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CreatorTitleDescriptionSubjectDate
1 Couldwell, William T.Photophobia in a blind patient: an alternate visual pathwayPhotophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from mult...2006-11
2 Digre, Kathleen B.; Couldwell, William T.; Amini, AminPhotophobia in a blind patient: An alternate visual pathway. Case report.Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from multi...Photophobia, Blindness, Signaling Pathway, Pretectal Nuclei, Trigeminal Pathway2006-12-14
3 Digre, Kathleen B.; Skuster, Denise Z.Neurologic conditions presenting as psychiatric disorders.Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit...Psychiatric Diagnosis; Neurologic Disease1992-06-15
4 Kestle, John R. W.; Brockmeyer, Douglas LeeOptic pathway gliomas: a reviewOptic pathway gliomas represent approximately 3-5% of childhood intracranial tumors. They usually occur in children during the first decade of life and are seen in 11-30% of patients with neurofibromatosis Type 1 (NF1). Although these tumors are typically low-grade gliomas, the clinical course and n...Optic pathway glioma; Hypothalamus glioma; Neurofibromatosis Type 12007
5 Schmidt, Meic H.Is vertebral augmentation the right choice for cancer patients with painful vertebral compression fractures?Cancer-related fractures of the spine are different from osteoporotic ones, not only in pathogenesis but also in natural history and treatment. Higher class evidence now supports offering balloon kyphoplasty to a patient with cancer, provided that the pain is significant in intensity, has a position...2012-01-01
6 Couldwell, William T.Surgical fidelity: comparing the microscope and the endoscopeBackground: Both the microscope and the endoscope are widely used as visualization tools in neurosurgery; however, surgical dexterity when operating with endoscopic visual control may differ. The aim of this study was to compare the surgical fidelity when using each of these visualization tools. Met...2013-01-01
7 Couldwell, William T.Resident curriculum guidelines for neurosurgeryThis curriculum was created to detail the body of knowledge that should be attained by an individual completing residency training in neurological surgery. The specific structure of resident education in neurological surgery is defined by the American Board of Neurological Surgery, and each program...Residency training; Neurological surgery2000
8 Kestle, John R. W.; Brockmeyer, Douglas LeeCranial base strategies for resection of craniopharyngioma in childrenThe optimal treatment of craniopharyngioma in children remains a challenge. The use of complete excision to minimize recurrence continues to be controversial because of the risk of postoperative morbidity and death. Advances in skull base approaches, modern microsurgical techniques, neuroimaging, an...Craniopharyngioma; Surgical approach; Skull base surgery2005
9 Couldwell, William T.Management of pituitary adenomasWe present an overview of the management of pituitary adenomas, with discussions of microanatomy, of diagnostic studies of general neuroendocrine function, and of radiologic evaluation. We discuss the diagnosis of pituitary adenoma and its treatment with sections on null cell, prolactin (PRL)-secre...Pituitary adenoma; Transsphenoidal surgery; Corticotropin; Prolactin; Growth hormone; Transcranial surgery1994
10 Couldwell, William T.Irving S. Cooper (1922-1985): a pioneer in functional neurosurgeryIrving S. Cooper (1922-1985), the son of a salesman, worked his way through high school, college, and medical school to become one of the pioneers in functional neurosurgery. He developed several novel techniques for the surgical management of Parkinson's disease and other crippling movement disord...Functional neurosurgery; Cryosurgery; Dystonia; Movement disorder; Parkinson's disease; Thalamotomy; Tremor; Neurosurgical history1998
11 Couldwell, William T.Utilization of unilateral and bilateral stereotactically placed adrenomedullary-striatal autografts in Parkinsonian humans: rationale, techniques, and observationsA limited clinical pilot study involving an amalgam of specialized disciplines including neurology, neuropharmacology, neuropsychology, neurosurgery, neuroanesthesia, neuroradiology, surgical pathology, neuropathology, and urological surgery was organized to clarify issues related to patient selecti...Adrenal medullary graft; Autograft; Brain graft; Neural transplantation; Parkinsonism; Stereotaxy1990
12 Couldwell, William T.; Nelson, Don HarryNelson syndrome: historical perspectives and current conceptsThe appearance of an adrenocorticotropic hormone (ACTH)-producing tumor after bilateral adrenalectomy for Cushing disease was first described by Nelson in 1958. The syndrome that now bears his name was characterized by hyperpigmentation, a sellar mass, and increased plasma ACTH levels. The treatment...2007-01-01
13 Couldwell, William T.; Harnsberger, H. RicOronasopharyngeal chordomasBackground: Chordomas are rare tumors derived from notochordal remnants. The authors report on a series of three cases of primary familial oronasopharyngeal chordomas treated at our institution. Methods: A retrospective chart review was completed of the three cases of primary familial oronasopharyng...Oronasopharyngeal; Chordoma; Pharynx; Notochord; Transoral; Skull base2009
14 Couldwell, William T.Man for all seasons: W.W. KeenWILLIAM WILLIAMS KEEN was the catalyst for the advent of neurosurgery in the United States. He served in the Civil War and collaborated with Silas Weir Mitchell in studying injuries sustained to the nervous system. These studies culminated in the publication in 1864 of Gunshot Wounds and Other Inj...Brain tumor2002
15 Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L.Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction.Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r...Central Neurogenic H yperventilation; Ocular Motor Dysfunction1990-11
16 Dailey, Andrew T.Pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in childrenMutism following posterior fossa tumor resection in pediatric patients has been previously recognized, although its pathophysiology remains unclear. A review of the available literature reveals 33 individuals with this condition, with only a few adults documented in the population. All of these pati...Vermis; Posterior fossa tumor; Pediatric patients1995
17 Kestle, John R. W.Effect of hyperventilation on regional cerebral blood flow in head-injured childrenObjectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre...Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children1997
18 Dailey, Andrew T.Surgical treatment of occipitocervical instabilityOBJECTIVE: Instability of the occipitocervical junction can be a challenging surgical problem because of the unique anatomic and biomechanical characteristics of this region. We review the causes of instability and the development of surgical techniques to stabilize the occipitocervical junction. ...Occipitocervical instability2008
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