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1 Kestle, John R. W.; Walker, Marion L.Adjustment and malfunction of a programmable valve after exposure to toy magnetsInadvertent adjustments and malfunctions of programmable valves have been reported in cases in which patients have encountered powerful electromagnetic fields such as those involved in magnetic resonance imaging, but the effects of small magnetic fields are not well known. The authors present a ca...2004
2 Dailey, Andrew T.Agreement between orthopedic surgeons and neurosurgeons regarding a new algorithm for the treatment of thoracolumbar injuries: a multicenter reliability studyIntroduction: Considerable variability exists in the management of thoracolumbar (TL) spine injuries. Although there are many influences, one significant factor may be the treating surgeon's specialty and training (ie, orthopedic surgery vs. neurosurgery). Our objective was to assess the agreement ...Thoracolumbar injuries; Rating; Classification; TLISS; Neurosurgery; Interspeciality reliability2006
3 Dailey, Andrew T.; Brodke, Darrel S.; Bachus, Kent N.Anterior cervical fixation: analysis of load-sharing and stability with use of static and dynamic platesBackground: Anterior plates provide stability following decompression and fusion of the cervical spine. Various plate designs have emerged, and they include static plates with fixed-angle screws, rotationally dynamic plates that allow the screws to toggle in the plate, and translationally dynamic pl...Anterior cervical fixation; Load-sharing; Stability; Static plates; Dynamic plates2006
4 Kestle, John R. W.Assessing the validity of the endoscopic shunt insertion trial: did surgical experience affect the results?Object. Most surgical procedures are associated with a learning curve in which the success rate is lower early in the experience before mistakes have been identified and modifications made to the procedure. Negative results obtained early in a trial's learning curve may be a matter of timing rather ...Endoscopic shunt insertion; Ventriculoperitoneal shunt; Pediatric neurosurgery; Surgical experience2004-01-01
5 Couldwell, William T.Assessment of long-term remission of acromegaly following surgeryObject. The criteria for remission of acromegaly following transsphenoidal adenoma resection are in evolution. In the present study the authors evaluate the utility of predicting long-term remission by reference to a single fasting growth hormone (GH) level on the 1st postoperative day. Methods. A ...Acromegaly; Pituitary adenoma; Transsphenoidal surgery; Growth hormone; Insulin-like growth factor I2003-01-01
6 Couldwell, William T.Astrocytoma cell lineTO THE EDITOR: It has long been established clinically that patients with neurofibromatosis Type 1 (NF1) have an increased susceptibility to develop many central and peripheral tumors. The nature of the genetic alterations underlying NF1 have recently begun to be characterized. It has been demo...2001
7 Schmidt, Meic H.; Apfelbaum, Ronald I.Atlantoaxial transarticular screw fixation: a review of surgical indications, fusion rate, complications, and lessons learned in 191 adult patientsObject. In this, the first of two articles regarding C1-2 transarticular screw fixation, the authors assessed the rate of fusion, surgery-related complications, and lessons learned after C1-2 transarticular screw fixation in an adult patient series. Methods. The authors retrospectively reviewed 191 ...Atlantoaxial junction; Craniocervical junction; Instability; Transarticular screw fixation; Fusion2005
8 Schmidt, Meic H.Benzoporphyrin derivative and light-emitting diode for use in photodynamic therapy: applications of space light-emitting diode technologyPhotodynamic therapy (PDT) is a cancer treatment modality that recently has been applied as adjuvant therapy for rain tumors. PDT consists of intravenously injecting a photosensitizer, which preferentially accumulates in tumor ells, into a patient and then activating the photosensitizer with a light...Benzoporphyrin; Photodynamic therapy; Brain tumors; Photofrin1998
9 Couldwell, William T.; Orlandi, Richard R.Carotid artery-sparing repair of a cavernous carotid artery pseudoaneurysmCarotid artery (CA) injury after transsphenoidal and endoscopic sinus surgery is a well-recognized but fortunately rare complication.1 It is associated with significant morbidity and mortality rates5 and is more common in cases of repeated surgery, cavernous sinus invasion, prior radiotherapy, and ...Carotid artery; Sinus; Pseudoaneurysm; Endoscopic surgery2006
10 Gluf, Wayne M.; Gottfried, Oren N.; Schmidt, Meic H.Cavernous hemangioma of the skull presenting with subdural hematomaCavernous hemangioma of the calvarium is a very rare disease, and patients usually present with headaches or a visible skull deformity. Few reports of patients presenting with intradiploic or epidural hemorrhages are found in the literature. No cases of an intradural hemorrhage from a cavernous hema...Hemangioma, Cavernous; Skull; Hematoma, Subdural2004-07-15
11 Schmidt, Meic H.Cavernous hemangioma of the skull presenting with subdural hematomaCavernous hemangioma of the calvaria is a very rare disease, and patients usually present with headaches or a visible skull deformity. Few reports of patients presenting with intradiploic or epidural hemorrhages are found in the literature. No case of an intradural hemorrhage from a cavernous hemang...Calvaria; Cavernous hemangioma2004
12 Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L.Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r...Central Neurogenic H yperventilation; Ocular Motor Dysfunction1990-11
