|
|
Creator | Title | Description | Subject | Date |
| 1 |
 |
Digre, Kathleen B.; Gouw, Launce G.; Harris, Catherine P.; Haines, John H.; Ptacek, L.J. | Autosomal dominant cerebellar ataxia with retinal degeneration: clinical, neuropathologic, and genetic analysis of a large kindred. | The autosomal dominant cerebellar ataxias (ADCA) comprise a heterogeneous group of neurologic disorders characterized by degeneration of the cerebellum, spinal cord, and brainstem. Genetic analysis has revealed two loci, SCA1 on chromosome 6p, and SCA2 on chromosome 12q, responsible for some ADCA. W... | Retinal Degeneration; Cerebellar Ataxia; Genetic Analysis | 1994-08 |
| 2 |
 |
Jaskowski, Troy D. | Diagnostic performance of phospholipid-specific assays for the evaluation of antiphospholipid syndrome | The diagnostic performance of commercially available nonstandard antiphospholipid (aPL) assays for the evaluation of antiphospholipid syndrome (APS) is unknown. In 62 patients with APS, 88 with recurrent pregnancy loss, 50 healthy blood donors, and 24 women with one or more successful pregnancies, w... | APS; Phospholipid-specific assays; Diagnostic performance | 2008-06-01 |
| 3 |
 |
Hymas, Weston C.; Hillyard, David R. | Novel one step real time RT-PCR assay for the detection of Enterovirus, A | This poster describes the development of a novel real time assay that utilizes primers and an Eclipse probe in an overlapping format upstream of the Rotbart amplicon. | RT-PCR Assay | 2005-11-08 |
| 4 |
 |
Liew, Michael; Erali, Maria; Page, Sam; Hillyard, David R.; Wittwer, Carl T. | Hepatitis C genotyping by denaturing high-performance liquid chromatography | Determination of the hepatitis C virus (HCV) genotype for infected patients increasingly has become accepted as the standard of care. Genotype assignment helps in assessing disease prognosis and assists in establishing the appropriate duration of treatment. The great genetic diversity of HCV, with 1... | Base Sequence; 5' Untranslated Regions; Genotype; Hepacivirus; Molecular Sequence Data | 2004-01 |
| 5 |
 |
Owen, William E.; Roberts, William L. | Comparison of five automated serum and whole blood folate assays | Serum and whole blood folate measurements are used to establish folate deficiency. Most methods used in clinical laboratories are automated, nonisotopic methods that use folate-binding protein. Linearity, imprecision, and method comparison studies, including serum and whole blood hemolysates, wer... | Folate assays; Serum folate; Whole blood folate; Automated assays | 2003 |
| 6 |
 |
Erickson, J. Alan; Ashwood, Edward R. | Evaluation of an enzyme-linked binding protein assay for hyaluronic acid and concentrations in hepatitis C infected patients | Serological hyaluronic acid (HA) has been proposed as a noninvasive alternative to liver biopsy for assessing the extent of liver fibrosis. Liver biopsy correctly identifies hepatic disease in about 65 to 75% of cases, being strongly dependent on the length of the biopsy obtained. Furthermore, hepat... | Hyaluronic Acid Concentration; Corgenix HA assay | 2005-07-21 |
| 7 |
 |
Litwin, Christine M. | Anti-tuberculosis IgG antibodies as a marker of active mycobacterium tuberculosis disease | Anti-Mycobacterium tuberculosis IgG antibodies may aid in the diagnosis of active M. tuberculosis disease. We studied whether anti-M. tuberculosis IgG antibodies are elevated in active M. tuberculosis disease and assessed factors contributing to false positive and negative results. A retrospective s... | | 2012-01-01 |
| 8 |
 |
Owen, William E.; Roberts, William L. | Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods. | Glycohemoglobin (GHB), reported as hemoglobin (Hb) A1c, is a marker of long-term glycemic control in patients with diabetes and is directly related to risk for diabetic complications. HbE and HbDare the second and fourth most common Hb variants worldwide. We investigated the accuracy of HbA1c measur... | Glycohemoglobin; GHB; Glycated Hb; Glycemic control | 2008 |
| 9 |
 |
Roberts, William L. | Specificity characteristics of 7 commercial creatinine measurement procedures by enzymatic and jaffe method principles | Standardized calibration does not change a creatinine measurement procedure?s susceptibility to potentially interfering substances. | | 2012 |
