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Creator | Title | Description | Subject | Date |
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Baehr, Wolfgang | Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel | We have determined the primary structures of the human and mouse retinal rod cGMP-gated cation channel by analysis of cDNA clones and amplified DNA. The open reading frames predicted polypeptides of 690 and 683 residues exhibiting 88% sequence similarity. Sequence comparison indicated that the rod c... | Restriction Mapping; Sequence Homology, Nucleic Acid; Chromosomes, Human, Pair 4 | 1992 |
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Baehr, Wolfgang | Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene | Guanylate cyclase-activating protein (GCAP) is a novel Ca(2+)-binding protein that stimulates synthesis of cGMP in photoreceptors. Molecular cloning of human and mouse GCAP cDNA revealed that the known mammalian GCAPs are more than 90% similar, consist of 201-205 amino acids, and contain three ident... | Amino Acid Sequence; Base Sequence; Cloning, Molecular | 1994 |
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Baehr, Wolfgang | Mouse opsin. Gene structure and molecular basis of multiple transcripts | The single copy mouse opsin gene produces five major transcripts, varying in size from 1.7 to 5.1 kilobases. The mRNAs are present at levels that vary over 2 orders of magnitude and can be detected as early as postnatal day 1. Each of the transcripts is polyadenylated and can be identified in polyso... | Polyribosomes; Restriction Mapping; Sequence Homology, Nucleic Acid | 1990 |