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CreatorTitleDescriptionSubjectDate
1 Christensen, Douglas A.Planar waveguide biosensors for nucleic acid hybridization reactionsOligonucleotide probes derived from (1) the T3 RNA polymerase promoter sequence (T3) and (2) prostate-specific antigen messenger RNA (PSA) were prepared and labeled with a red-emitting fluorescent dye (Cy5). The complimentary oligonucleotides (anti T3 and anti PSA) were prepared and labeled with bio...Planar waveguides; Evanescence; Fluorescence; Glandular kallikrein; MDx; Molecular diagnostics; Nucleic acid; PSA; Oligonucleotide probes2000
2 Christensen, Douglas A.; Herron, James N.Rapid single nucleotide polymorphism detection for personalized medicine applications using planar waveguide fluorescence sensorsPersonalized medicine is an emerging field in which clinical diagnostics information about a patient's genotype or phenotype is used to optimize his/her pharmacotherapy. This article evaluates whether planar waveguide fluorescent sensors are suitable for determining such information from patient tes...Personalized medicine; Planar waveguides; Fluorescence sensors; Evanescent excitation; Fluorescence; Hybridization; Molecular diagnostics; Peptide nucleic acid; Point of care; Single base extension; Single nucleotide polymorphism2006
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