| 10 |
 |
Kriesel, John D.; Baringer, J R; Spruance, Spotswood L. | Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation-induced herpes labialis. | We examined the oral secretions of 25 patients for herpes simplex virus (HSV) at the time of and following experimental UV radiation (UVR). HSV was detected in one or more oral secretion specimens in 5 of 12 (42%) cases by cell culture and in 8 of 12 (67%) cases by PCR. On the day of UVR, HSV was de... | Polymerase Chain Reaction; Ultraviolet Rays; Simplexvirus | 1994 |
| 11 |
 |
Hymas, Weston C.; Hillyard, David R. | Description and validation of a novel real-time RT-PCR enterovirus assay | Enteroviruses are a leading cause of aseptic meningitis in adult and pediatric populations. We describe the development of a real-time RT-PCR assay that amplifies a small target in the 5' nontranslated region upstream of the classical Rotbart enterovirus amplicon. The assay includes an RNA internal ... | RT-PCR enterovirus assay; Rotbart enterovirus amplicon; Aseptic meningitis | 2008 |
| 12 |
 |
Rockwood, Alan L. | Mass spectrometry for steroids, immunosuppressants, and other clinical applications | Presentation slides on matching mass spectrometry technology to clinical applications. | Immunosuppressants | 2005-07-26 |
| 13 |
 |
Owen, William E.; Roberts, William L. | Comparable effects of DIGIBIND and DigiFab in thirteen digoxin immunoassays | Digoxin is widely prescribed for the treatment of cardiac conditions (1). Because of its narrow therapeutic range, digoxin-related toxicity resulting from acute or chronic overdose is common. Metabolites of digoxin as well as related compounds, including digitoxin, tanshinones, bufandienolide, a... | DIGIBIND; DigiFab; Digoxin immunoassays; Digoxin toxicity | 2002 |
| 14 |
 |
Dwight, Zachary Lawrence | Heterozygote PCR product melting curve prediction | Melting curve prediction of PCR products is limited to perfectly complementary strands. Multiple domains are calculated by recursive nearest-neighbor thermodynamics. However, the melting curve of an amplicon containing a heterozygous single nucleotide variant (SNV) after PCR is the composite of four... | | 2014-01-01 |
| 15 |
 |
Erickson, J. Alan; Smith, Jeffrey, J.; Bornhorst, Joshua A.; Ashwood, Edward R. | Humananti-mouse antibody protected ELISA for the quantification of squamous cell carcinoma antigen | Squamous cell carcinoma antigen (SCC) was first isolated from squamous cell carcinoma tissue of the uterine cervix and initially reported as TA-4. The antigen has been characterized as a glycoprotein with a molecular weight between 45,000 and 55,000 daltons. Studies suggest that SCC may function as ... | SCC; Squamous Cell Carcinoma Antigen; BSA; PBS; Phosphate Buffered Saline; HAMA; Human Anti-mouse Antibodies; IIR; ImmunoglobulinInhibiting Reagent | 2005-12-09 |
| 16 |
 |
Rockwood, Alan L. | Performance enhancement in the measurement of 5 endogenous steroids by LC-MS/MS combined with differential ion mobility spectrometry | Background: Challenges for steroid analysis by LC-MS/MS include low ionization efficiency, endogenous isobars with similar fragmentation patterns and chromatographic retention. Differential ion mobility spectrometry (DMS) provides an additional degree of separation prior to MS/MS detection, and show... | | 2014-01-01 |
| 17 |
 |
Petti, Cathy A. | Role of the laboratory in diagnosis of influenza during seasonal epidemics and potential pandemics | Laboratory diagnosis of influenza is critical to its treatment and surveillance. With the emergence of novel and highly pathogenic avian influenza viruses, the role of the laboratory has been further extended to include isolation and subtyping of the virus to monitor its appearance and facilitate ap... | Antibodies, Viral; Antigens, Viral; RNA, Viral | 2006 |
| 18 |
 |
