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1 Baehr, WolfgangPrimary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channelWe have determined the primary structures of the human and mouse retinal rod cGMP-gated cation channel by analysis of cDNA clones and amplified DNA. The open reading frames predicted polypeptides of 690 and 683 residues exhibiting 88% sequence similarity. Sequence comparison indicated that the rod c...Restriction Mapping; Sequence Homology, Nucleic Acid; Chromosomes, Human, Pair 41992
2 Baehr, WolfgangMolecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human geneGuanylate cyclase-activating protein (GCAP) is a novel Ca(2+)-binding protein that stimulates synthesis of cGMP in photoreceptors. Molecular cloning of human and mouse GCAP cDNA revealed that the known mammalian GCAPs are more than 90% similar, consist of 201-205 amino acids, and contain three ident...Amino Acid Sequence; Base Sequence; Cloning, Molecular1994
3 Baehr, WolfgangMouse opsin. Gene structure and molecular basis of multiple transcriptsThe single copy mouse opsin gene produces five major transcripts, varying in size from 1.7 to 5.1 kilobases. The mRNAs are present at levels that vary over 2 orders of magnitude and can be detected as early as postnatal day 1. Each of the transcripts is polyadenylated and can be identified in polyso...Polyribosomes; Restriction Mapping; Sequence Homology, Nucleic Acid1990
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