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| Creator | Title | Description | Subject | Date | ||
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 | Capecchi, Mario R. | Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. | Mutations were targeted to the Hprt locus of mouse embryo-derived stem cells by using 22 different sequence replacement and sequence insertion vectors. The targeting frequency was examined at two sites within the Hprt locus as a function of the extent of homology between the targeting vector and the... | Cell Line; DNA Transposable Elements; Embryo; Exons; Mice | 1992-08-12 |
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