TO
1 - 25 of 3
| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Christensen, Douglas A.; Herron, James N. | Optical immunoassay systems based upon evanescent wave interactions | Immunoassays based upon evanescent wave interactions are finding increased biosensing application. In these devices, the evanescent tail associated with total internal reflection of an incident beam at the substrate/solution interface provides sensitivity for surface-bound proteins over bulk molec... | Diagnostics; Evanescence; Planar waveguides; Human chorionic gonadotropin (hCG) | 1996 |
| 2 |
 | Christensen, Douglas A. | Planar waveguide biosensors for nucleic acid hybridization reactions | Oligonucleotide probes derived from (1) the T3 RNA polymerase promoter sequence (T3) and (2) prostate-specific antigen messenger RNA (PSA) were prepared and labeled with a red-emitting fluorescent dye (Cy5). The complimentary oligonucleotides (anti T3 and anti PSA) were prepared and labeled with bio... | Planar waveguides; Evanescence; Fluorescence; Glandular kallikrein; MDx; Molecular diagnostics; Nucleic acid; PSA; Oligonucleotide probes | 2000 |
| 3 |
 | Christensen, Douglas A.; Herron, James N. | Rapid clinical diagnostics assays using injection-molded planar waveguides | The goal of our research program is to develop an evanescent wave immunoassay system that can be used in point-of-care and critical care settings. Several key attributes are required to accomplish this goal: (i) the assay system should be at least as sensitive as present day immunoassays; (ii) assay... | Planar waveguides; Creatine phosphokinase MB (CK-MB); Cardiac troponin I (cTnl); Diagnostics; Evanescence; Fluorescence; Human chorionic gonadotropin (hCG) | 1998 |
1 - 25 of 3