Jaskowski, Troy D. | Comparison of capillary zone and immunosubtraction with agarose gel and immunofixation electrophoresis for detecting and identifying monoclonal gammopathies | Capillary zone electrophoresis (CZE) and immunosubtraction electrophoresis (ISE) were evaluated for ability to detect and immunotype monoclonal proteins, compared with agarose gel electrophoresis (AGE) and immunofixation electrophoresis (IFE), respectively. Six hundred seventeen serum samples wer... | Capillary zone electrophoresis; Immunosubtraction electrophoresis; CZE; ISE; Monoclonal protein electrophoresis; Serum protoin electrophoresis; Agarose gel; Dysproteinemias | 1999 |
| 19 |
 |
Smith, A. Gordon; Singleton, J. Robinson | Lifestyle intervention for pre-diabetic neuropathy. | OBJECTIVE: The purpose of this study was to evaluate intraepidermal nerve fiber density (IENFD) as a sensitive measure of neuropathy change in patients with neuropathy associated with impaired glucose tolerance (IGT) receiving lifestyle intervention based on that used in the Diabetes Prevention Prog... | Older people; Biopsy; Blood Pressure; Body Mass Index; Cholesterol; Diabetic Diet | 2006-06-29 |
| 20 |
 |
Kriesel, John D.; Spruance, Spotswood L.; Daynes, Raymond A. | Nucleic acid vaccine encoding gD2 protects mice from herpes simplex virus type 2 disease. | Nucleic acid vaccinations with plasmids pWW65, containing the sequence for herpes simplex type 2 (HSV-2) gD2, and pRSVnt, lacking the gD sequence, were studied. Groups of mice were immunized with pWW65 alone, pWW65 plus 1,25-dihydroxyvitamin-D3 (D3), or pRSVnt. Clinical disease (vaginitis), serum an... | Mice, Inbred BALB C; Plasmids; Viral Vaccines | 1996 |
| 21 |
 |
Cloud, Joann L.; Dunn, Jim; Hoggan, Karen; Wilson, Deborah; Iwen, Peter; Lasala, Paul; Hall, Geri; Woods, Gail L. | Sequence-based identification of gram negative nonfermenters using commercial 16S rDNA databases | This poster presents a study assessing the validity of the databases from two commercial systems were compared for the identification of NF. Background: Identification of gram negative nonfermenters (NF) from cultured human specimens is often difficult using traditional phenotypic methods. Partial 1... | MicroSeq500; Virodec | 2005-08-29 |
| 22 |
 |
Dwight, Zachary Lawrence | uAnalyze: web-based high-resolution DNA melting analysis with comparison to thermodynamic predictions | Abstract-uAnalyzeSM is a web-based tool for analyzing high-resolution melting data of PCR products. PCR product sequence is input by the user and recursive nearest neighbor thermodynamic calculations used to predict a melting curve similar to uMELT (http://www.dna.utah.edu/umelt/umelt.html). Unproce... | | 2012-01-01 |
| 23 |
 |
Coffin, Cheryl M.; Capecchi, Mario R. | Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. | Alveolar rhabdomyosarcoma is an aggressive childhood muscle cancer for which outcomes are poor when the disease is advanced. Although well-developed mouse models exist for embryonal and pleomorphic rhabdomyosarcomas, neither a spontaneous nor a transgenic mouse model of alveolar rhabdomyosarcoma has... | Cell Differentiation; Forkhead Transcription Factors; Myogenic Regulatory Factors | 2004-11-01 |
| 24 |
 |
Erickson, J. Alan; Aldeen, William E.; Ashwood, Edward R. | Evaluation of a fecal pancreatic elastase-1 enzyme-linked immunosorbent assay: assessment versus an established assay and implication in classifying pancreatic function | Disagreement continues regarding the two commercially available fecal pancreatic elastase-1 (PE-1) ELISAs and their respective capabilities to assess pancreatic function. Our objectives were to validate the newer PE-1 ELISA and evaluate the test against the previously established assay, to investiga... | PE-1; pancreatic elastase-1; FDA; AMR; analytical measurement range; BioServ Diagnostics PE-1ELISA; ScheBo Biotech PE-1ELISA | 2005-09-25 |
| 25 |
 |
Cloud, Joann L.; Meyer, Jay J.; Pounder, June I.; Woods, Gail L. | Mycobacterium arupense sp. nov., a novel moderately growing nonchromogenic bacterium isolated from clinical specimens | This author manuscript discusses how several isolates of Mycobacterium species related to the M. terrae complex have been isolated from clinical samples. In the clinical microbiology laboratory, partial 16S rRNA gene sequencing (approximate first 500 base pairs) is often used to identify Mycobacteri... | Mycobacterium arupense; Mycobacterium nonchromogenicum; Mycobacterium terrae; Mycobacterium triviale; MCRO 6 | 2005-11-22 |
