Creator | Title | Description | Subject | Date | ||
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1 |
![]() | Camp, Nicola J. | Genome-wide linkage analysis for aggressive prostate cancer in Utah high risk pedigrees | Research has consistently shown that genetics plays a critical role in prostate cancer (CaP) development, but the identification of CaP genes has proven to be very difficult. Hereditary prostate cancer is a complex disease involving numerous genes and variable phenotypic expression. This heterogene... | Linkage analysis; Aggressive prostate cancer; CaP genes; ICPCG; Utah; Trapeze Interactive Poster | 2009 |
2 |
![]() | Camp, Nicola J. | SumLINK statistic for linkage analysis: application to the ICPCG pooled linkage resource | We propose a novel, genome-wide, linkagebased statistic, "sumLINK," for identification of disease susceptibility loci. Our approach focuses primarily on "linked" pedigrees (those with pedigree-specific LOD ? 0.588; equivalent to unadjusted p ? 0.05) to identify regions of extreme consistency across ... | SumLINK; Linkage analysis; ICPCG; Disease susceptibility loci; Trapeze Interactive Poster | 2009 |