UScholar Works
 
Filters: Format: "application/pdf" Collection: "ir_uspace" Subject: "Conus geographus"
1 - 25 of 6
Number of results to display per page
CreatorTitleDescriptionSubjectDate
1 Olivera, Baldomero M.Biochemical studies of ω-conotoxin GVIA; a peptide toxin inhibiting voltage-sensitive Ca++ channelsThe fish-hunting cone snails use their venom to quickly paralyze their more agile prey. In the last few years, our laboratories have carried out a program of analyzing biologically active components present in the fish-hunting cone snail venoms (Cruz et al. 1985; Olivera et al. 1985). We have concen...Conotoxins; Calcium channels; Conus geographus; Venom1987
2 Olivera, Baldomero M.; Gray, William Robert; Yoshikami, DojuConus geographus toxins that discriminate between neuronal and muscle sodium channelsWe describe the properties of a family of 22-amino acid peptides, the μ-conotoxins, which are useful probes for investigating voltage-dependent sodium channels of excitable tissues. The μ-conotoxins are present in the venom of the piscivorous marine snail, Conus geographus L. We have purified even...Conus geographus; Venom; Conotoxins; Sodium channels; Neurotoxins1985
3 Olivera, Baldomero M.; Gray, William RobertInvertebrate vasopressin/oxytocin homologs: characterization of peptides from Conus geographus and Conus striatus venomsThe vasopressin-oxytocin family of peptides is of very ancient lineage, found in organisms as diverse as hydra and man. Although these peptides have been intensively studied in vertebrates, the presumably more extensive invertebrate series was defined primarily by immunological methods. In this repo...Conus geographus; Conus striatus; Venom; Conotoxins; Neurotoxins; Postsynaptic inhibition; Vasopressin-oxytocin peptides; Conopressin1987
4 Olivera, Baldomero M.; Gray, William RobertPeptide toxins from Conus geographus venomThe biochemical characterization of three highly toxic peptides from the venom of the marine snail Conus geographus is described in this report. These peptides cause their potent activity by inhibition of the postsynaptic terminus of the vertebrate neuromuscular junction. The relatively small size o...Conus geographus; Venom; Conotoxins; Neurotoxins1981
5 Olivera, Baldomero M.; McIntosh, J. Michael; Yoshikami, Dojuα-Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptorsMany venomous organisms produce toxins that disrupt neuromuscular communication to paralyze their prey. One common class of such toxins comprises nicotinic acetylcholine receptor antagonists (nAChRs). Thus, most toxins that act on nAChRs are targeted to the neuromuscular subtype. The toxin chara...Conotoxins; Conotoxin GIC; Conus geographus; Peptide antagonists2002
6 Olivera, Baldomero M.; McIntosh, J. Michael; Gray, William Robertγ-Carboxyglutamate in a neuroactive toxinThe venom of a fish-hunting cone snail (Conus geographus) contains a novel toxin, the "sleeper" peptide, which induces a sleep-like state in mice when injected intracerebrally. We demonstrate that this peptide contains 5 mol of γ-carboxyglutamate (Gla) in 17 amino acids. The amino acid sequence o...Conus geographus; Venom; Conotoxins; gamma-Carboxyglutamate; Neurotoxins1984
1 - 25 of 6