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 | Olivera, Baldomero M.; Zhang, MinMin; Azam, Layla; Yoshikami, Doju; Bulaj, Grzegorz | Structure/function characterization of μ-Conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels | Peptide neurotoxins from cone snails continue to supply compounds with therapeutic potential. Although several analgesic conotoxins have already reached human clinical trials, a continuing need exists for the discovery and development of novel nonopioid analgesics, such as subtype-selective sodium c... | Conotoxins; 956;-Conotoxin KIIIA; Neuronal blocker; Neurotoxins; Sodium channel blockers | 2007 |