13 Kestle, John R. W.Cerebrospinal fluid shunt technologySince the invention of the first implantable shunt valve by Nulsen and Spitz (12) almost 50 years ago, there has been a remarkable number of ingenious modifications and new designs of shunt equipment to treat pediatric hydrocephalus. These developments were in response to the immediately evident hi...Shunt technology; Valve design2000
14 Schmidt, Meic H.; Apfelbaum, Ronald I.Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resectionObject. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral...Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body2003
15 Schmidt, Meic H.Cervical spine deformity associated with resection of spinal cord tumorsPostoperative sagittal-plane cervical spine deformities are a concern when laminectomy is performed for tumor resection in the spinal cord. These deformities appear to occur more commonly after resection of intramedullary spinal cord lesions, compared with laminectomy for stenosis caused by degener...Kyphosis; Cervical deformity; Intramedullary tumor; Laminectomy; Children2006
16 Kestle, John R. W.Change in ventricular size and effect of ventricular catheter placement in pediatric patients with shunted hydrocephalusOBJECTIVE: The multicenter, randomized pediatric cerebrospinal fluid shunt valve design trial found no difference in the rate of shunt failure between a standard valve, a siphon-reducing valve (Delta; Medtronic PS Medical, Goleta, CA), and a flow-limiting valve (Orbis Sigma; Cordis, Miami, FL); ho...Shunt failure; Valve design; Ventricular size; Ventricular catheter placement1999
17 Couldwell, William T.Cholesteatoma of the clivus case reportObjective: Cholesteatomas (CNS epidermoids) can be found intradurally or extradurally in the central nervous system. Extradural intraosseous lesions are most commonly found in the petrous bone. Design: Case report Clinical Presentation: The authors describe a unique case of a clival cholesteatoma o...2006-01-01
18 Couldwell, William T.Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifenPREVIOUS WORK HAS demonstrated the importance of the Protein Kinase C (PKC) signal transduction system in regulating the growth rate of malignant gliomas in vitro. Tamoxifen inhibits PKC in a minority of malignant gliomas within the micromolar concentration range in vitro, a property distinct from...Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Chemotherapy; Glioma1993
19 Couldwell, William T.Combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumorsCOMPLEX TUMORS OF the glomus jugulare present a surgical challenge because of their difficult location, extreme vascularity, and involvement with multiple cranial nerves. Modern microneurosurgical and cranial base techniques have enabled safe total removal of these complicated tumors. We describe a ...Cranial base approach; Surgical approach; Glomus jugulare tumor; Jugular foramen exposure; Microsurgical anatomy2006
20 Couldwell, William T.Comment on Nugent, G. R.: Targeting the ventral lateral nucleus of the thalamus: a stereotactic vignetteDr. Nugent provides a fascinating personal account of his early experience with stereotactic surgery for movement disorders. I was especially pleased to read the positive comments regarding the personal interactions with and innovations of Irving Cooper, a neurosurgeon who was derided by his peers b...Stereotactic surgery; Stereotaxis2006
21 Couldwell, William T.Comment on Wong, H. T., et al.: Comparative impact of video consultation on emergency neurosurgical referralsThe Author's explored the facility and accuracy of telephone, teleradiology, or video consultation between a large general hospital and their tertiary neurosurgical center. Although there was increased diagnostic accuracy with video consultation or teleradiology, they note that consultation via vid...Teleradiology; Video consultation; Neurosurgical referrals2006
22 Couldwell, William T.Comment on: Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trialsThe long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We report here detection of active brain inflammation 3 months after successful inhibition of syngeneic glioma growth. The inflammatory infiltrate consisted of activated macrophag...Brain inflammation; Herpes simplex virus-1; Thymidine kinase; Syngeneic glioma; Adenovirus-mediated gene therapy1994
23 Couldwell, William T.Communication between malignant glioma cells and vascular endothelial cells through gap junctionsObject. Extensive invasion and angiogenesis are hallmark features of malignant gliomas. Communication between malignant glioma cells and surrounding astrocytes occurs, resulting in transformation of the astrocytic phenotype. In the present study, the authors examined whether malignant glioma cells a...2003-01-01
24 Kestle, John R. W.Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determinationThe spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma...Computed tomography; Stereotactic coordinates; Stereotactic surgery1992
25 Dailey, Andrew T.; Brodke, Darrel S.Comparison of computerized tomography and direct visualization in thoracic pedicle screw placementObject. To validate computerized tomography (CT) scanning as a tool to assess the accuracy of thoracic pedicle screw placement, the authors compared its accuracy with that of direct visualization in instrumented cadaveric spine specimens. Methods. A grading scale was devised to score the placement...Computerized tomography; Direct visualization; Thoracic pedicle screw; Pedicle; Thoracic spine2002
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