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| Creator | Title | Description | Subject | Date | ||
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Capecchi, Mario R. | Lessons from angiotensin-converting enzyme-deficient mice. | Mice which lack ACE have low systolic blood pressure, reduced male fertility and a renal abnormality characterized by medullary hypoplasia and the inability to concentrate urine. The diverse phenotypes caused by inactivation of a single gene emphasize the many functional roles of ACE and the renin-q... | Blood Pressure; Cell Line;Fertility; Kidney; Testis | 1991-11-01 |
| 2 |
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Capecchi, Mario R. | Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. | Mice with targeted disruptions in Hox genes have been generated to evaluate the role of the Hox complex in determining the mammalian body plan. This complex of 38 genes encodes transcription factors that specify regional information along the embryonic axes. Early in vertebrate evolution an ancestra... | Alleles; Animals; Bone and Bones; Carpal Bones | 2003-09-02 |
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