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Filters: Format Medium: "application/pdf" Collection: "ir_uspace" Subject: "Mouse embryo-derived stem cells"
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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Capecchi, Mario R.; Thomas, Kirk R. | Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells | We mutated, by gene targeting, the endogenous hypoxanthine phosphorlbosyl transferase (HPFlT) gene in mouse embryo-derived stem (ES) cells. A specialized construct of the neomycin resistance (NO') gene was introduced into an exon of a cloned fragment of the Hprf gene and used to transfect ES cell... | Site-directed mutagenesis; Hypoxanthine phosphorlbosyl transferase gene; HPFlT gene; Neomycin resistance gene; Homologous recombination; Mouse stem cells; Mouse embryo-derived stem cells | 1987 |
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