotoxin RIIIK blocks TSha1 K+ channels from trout with high affinity by interacting with the ion channel pore. As opposed to many other peptides targeting K+ channels, қM-RIIIK does not possess a functional dyad. In this study we combine thermodynamic mutant cycle analysis and docking calc... | Conotoxins; Peptide toxins; қM-conotoxin RIIIK; Pharmacophore | 2005 |
| 3 |
 | Olivera, Baldomero M.; ; McIntosh, J. Michael | Localization of [125I] ω-conotoxin GVIA binding in human hippocampus and cerebellum | THE peptide toxin ω-conotoxin GVIA (ω-CgTx) has been shown to be a high affinity ligand for N-type calcium channels in the brain. We have employed [125I]ω-CgTx to localize N-type channels in human hippocampus and cerebellum using autoradiography. Ten micron thick slidemounted tissue sections of... | Conotoxins; Peptide toxins | 1993 |
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